Thirteen years ago, the journal of the American Medical Association (JAMA 1996) reported that 108, 000 Americans died in hospital from adverse drug reactions and 2.2 million Americans had reactions to FDA approved medications. In the UK an estimated 1.6 million bed days are due to in-patient adverse drug reactions and up to 6.5% of new patient admissions may be related to an adverse drug reaction. Recent estimates suggest that adverse drug reactions cost the NHS in England in excess of £637 million annually.
In 2009, in the UK, drugs are increasingly available over the counter and online without prescription. Furthermore, there is widespread use of numerous herbal medicines from relatively under-regulated suppliers and the constituents of such products are often not known. This clinical reality of the widespread use of potent medicines – be they allopathic or traditional – showed us the need for a practical hands-on guide that aims to be a compact, succinct and accessible source of information for practitioners, prescribers and the public about adverse drug interactions.
We are aware that there are numerous sources of information available to prescribers, pharmacists and users about adverse drug interactions and that new drug interactions are reported on a regular basis. This makes it difficult for the busy
practicing health-care professional to keep up with the related literature. We have aimed to produce a user-friendly resource that not only describes the potential interactions themselves, but also gives practical advice about what clinical features to look out for, what to do to try to minimize their occurrence, and what to do if they occur. We aim to produce a source of information that can be used within the time frame of a consultation, to provide some guidance to prescribers, dispensers and users to minimize the risk of a drug interaction occurring.
Thus, this book intends to provide a source of easily accessible and concise information and guidance to busy prescribers, dispensers and users to minimize this avoidable or preventable hazard.
- The Authors -
Contents
- About the authors
- Preface
- Acknowledgements
- Abbreviations
- Index of drug names
- Introduction
- Clinical features of some adverse drug interactions
- Part 1 Cardiovascular drugs
- Part 2 Drugs acting on the nervous system
- Part 3 Anticancer and immunomodulating drugs
- Part 4 Anticoagulants
- Part 5 Antidiabetic drugs
- Part 6 Other endocrine drugs
- Part 7 Analgesics
- Part 8 Musculoskeletal drugs
- Part 9 Anaesthetic drugs
- Part 10 Drugs to treat infections
- Part 11 Drugs acting on the gastrointestinal tract
- Part 12 Respiratory drugs
- Part 13 Metabolic drugs
- Part 14 Drugs used in obstetrics and gynaecology
- Part 15 Urological drugs
- Part 16 Drugs of abuse
- Part 17 Miscellaneous
- Part 18 Over-the-counter drugs
ABOUT THE AUTHORS
- Lakshman Karalliedde is currently Visiting Senior Lecturer at the Division of Public Health Sciences, King’s College London School of Medicine, King’s College, London, UK; and Senior Collaborator at the South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Sri Lanka. He is also Consultant Medical Toxicologist, Chemical Hazards & Poisons Division (London), Health Protection Agency, UK. Dr Karalliedde was formerly Senior Lecturer and Honorary Consultant Anaesthetist at the United Medical & Dental Schools of Guy’s & St Thomas’ Hospitals, London, UK; and Medical Toxicologist at Guy’s Poisons Unit and National Poisons Information Service, Guy’s & St Thomas’ NHS Foundation Trust, London, UK.
- Simon F. J. Clarke is Consultant Emergency Medicine Physician, Frimley Park NHS Foundation Trust, UK; and Honorary Consultant Medical Toxicologist, Chemical Hazards and Poisons Division (London), Health Protection Agency, UK.
- Ursula Collignon is Senior Pharmacist at Guy’s & St Thomas’ NHS Foundation Trust, London, UK.
- Janaka Karalliedde is Clinical Lecturer in Diabetes and Endocrinology in the Cardiovascular Division, King’s College London School of Medicine, King’s College London, UK.
Product Details
- Paperback: 352 pages
- Publisher: Oxford University Press, USA; 1 edition (April 12, 2010)
- Language: English
- ISBN-10: 0340927690
- ISBN-13: 978-0340927694
- Product Dimensions: 7.8 x 5.1 x 1.3 inches
List Price: $45.00