Goldfrank's Toxicologic Emergencies 9th Edition

The most trusted, rigorous, and up-to-date toxicology resource and educational companion available – now in full color 

Goldfrank’s Toxicologic Emergencies continues to be the source you can turn to first for any poisoning or overdose. The text provides clear information on every aspect of toxicologic emergencies, from pharmacology to clinical presentation to management. 

Fully referenced and featuring a consistent organization, Goldfrank’s begins with an in-depth examination of general principles of medical toxicology. It then progresses to the biochemical principles and molecular basis of toxicology, and provides detailed insight into how xenobiotics affect vital signs, organs, and systems throughout the body. Next, a wide spectrum of clinically important exposures -- including drugs, plants, metals, household products, occupational and environmental xenobiotics are covered within logical categories for easy access to information. Finally, the book concludes with sections on principles of practicing clinical toxicology in today’s challenging healthcare environment.

New to this edition

• Full-color design and uniformly drawn figures clarify key concepts.
• Special Considerations focus on decision-making in unique toxicologic circumstances, that influence clinical practice and have the potential to improve patient care.
• Antidotes in Depth, following pertinent chapters, place each antidote in its proper context to ensure immediate availability of essential information relevant for clinical use.
• More clinically-relevant figures and quick-reference tables.
• Online learning center, available at www.goldfrankstoxicology.com, includes case studies, and a database of multiple choice questions that allow you to create a custom test for review and study.
• Every chapter is thoroughly rewritten and new chapters are added to reflect the very latest thinking in the field.

Contents

• 1. Historical Principles and Perspectives
• 2. Toxicologic Plagues and Disasters in History

PART A: The general approach to medical toxicology

• 3. Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes
• 4. Principles of Managing the Acutely Poisoned or Overdosed Patient
• 5. Diagnostic Imaging
• 6. Laboratory Principles
• 7. Techniques Used to Prevent Gastrointestinal Absorption
• 8. Pharmacokinetic and Toxicokinetic Principles
• 9. Principles and Techniques Applied to Enhance Elimination
• 10. Use of The Intensive Care Unit

PART B: The fundamental principles of medical toxicology

Section 1: Biochemical and Molecular Basis

• 11. Chemical Principles
• 12. Biochemical and Metabolic Principles
• 13. Neurotraansmitters and Neuromodulators
• 14. Withdrawal Principles

Section 2: Pathophysiologic Basis: Organ Systems

• 15. Thermoregulatory Principles
• 16. Fluid, Electrolyte, and Acid-Based Principles
• 17. Psychiatric Principles
• 18. Neurologic Principles
• 19. Ophthalmic Principles
• 20. Otolaryngologic Principles
• 21. Respiratory Principles
• 22. Electrophysiologic and Electrocardiographic Principles
• 23. Hemodynamic Principles
• 24. Hematologic Principles
• 25. Gastrointestinal Principles
• 26. Hepatic Principles
• 27. Renal Principles
• 28. Genitourinary Principles
• 29. Dermatologic Principles

Section 3: Special Populations

• 30. Reproductive and Perinatal Principles
• 31. Pediatric Principles
• 32. Geriatric Principles
• 33. Postmortem Toxicology

PART C: The clinical basis of medical toxicology

Section 1: Case Studies

A. Analgesics and Antiinflammatory Medications

• 34. Acetaminophen
• 35. Salicylates
• 36. Nonsteroidal Antiinflammatory Drugs
• 37. Colchicine, Podophyllin, and the Vinca Alkoloids
• 38. Opioids

B. Foods, Dietary and Nutritional Agents

• 39. Dieting Agents and Regimens
• 40. Iron
• 41. Vitamins
• 42. Essential Oils
• 43. Herbal Preparations
• 44. Athletic Performance Enhancers
• 45. Food Poisoning
• 46. Botulism

C. Pharmaceuticals

• 47. Anticonvulsants
• A9. L-Carnitine
• 48. Antidiabetics and Hypoglycemics
• 49. Thyroid and Antithyroid Medications
• 50. Antihistamines and Decongestants
• 51. Antimigraine Medications
• 52. Antineoplastics Overview
• 53. Antineoplastics: Methotrexate
• 54. Miscellaneous Antineoplastics
• 55. Pharmaceutical Additives

D. Antimicrobials

• 56. Antibacterials, Antifungals, and Antivirals
• 57. Antituberculous Medications
• 58. Antimalarials

E. Cardiopulmonary Medications

• 59. Anticoagulants
• 60. Calcium Channel Blockers
• 61. B-Adrenergic Antagonists
• 62. Other Antihypertensives
• 63. Antidysrhythmics
• 64. Cardioactive Steroids
• 65. Methylxanthines and Selective B2 Adrenergic Agonists

F. Anesthetics and Related Medications

• 66. Local Anesthetics
• 67. Inhalational Anesthetics
• 68. Neuromuscular Blockers

G. Psychotropic Medications

• 69. Antipsychotics
• 70. Lithium
• 71. Monoamine Oxidase Inhibitors
• 72. Serotonin Reuptake Inhibitors and Atypical Antidepressants
• 73. Cyclic Antidepressants
• 74. Sedative-Hynotics

H. Substances of Abuse

• 75. Amphetamines
• 76. Cocaine
• 77. Ethanol
• 78. Ethanol Withdrawal
• 79. Disulfiram and Disulfiram-Like Reactions
• 80. Y-Hydroxybutyric Acid
• 81. Inhalants
• 82. Hallucinogens
• 83. Cannabinoids
• 84. Nicotine
• 85. Phencyclidine and Ketamine
• 86. Aluminum

I. Metals

• 87. Antimony
• 88. Arsenic
• 89. Bismuth
• 90. Cadmium
• 91. Chromium
• 92. Cobalt
• 93. Copper
• 94. Lead
• 95. Manganese
• 96. Mercury
• 97. Nickel
• 98. Selenium
• 99. Silver
• 100. Thallium
• 101. Zinc

J. Household Products

• 102. Antiseptics, Disinfectants, and Sterilants
• 103. Camphor and Moth Repellents
• 104. Caustics
• 105. Hydrofluoric Acid and Fluorides
• 106. Hydrocarbons
• 107. Toxic Alcohols

K. Pesticides

• 108. Pesticides: An Overview with a Focus on Principles and Rodenticides
• 109. Barium
• 110. Sodium Monofluoroacetate and Fluroacetamide
• 111. Phosphorus
• 112. Strychnine
• 113. Insecticides: Organic Phosphorus Compounds and Carbamates
• 114. Insecticides: Organic Chlorines, Pyrethrins/Pyrethroids, and Insect Repellents,
• 115. Herbicides
• 116. Methyl Bromide and Other Fumigants

L. Natural Toxins and Envenomations

• 117. Mushrooms
• 118. Plants
• 119. Arthropods
• 120. Marine Envenomations
• 121. Snakes and Other Reptiles

M. Occupational and Environmental Toxins

• 122. Industrial Poisoning: Information and Control
• 123. Nanotoxicology
• 124. Simple Asphyxiants and Pulmonary Irritants
• 125. Carbon Monoxide
• 126. Cyanide Andhydrogen Sulfide
• 127. Methemoglobin Inducers
• 128. Smoke Inhalation

N. Disaster Preparedness

• 129. Risk Assessment and Risk Communications
• 130. Hazmat Incident Response
• 131. Chemical Weapons
• 132. Biological Weapons
• 133. Radiation

Section 2: Poison Centers and Epidemiology

• 134. Poison Prevention and Education
• 135. Poison Centers and Poison Epidemiology
• 136. International Perspectives on Toxicology
• 137. Principles of Epidemiology and Research Design
• 138. Adverse Drug Events and Postmarketing Surveillance
• 139. Medication Safety and Adverse Drug Events
• 140. Risk Management and Legal Principles

Index

About the Authors

• Lewis S. Nelson, MD, FAACT, FACEP, FACMT, Associate Professor of Emergency Medicine, New York University School of Medicine; Attending Physician, Emergency Medicine, Bellevue Hospital Center and New York University, Langone Medical Center; Director, Fellowship in Medical Toxicology, New York City Poison Center and New York University, School of Medicine, New York, NY.
• Neal A. Lewin, MD, FACEP, FACMT, FACP, The Stanley and Fiona Druckenmiller Clinical Professor of Emergency Medicine and Medicine (Pharmacology), New York University School of Medicine; Director, Didactic Education, Emergency Medicine Residency; Attending Physician, Emergency Medicine and Internal Medicine, Bellevue Hospital Center and New York University Langone Medical Center; Consultant, New York City Poison Center, New York, NY.
• Mary Ann Howland, PHARMD , DABAT, FAACT, Clinical Professor of Pharmacy, St. John’s University, College of Pharmacy; Adjunct Professor of Emergency Medicine, New York University School of Medicine, Bellevue Hospital Center and New York University Langone Medical Center; Senior Consultant in Residence, New York City Poison Center, New York, NY.
• Robert S. Hoffman, MD, FAACT, FACMT, Associate Professor, Emergency Medicine and Medicine (Pharmacology), New York University School of Medicine; Attending Physician, Emergency Medicine and Internal Medicine, Bellevue Hospital Center and New York University Langone Medical Center; Director, New York City Poison Center, New York, NY.
• Lewis R. Goldfrank, MD, FAAEM, FAACT, FACEP, FACMT, FACP, Herbert W. Adams Professor and Chair, Department of Emergency Medicine, New York University School of Medicine; Director, Emergency Medicine, Bellevue Hospital Center and New York University Langone Medical Center; Medical Director, New York City Poison Center, New York, NY.
• Neal E. Flomenbaum, MD, FACEP, FACP, Professor of Clinical Medicine, Weill Cornell Medical College of Cornell University; Emergency Physician-in-Chief, New York-Presbyterian Hospital, Weill Cornell Medical Center; Consultant, New York City Poison Center, New York, NY.

Product Details

• Hardcover: 1968 pages
• Publisher: McGraw-Hill Professional; 9 edition (July 16, 2010)
• Language: English
• ISBN-10: 0071605932
• ISBN-13: 978-0071605939
• Product Dimensions: 11.1 x 8.8 x 2.5 inches

List Price: $259.00