Casarett and Doull's Essentials of Toxicology 2nd Edition (Lange)

Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the field’s gold-standard text Casarett & Doull’s Toxicology: The Basic Science of Poisons. Presented in full color for the first time, the book combines an accessible and engaging approach with coverage of essential introductory concepts to provide you with a solid grounding in basic and medical toxicology. Succinct, yet comprehensive, the text covers essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents – from pesticides to radiation.

Key Features

• A complete basic overview of poisons and their clinical management.
• Reflects the expertise of more than fifty renowned contributors.
• A summary of important points is included at the beginning of each chapter and multiple-choice review questions appear at the conclusion.
• Important chapters on forefront topics such as Analytic/Forensic Toxicology, Clinical Toxicology, Occupational Toxicology, Air Pollution, and Ecotoxicology.

Table of contents

Unit 1: General Principles Of Toxicology

• Chapter 1. History and Scope of Toxicology
• Chapter 2. Principles of Toxicology
• Chapter 3. Mechanisms of Toxicity
• Chapter 4. Risk Assessment

Unit 2: Disposition Of Toxicants

• Chapter 5. Absorption, Distribution, and Excretion of Toxicants
• Chapter 6. Biotransformation of Xenobiotics
• Chapter 7. Toxicokinetics

UNIT 3: Nonorgan-Directed Toxicity

• Chapter 8. Chemical Carcinogenesis
• Chapter 9. Genetic Toxicology
• Chapter 10. Developmental Toxicology

Unit 4: Target Organ Toxicity

• Chapter 11. Toxic Responses of the Blood
• Chapter 12. Toxic Responses of the Immune System
• Chapter 13. Toxic Responses of the Liver
• Chapter 14. Toxic Responses of the Kidney
• Chapter 15. Toxic Responses of the Respiratory System
• Chapter 16. Toxic Responses of the Nervous System
• Chapter 17. Toxic Responses of the Ocular and Visual System
• Chapter 18. Toxic Responses of the Heart and Vascular System
• Chapter 19. Toxic Responses of the Skin
• Chapter 20. Toxic Responses of the Reproductive System
• Chapter 21. Toxic Responses of the Endocrine System 

Unit 5: Toxic Agents

• Chapter 22. Toxic Effects of Pesticides
• Chapter 23. Toxic Effects of Metals
• Chapter 24. Toxic Effects of Solvents and Vapors
• Chapter 25. Toxic Effects of Radiation and Radioactive Materials
• Chapter 26. Toxic Effects of Terrestrial Animal Venoms and Poisons
• Chapter 27. Toxic Effects of Plants, Fungi, and Algae

Unit 6: Environmental Toxicology

• Chapter 28. Air Pollution
• Chapter 29. Ecotoxicology

Unit 7: Applications Of Toxicology

• Chapter 30. Food Toxicology
• Chapter 31. Analytic/Forensic Toxicology
• Chapter 32. Clinical Toxicology
• Chapter 33. Occupational Toxicology

Self-Assessment Questions and Answers
Index

About the Authors

• Curtis D. Klaassen, PhD, University Distinguished Professor and Chair, Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS.
• John B. Watkins, III, PhD, Assistant Dean and Director, Professor of Pharmacology and Toxicology, Medical Sciences Program, Indiana University School of Medicine, Bloomington, IN.

Product Details

• Paperback: 472 pages
• Publisher: McGraw-Hill Professional; 2 edition (July 12, 2010)
• Language: English
• ISBN-10: 0071622403
• ISBN-13: 978-0071622400
• Product Dimensions: 10.9 x 8.5 x 0.9 inches

List Price: $69.95