Edmonds: A Practical Manual of Diabetic Foot Care 2nd Edition

The first edition of 'A Practical Manual of Diabetic Foot Care' was named ‘Medical Book of the Year 2004’ by the British Medical Association, and we were pleased on behalf of all workers in this difficult field that the importance of the diabetic foot has been thus recognized and acknowledged as a major area of interest.

A new edition is an opportunity to present revised and updated material, together with many new photographs and case studies and descriptions of fresh developments in the field.

In this second edition, the author still emphasize the importance of the simple staging system, as a fundamental part of the approach to the management of the diabetic foot. By applying the staging process to all diabetic foot patients it is possible, through one simple assessment, to detect the conditions that need addressing and plan their treatment using simple but fundamental principles.

The simple staging system has therefore been developed as a practical, treatment-based tool that provides a framework for diagnosing and managing the diabetic foot, and this chapter describes the application of this system through:

• Practical assessment, which consists of history-taking, examination and investigations.
• Classification of the diabetic foot into the neuropathic and neuroischaemic foot.
• Staging the foot. The six specific stages in the natural history of the diabetic foot.
• Management plan for each stage.

The clinical assessment we describe is quick and simple, but will enable the practitioner to make a basic classification and staging and the foot can then be placed into the correct stage, which has specific implications for treatment. Investigations will be needed to assess severity so as to determine treatment.

Following this system will enable the practitioner to make rapid, effective decisions that will detect problems early, organize rapid treatment and prevent deterioration and progression.

All diabetic foot enthusiasts will enjoy this new edition of this Practical Manual, and will find it as useful, practical and easy to use as its predecessor.

Contents 

Acknowledgements

Prologue

1 Introduction

• Practical Assessment
• Classification and Staging
• Multidisciplinary Management
• Practice Points
• Further Reading

2 Stage 1: The Normal Foot

3 Stage 2: The High-risk Foot

4 Stage 3: The Ulcerated Foot

5 Stage 4: The Infected Foot

6 Stage 5: The Necrotic Foot

7 Stage 6: The Unsalvageable Foot

8 Surgical Approach to the Diabetic Foot

Index

About the Author

• Dr Michael E. Edmonds MD, FRCP, Consultant in Diabetes, King's College Hospital, London, is a world-renowned expert on foot problems in diabetes. He has lectured on the topic throughout the world and gave the inaugural Roger Pecoraro Lecture at the American Diabetes Association's annual meeting. He is also Chairman of the Diabetic Foot Study Group of the European Association of the Study of Diabetes.
• Mrs Alethea V. M. Foster BS (Hons) PGCE, MChS, SRCh, DipPodM recently retired as the Chief Podiatrist, King's College Hospital, London, wher she was involved in the development of the UK Government's National Serviec Framework for Diabetes implemented in all hospitals, clinics and primary care practices form 2004. In May 2003, Alethea was the first podiatrist to be awarded the International Diabetic Foot Award, which is only awarded every four years to an indvidual who has played a pivotal role in developing diabetic foot care.
• Dr Lee Sanders DPM, Chief of Podiatry, Acute Cre/Specialty Services, Department of Veterans Affairs Medical Center, Lebanon, PA, USA. He is past President for Health Care and Education of the American Diabetes Association, the first podiatrist in ADA's history to be elected to this prestigious position. Dr Sanders is also a medical historian, with a special interest in the history of diabetes.

Product Details

• Hardcover: 304 pages
• Publisher: Wiley-Blackwell; 2 edition (February 19, 2008)
• Language: English
• ISBN-10: 1405161477
• ISBN-13: 978-1405161473
• Product Dimensions: 7.7 x 0.8 x 10 inches

List Price: $171.95 

 

Scobie: Atlas of Diabetes Mellitus 3rd Edition (Encyclopedia of Visual Medicine Series)

The world is witnessing an increase in new cases of diabetes, in both the developed and the developing nations, of near epidemic proportion. This ubiquitous condition will have an ever-increasing impact on all aspects of medicine and public health. It follows that all practicing physicians must seek to gain at least a basic knowledge and understanding of this important global health problem that is so closely linked to the increasing prevalence of obesity.

Diabetes is the paradigm of a condition that necessitates a multidisciplinary approach to its management and treatment. Primary care physicians, hospital physicians, surgeons, nurses, dieticians, psychologists, podiatrists and ophthalmologists are all drawn into this process. In addition, medical students and postgraduate doctors need to learn about diabetes and its protean manifestations.

The third edition of this book continues to build on the previous two editions in providing a clinical and scientific background to the diagnosis, clinical presentations and treatment of diabetes mellitus with a further aim of portraying the wide and varied expressions of diabetes and its complications as an aid to their more ready recognition in clinical practice. It also aims to illustrate the breathtaking developments that are taking place in the field of new therapies for diabetes.

This Atlas should, therefore, be of interest to all those who are involved in the provision of diabetic health care and should provide some insight into the fruits of the explosion of basic science and clinical research that has been conducted in an attempt to further our understanding of diabetes and to care better for our diabetic patients.

Contents
1. Introduction

• Definition of Diabetes
• Diagnosis of Diabetes
• Classification of Diabetes
• Epidemiology of Diabetes
• Bibliography

2. Pathogenesis

• Type 1 Diabetes Mellitus
• Type 2 Diabetes Mellitus
• Other Types of Diabetes
• the Obesity Epidemic
• Prevention of Diabetes
• Bibliography

3. Treatment

• Dietary Treatment for Type 1 Diabetes Mellitus
• Dietary Treatment for Type 2 Diabetes Mellitus
• Insulin Treatment of Type 1 Diabetes Mellitus
• Blood Glucose Monitoring
• Role of Education
• Assessment of Glycemic Control
• Drug and Insulin Treatment for Type 2 Diabetes Mellitus
• Islet Cell and Pancreatic Transplantation
• Bibliography

4. Treatment of children and adolescents with diabetes

5. Diabetes and surgery

• Type 2 Diabetes Not on Insulin Therapy
• Patients on Insulin Therapy

6. Acute complications of diabetes

• Hypoglycemia
• Diabetic Ketoacidosis and Hyperosmolar Non-ketoacidotic Coma
• Bibliography

7. Chronic complications of diabetes

• Diabetic Retinopathy
• Diabetic Nephropathy
• Diabetic Neuropathy
• Major Vascular Disease
• Hypertension
• the Diabetic Foot
• Erectile Dysfunction in Diabetes
• Non-alcoholic Steatohepatosis
• the Skin in Diabetes
• Rarer Manifestations of Diabetes Mellitus
• Bibliography

8. Diabetic dyslipidemia
9. Diabetes and pregnancy
10. Living with diabetes
11. Future developments in diabetes
Index

 

Book Review

The third edition of Ian Scobie’s Atlas of Diabetes Mellitus, building on the success of the two previous editions, goes a long way towards making this task easier and remains a testimonial to the fact that a picture is indeed worth at least a thousand words. This Atlas begins with a brief overview of the diagnosis, pathogenesis and treatment of diabetes with special reference to the complications of diabetes and the treatment of children and adolescents. Specific chapters cover diabetic dyslipidemia, diabetes and pregnancy and what it is like to live with this chronic condition. These, and other sections, set the stage for the multitude of highly informative illustrations which follow. Most specialists in diabetes have seen real-life examples of the disease processes presented in this book but some may be very unfamiliar to the generalist.
Many excellent and comprehensive textbooks of diabetes are available, but I am unaware of any other illustrated text with the scope and breadth of Dr Scobie’s Atlas of Diabetes Mellitus. I have no doubt that both my students and I will continue to find this book useful for many years to come. I suspect that those of you who choose to add this excellent Atlas to your library will find that you will also share my enthusiasm for this delightful book.

- Robert A. Rizza MD, Rochester, MN - 

Product Details

 

• Hardcover: 136 pages
• Publisher: Informa Healthcare; 3 edition (October 27, 2007)
• Language: English
• ISBN-10: 0415376491
• ISBN-13: 978-0415376495
• Product Dimensions: 11.7 x 8.4 x 0.7 inches

List Price: $149.95 

 

Ahima: Metabolic Basis of Obesity

Overweight, defined as body-mass index (BMI) greater than 25, and obesity, defined as BMI greater than 30, are characterized by excessive fat accumulation which poses adverse risks to health. Worldwide, there are more than one billion overweight and 300 million obese adults. Obesity is a major risk factor for diabetes, cardiovascular disease, sleep apnea, non-alcoholic fatty liver disease, arthritis, cancer and other diseases, and has been associated with enormous health costs, premature death, reduction in the quality of life and disability. The increasing global incidence of child obesity is also a major concern. The obesity epidemic is not just a problem for industrialized societies. Indeed, obesity rates have risen three times or more over the past two decades in some developing countries. Although the growing obesity epidemic undoubtedly reflects profound changes in diet and lifestyle over recent decades, genetic factors are important in determining a person’s susceptibility to weight gain and adverse health consequences of obesity.

The goal of this book is to highlight the pathophysiolgy of obesity and associated diseases. While a completely comprehensive discussion of the metabolic basis of obesity is beyond the scope of this book, it presents in-depth reviews of a wide range of topics, including energy homeostasis and intermediary metabolism, adipocyte biology, central neuronal pathways, adipokines, cytokines, classical hormones, abnormal glucose and lipid metabolism, and dysregulation of major organs, with an emphasis on human obesity. These topics will be interesting and provide critical information on the metabolic basis of obesity to researchers, clinicians, students, and the public at large.

Contents

1 Principles of Human Energy Metabolism

• Energy Expenditure
• Measurement of Energy Expenditure
• Energy Balance and Implications for Obesity
• Metabolic Risk Factors for Weight Gain

2 Intermediary Metabolism of Carbohydrate, Protein, and Fat

• Carbohydrate and Energy Metabolism
• Triglyceride and Fatty Acid Metabolism
• Protein and Amino Acid Metabolism
• AMP-Activated Protein Kinase: An Integrated Modulator of Cellular Metabolism
• Transgenic Models: Some Answers and More Questions

3 Adipose Tissue Development, Structure and Function

• Multiple Functions of Adipose Tissue
• Biochemical Properties of Adipocytes
• Adipose Tissue is Connected to Other Physiological Systems
• Anatomical Distribution and Structure of Adipose Tissue
• In Vivo Regulation of WAT Expansion
• Regulation of White Adipocyte Differentiation
• Identification of White Adipocyte Progenitors
• Brown Adipose Tissue (BAT)
• In Vivo Regulation of BAT
• Recent Advances in Human Adult BAT

4 Adipokines in Health and Disease

• Leptin
• Adiponectin
• Resistin
• Other Adipokines Related to Obesity: Proinflammatory Cytokines, Retinol Binding Protein-4

5 Neural Control of Feeding and Energy Homeostasis

• Hypothalamic Regulation of Feeding and Energy Homeostasis
• Brainstem Regulation of Feeding and Energy Homeostasis
• Short-Term Regulation of Energy Homeostasis by Nutrients and Gut Hormones
• Long-Term Regulation of Energy Stores by Adiposity Hormones
• Role of Biogenic Amines in Feeding Regulation and Energy Homeostasis

6 Gastrointestinal Hormones and Obesity

• Hormones Secreted by the Upper Gastrointestinal Tract: Ghrelin, Cholecystokinin (CCK), Incretins and Enteroinsular Axis
• Hormones Secreted by the Distal Gut: Oxyntomodulin (OXM), Peptide YY (PYY)
• Pancreatic Hormones: Pancreatic Polypeptide (PP), Amylin (Islet Amyloid Polypeptide)
• Other Gut Hormones
• Bombesin-Related Peptides
• Hormonal Interactions

7 Genes and Human Obesity

• Heritability
• Gene–Environment Interaction
• Candidate Genes
• Common Obesity and Rare Gene Variation
• Linkage Studies
• Whole-Genome Association Studies
• Disparate Approaches Appear to Converge
• Unanticipated Genes
• Epigenetic Modification
• Applications: Prevention and Therapy

8 Classical Hormones Linked to Obesity

• Insulin and Obesity
• Glucocorticoids
• Thyroid Hormone
• Growth Hormone

9 Inflammation and Adipose Dysfunction

• Systemic Activation of Inflammatory Pathways
• Adipose-Specific Activation of Immune Pathways
• Adipose Leukocyte Infiltration
• Adipose Inflammation Attenuates Insulin Signaling
• Endotoxemia and Adipose TLR Signaling
• The Adipose Inflammatory Secretome
• Role of Intracellular Kinases
• Suppressor of Cytokine Signaling Proteins
• Modulation of Transcription Factors
• Gene Expression Profiling and Proteomics
• Therapeutic Implications
• Modulation of Systemic inflammation
• Modulation of Leukocyte Infiltration in Adipose

10 Insulin Resistance in the Metabolic Syndrome

• Clinical Versus molecular definitions of insulin resistance
• Insulin Signaling Pathway
• Metabolic Effects of Insulin Resistance: Lessons from Knockout Mice
• Molecular Mechanisms of Insulin Resistance
• Insulin Resistance in Humans

11 Pancreatic Islet b-Cell Failure in Obesity

• Neuropeptides Regulating the Islet–Hypothalamic Axis
• Gut Peptides Regulating the Islet–Hypothalamic Axis
• Adipokines and Cytokines Regulating the Islet–Hypothalamic Axis
• Potential Therapeutic Approaches to Pancreatic b-Cell Failure in Obesity

12 Non-Alcoholic Fatty Liver Disease and the Metabolic Syndrome

• NAFLD and the Metabolic Syndrome
• The Intertwined Paths of Insulin and Lipid Metabolism in the Pathogenesis of Hepatic Steatosis
• Pathogenesis of NASH

13 Sleep, Circadian Rhythms and Metabolism

• Molecular Relationships Between Metabolism and Circadian Rhythms
• From Circadian Disruption to Cardiometabolic Diseases
• Neurophysiological Structures: Interconnection Between Circadian, Sleep and Energy Centers
• From Metabolism to Circadian Cycles

14 Obesity and Cardiac Dysfunction

• Epidemiology and Pathophysiology of Cardiac Dysfunction in Human Obesity
• Comorbidities that Contribute to Cardiac Dysfunction in Obesity
• Mechanistic Insights Gained from Studies in Animal Models of Obesity
• Postulated Mechanisms for Cardiac Dysfunction in Obesity
• Clinical Considerations

15 Atherogenic Lipid Metabolism in Obesity

• VLDL Overproduction
• Reduced Hepatic Sensitivity to Insulin Leading to Increased Hepatic Lipogenesis, VLDL-Apolipoprotein-B Assembly and Secretion
• Impaired Catabolism of Atherogenic Lipoprotein Remnants
• Hypercatabolism of HDL

16 Gut Microbes, Immunity, and Metabolism

• Gut Microecology
• Current Technology and Characterization of the Gut Microbiota / Microbiome
• Metagonomics and Metabolomics
• The Gut Microbiota and Obesity
• Gut Microbiota and Diet
• Connecting the Gut Microbiome, Innate Immunity and Obesity
• Gut Microbiota and Type 1 diabetes
• Gut Microbiota and Nitrogen Balance

17 Impact of Obesity on Female Reproductive Health

• Energy Homeostasis and Reproduction
• Pathogenesis of Polycystic Ovary Syndrome

18 Lessons from HIV Lipodystrophy and Drug-Induced Metabolic Dysfunction

• Metabolic and Anthropometric Changes Among HIV-Infected Patients
• Effects of Specific Antiretroviral Medications on Body Composition and Metabolic Changes
• Genetic Predictors of Metabolic Risk in Acquired HIV Lipodystrophy Syndrome
• Cardiovascular Risk Among HIV-Infected Patients and Potential Mechanisms
• Novel Pharmacological Strategies to Improve Metabolic Abnormalities and Fat Redistribution Among HIV-Infected Patients

19 Principles of Obesity Therapy

• Clinical Evaluation of Obesity
• Treatment of Obesity
• Exercise
• Pharmacotherapy
• Surgical Treatment of Obesity

Index

About the Editor

• Rexford S. Ahima, Division of Endocrinology, Diabetes and Metabolism, and the Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, School of Medicine, 415 Curie Boulevard, 712A Clinical Research Building, Philadelphia, PA 19104, USA. Email: ahima@mail.med.upenn.edu

Product Details

• Hardcover: 405 pages
• Publisher: Springer; 1st edition (2011)
• Language: English
• ISBN-10: 1441916067
• ISBN-13: 978-1441916068
• Product Dimensions: 9.2 x 6.1 x 1.1 inches

List Price: $219.00 

 

Ain: The Complete Thyroid Book 2nd Edition

Roughly 12 percent of the adult population suffers from some form of thyroid disease. The most common thyroid diseases are autoimmune thyroid diseases, which affect women much more frequently than they do men, especially when women are pregnant or after delivery. These comprise Hashimoto’s disease (see Chapter 5) and Graves’ disease (see Chapter 6). Subclinical hypothyroidism and hyperthyroidism are also becoming more of a concern, particularly with an aging population and in light of the fact that so many early signs of thyroid disease can be masked by or mimic a host of other disorders. More and more people are now being definitively diagnosed with an underlying thyroid disease instead of being misdiagnosed with other diseases.

Thyroid cancer, still considered a rare cancer, constituting only about 2 percent of all cancers, is now considered the fastest-rising cancer among women in the United States, rising in incidence faster than lung or breast cancers. And in both sexes, thyroid cancer diagnoses have increased precipitously. Part of the rise in incidence likely has to do with better screening and information about early signs of thyroid cancer. In the past, many patients with thyroid cancers were not diagnosed early enough, and some of these cancers were missed until they were very aggressive and hard to treat.

Thyroid disease in the developing world is still widespread because of iodine deficiency. This is something we discuss in both Chapters 1 and 3. Poor mental development, caused by hypothyroidism in infants and children, is partly to blame for the depressed economies of many third world nations, with more than 500 million people at risk.

All in all, thyroid disease constitutes one of the most significant categories of health problems, notable for its frequency, its dramatic effects on world society, its spectacular consequences on individuals’ well-being, and its remarkable response to appropriate treatment.

Combining the expertise of two pioneers in the field--world-renowned thyroid specialist Kenneth Ain, M.D., and bestselling thyroid author and bioethicist M. Sara Rosenthal, Ph.D.--The Complete Thyroid Book provides all the essential information on the diagnosis, options, and treatment of thyroid disease.

Covering both state-of-the-art and standard-of-care treatments for every thyroid condition imaginable, this comprehensive resource gives you vital information on:

• The basics--what the thyroid does and how it works.
• Thyroid tests, scans, medication, and treatments.
• Hypothyroidism, hyperthyroidism, and thyroid hormone.
• Autoimmune thyroid disease and thyroid eye disease.
• Thyroid nodules, goiter, and thyroid cancer.
• Thyroid disease in pregnancy and menopause and among seniors, infants, and children.
• Thyroid disease and obesity, heart disease, fatigue, and mental health.
• Nutrition and complementary therapies. 

Contents
Part 1 The Basics 1
1 What Is the Thyroid, and What Does It Do? 3

• How It Formed, Where It Is, What It Does 3
• An Introduction to Thyroid Hormone 9

2 Tests and Labs: Diagnosing Thyroid Disease 13

• Tests That Measure Thyroid Hormone Levels 14
• TSH: The Most Sensitive Test to Assess Thyroid Hormone Status 15
• Thyroglobulin: The Specifi c Thyroid Protein 18
• Thyroid Hormone-Binding Proteins 19
• Measuring Thyroid Antibodies 20
• Dynamic Tests of Thyroid Function 22
• Tests of Metabolism 22
• Radioactive Thyroid Tests 24
• X-Rays, Ultrasounds, and Other Diagnostic Pictures 31
• Pathology: Do You Need Surgery? What Did the Surgeon Find? 34

3 Hypothyroidism: The Most Common Problem 39

• Why Am I Hypothyroid? 39
• Slowing Down: Signs of Hypothyroidism 47
• Diagnosing Hypothyroidism 52
• Treating Hypothyroidism 53
• Why Do I Still Feel Hypothyroid? 61

4 Too Much Thyroid Hormone: Thyrotoxicosis 63

• Symptoms of Too Much Thyroid Hormone 63
• The Emotional Effects of Thyrotoxicosis 71
• Causes of Thyrotoxicosis Without Hyperthyroidism 75
• Thyrotoxicosis with Hyperthyroidism 77
• Intrinsic Thyroid Autonomy: Independent Thyroid Hormone Manufacturers 77
• Diagnosing Thyrotoxicosis and/or Hyperthyroidism 78
• Treating Thyrotoxicosis 79

5 Hashimoto’s Thyroiditis and Other Types of Thyroiditis 81

• What Is an Autoimmune Disorder? 81
• Hashimoto’s Thyroiditis 84
• Other Common Autoimmune Disorders 89
• Other Forms of Thyroiditis 93

6 Graves’ Disease 97

• What Happens in Graves’ Disease? 97
• Diagnosing Graves’ Disease 101
• Treating Graves’ Disease 101
• Screening Family Members for Graves’ Disease 107
• Are There Natural Therapies for Graves’ Disease? 107

7 Goiter: An Enlarged Thyroid Gland 109

• Evaluating a Goiter 109
• Types of Goiter 113

8 Thyroid Nodules 117

• Finding a Thyroid Nodule 117
• Steps in Evaluating a Thyroid Nodule 118
• Hot Nodules 122
• Radiation Exposure to the Neck During Childhood 125

9 Thyroid Cancer 129

• Who Gets Thyroid Cancer? 130
• What Causes Thyroid Cancer? 130
• Types of Thyroid Cancers and Their Behavior 132
• Treatment for Papillary and Follicular Thyroid Cancers 137
• Diagnostic Evaluation: Long-Term Follow-Up 143

10 Thyroid Hormone: The Inside Scoop 145

• How It All Started 145
• T4: The Details 146
• T3: Specifi c and Limited Uses 152
• Mixtures of T3 and T4 154
• Thyroid Extracts, or Natural Thyroid Hormone 155

11 Other Drugs Used in Thyroid Disease 157

• Drugs Used to Treat Hyperthyroidism 157
• Stable Iodide 162
• Potassium Perchlorate 163
• Lithium Carbonate 164
• Treatment of Hypoparathyroidism: Low Calcium 164

12 Radioactive Iodine Therapy 169

• What Is Radioactivity? 170
• Types of Treatment with Radioactive Iodine 172

Part 2 People in Special Circumstances 181
13 Thyroid Disease in Pregnancy and After Delivery 183

• The Normal Thyroid in Pregnancy 184
• Being Pregnant with Preexisting Thyroid Disease 187
• Gestational Thyroid Disease (Thyroid Disease During Pregnancy) 189
• Discovering Thyroid Nodules in Pregnancy 194
• After the Baby Is Born 194

14 Thyroid Disease During Menopause 197

• Natural Menopause 197
• HRT, Menopause, and Thyroid Disease 200
• Osteoporosis 203
• Staying Alert About Heart Disease 207

15 Thyroid Disease in Infants and Children 209

• Thyroid Disease in Newborns and Infants 210
• Thyroid Disease in Children and Adolescents 213

16 Thyroid Disease and Obesity 221

• Defining Obesity 222
• Inappropriate Drug Treatments for Obesity 228
• Lowering Fat and Healthy Eating 229

17 Thyroid Disease in Older Individuals 233

• Hypothyroidism in Older Persons 233
• Thyrotoxicosis in Older Persons 235
• Other Thyroid Problems 237
• Thyroid Disease in a Person with Alzheimer’s Disease 237

18 Thyroid Hormone Resistance and Rare Genetic Disorders of the Thyroid 241

• Resistance to Thyroid Hormone (RTH) or
• Thyroid Hormone Resistance 242
• Pituitary and Hypothalamic Diseases and Other
• Genetic Disorders 244

Part 3 Living Well After Treatment 249
19 Thyroid Misconceptions and Misinformation 251

• False Statements About Hypothyroidism 254
• Misconceptions About Radioactive Iodine (RAI) 263
• Other Myths About Thyroid Cancer 267

20 Special Diets for Thyroid Disease and Healthy Eating 271

• The High-Fiber Diet for Hypothyroidism 271
• The Low-Iodine Diet (LID) 275
• What to Eat if You’re Hyperthyroid 277
• What to Eat After Treatment for Thyroid Disease 277
• The Mediterranean Diet 279

21 Making an Informed Decision 281

• The Standards of Care 281
• What You Should Know About Ethical Guidelines
• in Health Care 285
• Steps Toward Informed Decision Making 289

Part 4 Complications of Thyroid Disease 291
22 Coping with Thyroid Eye Disease 293

• What Is Thyroid Eye Disease? 293
• Battling the Bulge: Treating TED 298
• Dry Eyes 300

23 Coping with Depression, Anxiety, and Other Mental Health Disorders 303

• Unipolar Depression and Hypothyroidism 304
• Anxiety, Panic Disorder, and Thyroid Disease 309
• When Your Body Feels Your Emotional Pain: Somatization Disorder 311

24 Coping with Heart Disease 315

• Heart Complications from Hypothyroidism 316
• Heart Complications from Thyrotoxicosis 321

25 Coping with Fatigue 325

• Normal Fatigue 325
• Abnormal Fatigue: Chronic Fatigue Syndrome 330

26 Thyroid and Public Health 335

• Environmental Issues in Thyroid and Endocrine Disease 335
• Screening Fertile Women for Hypothyroidism 337
• Iodine Deficiency in Pregnancy 338
• The Radioactive Iodine Shortage 339
• Potassium Iodide in the Age of Nuclear Reactors and Terrorism 339

Appendix A: Thyroid Links on the Web 343
Appendix B: Links to Other Conditions Related to Thyroid Disease 346
Glossary 348
Supportive Literature 355
Index 359 

About the Author

• Kenneth Ain, M.D., is a professor of medicine and director of the Thyroid Oncology Program, University of Kentucky. He is also director of the Thyroid Cancer Research Laboratory at the VA Medical Center in Lexington, Kentucky. He founded and moderates the thyroid cancer patient education Yahoo group thyroidcancerhelp.
• M. Sara Rosenthal, Ph.D., is an associate professor of bioethics, University of Kentucky College of Medicine, and director of the University of Kentucky Program for Bioethics. Dr. Rosenthal has written more than thirty health books, including several on thyroid disease.

Product Details

• Paperback: 384 pages
• Publisher: McGraw-Hill; 2 edition (2011)
• Language: English
• ISBN-10: 0071743480
• ISBN-13: 978-0071743488
• Product Dimensions: 9 x 7.3 x 1 inches

List Price: $19.95 

 

Immunoendocrinology: Scientific & Clinical Aspects (Contemporary Endocrinology Series)

As illustrated by the chapters in this book, autoimmune disorders are diverse and the same. At the heart of these diseases are specific alleles of genes of the major histocompatibility complex favoring the targeting of specific antigens, with diseases differing in the specific alleles favoring or preventing autoimmunity. The fine balance between self tolerance and autoimmunity is upset by major mutations in a few families, and multiple polymorphisms in most families. Large scale genetic (research involving the screening of hundreds of thousands of newborns) and then immunologic prediction of many autoimmune disorders is now a reality for both families and the general population. With the exception of celiac disease, environmental factors essential for disease and contributing to the marked increase in many of these disorders are undefined. Despite our lack of comprehensive knowledge, multiple immunotherapeutic clinical trials are underway.

It is my hope that our current knowledge base for Immunoendocrinology presented here will prove sufficient to design and test preventive paradigms. Nevertheless, it is my belief that our current basic research knowledge, also presented here, is insufficient to be assured of disease prevention with current trials. Contained within each of the chapters are incomplete drafts of maps that should eventually lead to disease prevention for specific disorders that in combination provide a comprehensive draft of our knowledge and ignorance of the continent of autoimmunity.

- The Editor -

Contents

Part I Immunoendocrinology: Scientific and Clinical Aspects

• 1 Primer on Immunoendocrinology
• 2 Discovering Novel Antigens
• 3 Developing and Validating High Sensitivity / Specificity Autoantibody Assays
• 4 Characterizing T-Cell Autoimmunity
• 5 Metabolic Syndrome and Inflammation

Part II Syndromes

• 6 The Mouse Model of Autoimmune Polyglandular Syndrome Type 1
• 7 Autoimmune Polyendocrine Syndrome Type I: Man
• 8 IPEX Syndrome: Clinical Profile, Biological Features, and Current Treatment
• 9 Autoimmune Polyendocrine Syndrome Type 2: Pathophysiology, Natural History, and Clinical Manifestations
• 10 Drug-Induced Endocrine Autoimmunity
• Part III Specific Dis eases
• 11 The BB Rat
• 12 Immunopathogenesis of the NOD Mouse
• 13 Virus-Induced Type 1 Diabetes in the Rat
• 14 Autoimmune Pathology of Type 1 Diabetes
• 15 Genetics of Type 1 Diabetes
• 16 Epidemiology of Type 1 Diabetes
• 17 Natural History of Type 1 Diabetes
• 18 Immunotherapy of Type-1 Diabetes: Immunoprevention and Immunoreversal
• 19 Latent Autoimmune Diabetes in Adults
• 20 Fulminant Type 1 Diabetes Mellitus
• 21 Insulin Autoimmune Syndrome (Hirata Disease)
• 22 Lessons from Patients with Anti-Insulin Receptor Autoantibodies
• 23 Islet and Pancreas Transplantation
• 24 Addison’s Disease
• 25 Animal Models of Autoimmune Thyroid Disease
• 26 Genetics of Thyroid Autoimmunity
• 27 Immunopathogenesis of Thyroiditis
• 28 Immunopathogenesis of Graves’ Disease
• 29 Graves’ Ophthalmopathy
• 30 Hypoparathyroidism
• 31 Premature Gonadal Insufficiency
• 32 Celiac Disease and Intestinal Endocrine Autoimmunity
• 33 Pituitary Autoimmunity

Index

About the Editor

• George S. Eisenbarth, University of Colorado Health Sciences Center, Barbara Davis Center for Childhood Diabetes, Aurora, CO, USA.

Product Details

• Hardcover: 579 pages
• Publisher: Humana Press; 1st Edition (2011)
• Language: English
• ISBN-10: 1603274774
• ISBN-13: 978-1603274777
• Product Dimensions: 10.1 x 7.1 x 1.6 inches

List Price: $189.00 

Greenstein: The Endocrine System at a Glance 3rd edition

The Endocrine System at a Glance provides a highly illustrated and unambiguous introduction to the basic principles and mechanisms of endocrinology and the key endocrine organs, followed by sections on reproductive and metabolic endocrinology. Clinical scenarios contextualize the basic science and illustrate how endocrine conditions present, are diagnosed, and are treated on the wards. 

This third edition:

• Includes new material on basic diagnostic tests used in the diagnosis of endocrine disorders.
• Features new material on cancer and endocrinology.
• Includes MCQs for each chapter.

The Endocrine System at a Glance is ideal for all medical students studying endocrinology and revising for final exams, as well as preparing for clinical attachments. The book is also suitable for those training in allied health professions and nurses specialising in endocrinology. 

 

Contents 

Part 1. Fundamentals.

• 1. Introduction.
• 2. Chemical transmission.
• 3. Mechanisms of hormone action: I Membrane receptors.
• 4. Mechanisms of hormone action: II Intracellular receptors.
• 5. The hypothalamus and pituitary gland.
• 6. Gonadotrophin-releasing hormone: a peptide hormone.
• 7. Principles of feedback control.
• 8. Endocrine function tests.

Part 2. Growth.

• 9. Growth: I Cellular growth factors.
• 10. Growth: II Normal growth.
• 11. Growth: III Growth hormone.
• 12. Growth: IV Pathophysiology.

Part 3. Thyroid.

• 13. Thyroid: I Thyroid gland and thyroid hormones.
• 14. Thyroid: II Thyroid hormone secretion and action.
• 15. Thyroid: III Thyroid pathophysiology.

Part 4. Adrenals and autoimmunity.

• 16. Adrenal gland: I Adrenal medulla.
• 17. Adrenal gland: II Adrenocortical hormones.
• 18. Adrenal gland: III Adrenocorticotrophic hormone (ACTH).
• 19. Adrenal gland: IV Cortisol and androgens.
• 20. Adrenal gland: V Aldosterone.
• 21. Adrenal gland: VI Pathophysiology.
• 22. Endocrine autoimmunity.

Part 5. Sexual differentiation and development.

• 23. Sexual differentiation and development: I Introduction.
• 24. Sexual differentiation and development: II Puberty.

Part 6. Female reproduction.

• 25. Female reproduction: I Menstrual cycle.
• 26. Female reproduction: II Ovarian steroids.
• 27. Female reproduction: III Pregnancy.
• 28. Female reproduction: IV Parturition and lactation.
• 29. Female reproduction: V Pathophysiology.
• 30. Female reproduction: VI Contraception.

Part 7. Male reproduction.

• 31. Male reproduction: I The testis.
• 32. Male reproduction: II Actions of androgens.
• 33. Male reproduction: III Pathophysiology.

Part 8. Posterior pituitary hormones, salt and water balance and hypertension.

• 34. Oxytocin.
• 35.Vasopressin.
• 36. Renin–angiotensin–aldosterone system.
• 37. Endocrine hypertension.

Part 9. Metabolic endocrinology: Pancreas and gastrointestinal tract.

• 38. Insulin: I The pancreas and insulin secretion.
• 39. Insulin: II Insulin action.
• 40. Insulin: III Type I diabetes mellitus.
• 41. Insulin: IV Type 2 diabetes mellitus.
• 42. Glucagon.
• 43. Gastrointestinal hormones.

Part 10. Metabolic endocrinology: Energy homoeostasis and obesity.

• 44. Energy homoeostasis: I Summary.
• 45. Energy homoeostasis: II Central control.
• 46. Obesity: I Causes of obesity.
• 47. Obesity: II Cardiovascular and respiratory complications.
• 48. Obesity: III Insulin resistance and endocrine complications.

Part 11. Calcium and metabolic bone disease.

• 49. Calcium: I Parathyroid hormone (PTH).
• 50. Calcium: II Calcitonin.
• 51. Calcium: III Vitamin D.
• 52. Bone remodelling.
• 53. Metabolic bone disease: I Paget’s disease.
• 54. Metabolic bone disease: II Primary osteoporosis.
• 55. Metabolic bone disease: III Secondary osteoporosis.

Part 12 Self assessment.

• MCQs.
• Answers.

Glossary.

Index.

Product Details

• Paperback: 144 pages
• Publisher: Wiley-Blackwell; 3 edition (September 13, 2011)
• Language: English
• ISBN-10: 1444332155
• ISBN-13: 978-1444332155
• Product Dimensions: 10.7 x 8.6 x 0.4 inches

List Price: $37.95 

 

Katsilambros: Atlas of the Diabetic Foot 2nd Edition

Diabetes mellitus is a common disease all over the world and its frequency is steadily increasing. The availability of a wide variety of treatment options results in improvement or even normalization of hyperglycemia as well as of the accompanying metabolic disorders. However people with diabetes continue to suffer from the complications of the disease.

Diabetic foot-related problems occur frequently and may have serious consequences. Amputations at different anatomical levels are the most serious of them.

The present Atlas represents a systematic description of the many different foot lesions, which are often seen in diabetic patients. Each fi gure corresponds to a case treated in our Diabetes Centre in the Athens University Medical School. Our patients are evaluated and treated in collaboration with the Orthopedic Department as well as with other specialists depending upon individual needs. A short text, which follows each illustration, describes the history of the patient, the physical signs observed, the approach of treatment, and is followed by a short comment.

It is no exaggeration to state that the new (second) edition of this book resulted from the marked success of the first edition. It must also be noted that the problems of the diabetic foot continue to be a major and very serious concern of every society in the world, even those with the best healthcare systems.

This new edition has been enriched with a relatively large number of representative pictures as well as new information. This work has been achieved through the enormous efforts of my colleagues, co-authors of the book, as well as through the technical help of the publisher.

It is hoped that this Atlas will be of assistance, as a reference guide and a teaching instrument, not only to diabetologists and surgeons, but also to all doctors involved in the treatment of diabetic patients. This book might help them not only to recognize and to treat the diabetic foot lesions, but also to prevent them.

- The Authors -

Key Features

• 520 colour photographs, graphs, tables and imaging studies.
• Educational examples taken from genuine case reports.
• A reference guide for identifying patients at risk for foot problems.
• Illustration of common problems such as neuropathic and neuroischaemic ulcers, ischaemia and infection.
• Introduction to new technologies and bioengineered materials used for the treatment of foot ulcers.

Contents

• Acknowledgments, vi
• Preface to the Second Edition, vii
• Preface to the First Edition, viii
• 1 Introduction, 1
• 2 Diabetic Neuropathy, 11
• 3 Anatomic Risk Factors for Diabetic Foot Ulceration, 21
• 4 Other Foot-Related Risk Factors, 48
• 5 Skin and Systemic Diseases with Manifestations in the Feet, 62
• 6 Neuropathic Ulcers, 74
• 7 Peripheral Vascular Disease, 91
• 8 Ischemic and Neuro-Ischemic Ulcers and Gangrene, 106
• 9 Heel Ulcers, 137
• 10 Charcot Foot, 148
• 11 Infections, 169
• 12 Methods of Prevention, 194
• 13 Methods of Ulcer Healing, 200
• 14 Amputations, 224
• Appendix, 243
• Index, 244

About the Authors 

• Nicholas Katsilambros MD, Professor in Internal Medicine Athens University Medical School Eygenideio Hospital and Research Laboratory “Christeas Hall” Athens, Greece.
• Eleftherios Dounis MD, FACS, Director Orthopedia Department Laiko General Hospital Athens, Greece. 
• Konstantinos Makrilakis MD, MPH, PhD, Assistant Professor in Internal Medicine Athens University Medical School 1st Department of Propaedeutic Medicine Laiko General Hospital Athens, Greece.
• Nicholas Tentolouris MD, Asssistant Professor 1st Department of Propaedeutic Medicine Athens University Medical School Laiko General Hospital Athens, Greece.
• Panagiotis Tsapogas MD, Medical and Diabetes Department Medical Bioprognosis Corfu, Greece. 

Product Details

• Hardcover: 260 pages
• Publisher: Wiley-Blackwell; 2 edition (May 11, 2010)
• Language: English
• ISBN-10: 1405191791
• ISBN-13: 978-1405191791
• Product Dimensions: 9.8 x 7.3 x 0.8 inches

List Price: $162.95 

 

Thompson: The Low-Starch Diabetes Solution: Six Steps to Optimal Control of Your Adult-Onset (Type 2) Diabetes

Until recently, doctors thought adult-onset diabetes was the same as childhood diabetes—that both were caused by lack of insulin. In the 1980s, scientists made the remarkable discovery that they’re entirely different diseases. Whereas kids with diabetes lack insulin, most adult-onset diabetics make plenty of insulin—often more than normal. The problem is that their bodies lose sensitivity to it. Now doctors refer to the disease that young people get as type 1 diabetes and to the kind that middle-aged adults get as type 2-diabetes. This book is for people with adult-onset, or type 2 diabetes.

In times past, the diagnosis of diabetes had tragic implications. Children and young adults with type 1 diabetes often wasted away and died from it. Insulin, when it came along in the 1920s, was the miracle drug for these patients. It allowed them to live normal lives. In those days, the troubles of middle-aged and older folks with type 2 diabetes seemed minor compared with young people with type 1 diabetes. Adult-onset diabetics could live for years with hardly any treatment at all. They could usually get their blood sugar down to reasonable levels by just taking some pills and watching their diet. Doctors rarely prescribed insulin for these patients; they fi gured it wasn’t worth the trouble.

In the 1990s, new research showed that while patients with type 2 diabetes rarely died as a direct result of their diabetes, their mildly elevated blood sugar levels—if these went on long enough—could result in damage to their eyes, kidneys, and blood vessels, and the attendant increase in heart attack rate was alarming. As a result, doctors started taking adult-onset diabetes more seriously, treating it as they would type 1 diabetes, using stronger pills and insulin when necessary to get blood sugar levels as close to normal as possible.

In 2008, researchers released the results of two large studies on the effects of this more vigorous approach to treating adult-onset diabetes. The results were disappointing. Heavier doses of insulin helped patients avoid eye and kidney damage but did little to reduce the rate of heart attacks. What worked for patients with juvenile diabetes didn’t work as well for people with adult-onset diabetes. Those results are not really surprising, considering that type 2 diabetes is a completely different disease from type 1. It has different causes, results in different complications, and requires a different approach to treatment. The goal of treating type 1 diabetes is simple: replace the missing insulin. Type 2 diabetes is more complicated. The body becomes resistant to the effects of insulin, which not only raises blood sugar but brings on cholesterol, blood pressure, and weight problems that cause as much trouble as the high blood sugar does. This often requires a multipronged approach to treatment.

The good news is that you can live to a ripe old age without suffering any health problems from your type 2 diabetes. When the nineteenth-century sage George Bernard Shaw said the secret to good health is to get a chronic disease and take good care of it, he might as well have been talking about adult-onset diabetes. When you do what you need to do to treat it, you reverse many of our modern lifestyle’s harmful effects on your health and general well-being. Indeed, you might find yourself feeling better than you have for years.

This book will give you six simple steps to follow that should give you excellent control of your type 2 diabetes. First, however, it is important to understand the logic behind its treatment. Once you see what brought on your condition, you will know exactly what you need to do to reverse it.

Key Features

• An innovative program that challenges current ADA guidelines—not available in any other book.
• Tips on starch-free cooking and easy-to-make low-starch recipes by Dana Carpender, author of the bestselling 15-Minute Low-Carb Recipes.
• A seven-day, easy-to-follow menu plan.
• A way to lose weight, regain vitality, and reduce medication.

Contents

Part One: The Toxin

• Chapter 1: A Gift From the Mediterranean
• Chapter 2: Lowering Blood Sugar the Old-Fashioned Way
• Chapter 3: Glycemic Load: The New Old Way
• Chapter 4: The Culprit
• Chapter 5: What Starch Does to Your Body
• Chapter 6: Starch's Slippery Mimic
• Chapter 7: The Starch-Vulnerable Individual: Insulin Resistance
• Chapter 8: Things That Get Better When You Eliminate Starch
• Chapter 9: Why We Are Addicted

Part Two: Six Steps to Optimal Control

• Chapter 10: Step One: Eliminate Starch
• Chapter 11: Step Two: Inhibit Starch Absorption
• Chapter 12: Step Three: Sensitize Your Muscles to Insulin
• Chapter 13: Step Four: Sensitize Your Liver to Insulin
• Chapter 14: Step Five: Make Up Any Insulin Deficit With Insulin
• Chapter 15: Step Six: Optimize Your Cholesterol and Blood Pressure

Part Three: Part 3 Low-Starch Cuisine: Discovering a Tastier Way to Eat 

• Chapter 16: Starch Substitutes That Taste Better Than Starch
• Chapter 17: The Art of Baking With Starch-Free Flours
• Chapter 18: 7 Days of Low-Starch Menus

Appendices 

• Appendix A: Metric Conversion Factors
• Appendix B: References
• Appendix C: Websites and Suggested Reading

Index

About the Author

• Rob Thompson, M.D. (Seattle, WA) is a board-certified cardiologist in private practice who has counseled patients with high cholesterol, diabetes, and heart disease for more than 25 years. He is on staff at Swedish Hospital Medical Center in Seattle and is the author of The New Low-Carb Way of Life as well as The Glycemic-Load Diet.

Product Details

• Paperback: 256 pages
• Publisher: McGraw-Hill; 1 edition (October 1, 2010)
• Language: English
• ISBN-10: 0071621504
• ISBN-13: 978-0071621502
• Product Dimensions: 8.9 x 5.9 x 0.7 inches

List Price: $16.95 

 

Bilous: Handbook of Diabetes 4th Edition with CD

Over three editions the Handbook of Diabetes has built a reputation as an essential practical manual on the assessment and management of patients with diabetes. Previously written by Gareth Williams and John Pickup, the book has been completely revised by Rudy Bilous and Richard Donnelly to reflect recent changes in diabetes treatment and care. It contains information on the new IFCC units for measuring blood glucose and the latest drugs being used to combat diabetes, as well as alternative methods of insulin delivery.

The book has been fully updated and redesigned to make it even more user-friendly, and contains case histories, practice points, and landmark clinical trials highlighted in color in each chapter where appropriate. It also features an entirely new set of clinical photographs, and all 250 images from the book can be downloaded from the companion CD for use in presentations.

 

The Handbook of Diabetes is the ideal practical handbook for all health professionals with an interest in diabetes care.

Contents 

Part 1: Introduction to diabetes.

• 1 Introduction to diabetes.
• 2 History of diabetes.
• 3 Diagnosis and classifi cation of diabetes.
• 4 Public health aspects of diabetes.
• 5 Normal physiology of insulin secretion and action.
• 6 Epidemiology and aetiology of type 1 diabetes.
• 7 Epidemiology and aetiology of type 2 diabetes.
• 8 Other types of diabetes.

Part 2: Metabolic control and complications.

• 9 Diabetes control and its measurement.
• 10 Management of type 1 diabetes.
• 11 Management of type 2 diabetes.
• 12 Diabetic ketoacidosis, hyperglycaemic hyperosmolar state and lactic acidosis.
• 13 Hypoglycaemia.
• 14 Control and complications.
• 15 Diabetic eye disease.
• 16 Diabetic nephropathy.
• 17 Diabetic neuropathy.
• 18 Blood lipid abnormalities.
• 19 Hypertension in diabetes.
• 20 Macrovascular disease in diabetes.
• 21 Foot problems in diabetes.
• 22 Sexual problems in diabetes.
• 23 Gastrointestinal problems in diabetes.
• 24 Skin and connective tissue disorders in diabetes.
• 25 Psychological and psychiatric problems in diabetes.

Part 3: The spectrum and organisation of diabetes care.

• 26 Specific circumstances that affect diabetes control.
• 27 Pregnancy and diabetes.
• 28 Diabetes in childhood and adolescence.
• 29 Diabetes in old age.
• 30 Diabetes and lifestyle.
• 31 Organisation of diabetes care: diabetes specialist nursing, diabetes education and general practice.
• 32 Future directions in diabetes management and research.

Index.

About the Authors 

• Rudy Bilous MD, FRCP, Professor of Clinical Medicine, Newcastle University; Hon. Consultant Endocrinologist, South Tees Foundation Trust, Middlesbrough, UK.
• Richard Donnelly MD, PhD, FRCP, FRACP, Head, School of Graduate Entry Medicine and Health, University of Nottingham; Hon. Consultant Physician, Derby Hospitals NHS Foundation Trust, Derby, UK. 

Book Review 

"A significant feature of the book is the provision of a CD ROM which allows the purchaser to download all  269 images from the book for their own use and teaching purposes. This will be particularly useful to students and pracitioners in training who are increasingly looking for good quality material to illustrate their own presentations." (Practical Diabetes International, 2010) 

Product Details

• Paperback: 248 pages
• Publisher: Wiley-Blackwell; 4 edition (2011)
• Language: English
• ISBN-10: 1405184094
• ISBN-13: 978-1405184090
• Product Dimensions: 10.7 x 8.5 x 0.6 inches

List Price: $89.95 

 

Holt: Textbook of Diabetes 4th Edition

Over three editions the Textbook of Diabetes has built a reputation as a book that is extremely well-organized and easy to navigate, with exceptional illustrations and an excellent blend of clinical and scientific content. Previously edited by John Pickup and Gareth Williams this fourth edition has four brand new editors from across the globe.

The editors have assembled an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world.

The new Textbook of Diabetes has been restructured into 12 parts in one accessible volume and is designed with the busy diabetes care team in mind. As well as retaining the elements that have made it such a popular brand, such as the outstanding full colour illustrations and text design, the new edition sees even greater emphasis on the clinical aspects of diabetes, with new chapters on managing patients with diabetes, the treatment of diabetes, and the delivery and organization of diabetes care, including:

• Non-insulin parenteral therapies
• New technologies for insulin administration and glucose monitoring
• The role of the multidisciplinary team

 

There is also a companion website accompanying the book containing essential bonus material such as:  

• Over 150 interactive MCQ's to help you improve and test your clinical knowledge.
• All 500 figures from the book in a downloadable format to use in slides and presentations.
• Chapter pdfs and chapter references with full links to PubMed.

If you want a modern, well-illustrated, international guide to diabetes this is the ideal reference book for you.

Contents

Part 1 Diabetes in its Historical and Social Context.

• 1 The History of Diabetes Mellitus (Robert B. Tattersall).
• 2 The Classifi cation and Diagnosis of Diabetes (K. George M.M. Alberti).
• 3 Epidemiology of Type 1 Diabetes (Lars C. Stene, Valma Harjutsalo, Elena Moltchanova & Jaakko Tuomilehto).
• 4 Epidemiology of Type 2 Diabetes (Ronald C.W. Ma & Peter C.Y. Tong).
• 5 The Global Burden of Diabetes (Mohammed K. Ali, Mary Beth Weber & K.M. Venkat Narayan).

Part 2 Normal Physiology.

• 6 Islet Function and Insulin Secretion (Peter M. Jones & Shanta J. Persaud).
• 7 Insulin Action (Xuxia Wu & W. Timothy Garvey).
• 8 Control of Weight: How Do We Get Fat? (George A. Bray).

Part 3 Pathogenesis of Diabetes.

• 9 Type 1 Diabetes.
• Autoimmune Type 1 Diabetes (Ahmed J. Delli, Helena Elding Larsson, Sten-A. Ivarsson & Åke Lernmark).
• Other Disorders with Type 1 Phenotype (Alice P.S. Kong & Juliana C.N. Chan).
• 10 Abnormalities of Insulin Secretion and β-Cell Defects in Type 2 Diabetes (Mazen Alsahli & John E. Gerich).
• 11 Insulin Resistance in Type 2 Diabetes (Hannele Yki-Järvinen).
• 12 The Genetics of Type 2 Diabetes: From Candidate Gene Biology to Genome-Wide Studies (Martine Vaxillaire & Philippe Froguel).
• 13 Metabolic Disturbances in Diabetes (Adrian Vella & Robert A. Rizza).
• 14 Obesity and Diabetes (Hans Hauner).

Part 4 Other Types of Diabetes.

• 15 Monogenic Causes of Diabetes (Angus Jones & Andrew T. Hattersley).
• 16 Drug-Induced Diabetes (Neil J.L. Gittoes, John Ayuk & Robin E. Ferner).
• 17 Endocrine Disorders that Cause Diabetes (Neil A. Hanley).
• 18 Pancreatic Diseases and Diabetes (Ranjit Unnikrishnan & Viswanathan Mohan).

Part 5 Managing the Patient with Diabetes.

• 19 Clinical Presentations of Diabetes (Ee Lin Lim & Roy Taylor).
• 20 The Aims of Diabetes Care (Richard I.G. Holt & Barry J. Goldstein).
• 21 Educating the Patient with Diabetes (Carolé Mensing & Barbara Eichorst).
• 22 Lifestyle Issues: Diet (Monika Toeller).
• 23 Lifestyle Issues: Exercise (Jane E. Yardley, Angela Alberga, Glen P. Kenny & Ronald J. Sigal).
• 24 Social Aspects of Diabetes (Brian M. Frier & Mark W.J. Strachan).
• 25 Monitoring Diabetes (Andrew J. Farmer).
• 26 Drug Therapy: Special Considerations in Diabetes (Bernard M.Y. Cheung & Robin E. Ferner).

Part 6 Treatment of Diabetes.

• 27 Insulin and Insulin Treatment (Stephen Gough & Parth Narendran).
• 28 New Technologies for Insulin Administration and Glucose Monitoring (Howard Wolpert & Judy Shih).
• 29 Oral Antidiabetic Agents (Clifford J. Bailey & Andrew J. Krentz).
• 30 Non-Insulin Parenteral Therapies (Jens Juul Holst, Sten Madsbad & Ole Schmitz).
• 31 How to Use Type 2 Diabetes Treatments in Clinical Practice: Combination Therapies (Joseph A. Aloi & Anthony L. McCall).
• 32 In-Hospital Treatment and Surgery in Patients with Diabetes (Maggie Sinclair Hammersley & June James).
• 33 Hypoglycemia in Diabetes (Philip E. Cryer).
• 34 Acute Metabolic Complications of Diabetes: Diabetic Ketoacidosis and Hyperosmolar Hyperglycemia (Troels Krarup Hansen & Niels Møller).

Part 7 Microvascular Complications in Diabetes.

• 35 Pathogenesis of Microvascular Complications (Ferdinando Giacco & Michael Brownlee).
• 36 Diabetic Retinopathy (Peter H. Scanlon).
• 37 Diabetic Nephropathy (Sally M. Marshall & Allan Flyvbjerg).
• 38 Diabetic Peripheral Neuropathy (Dan Ziegler).

Part 8 Macrovascular Complications in Diabetes.

• 39 The Pathogenesis of Macrovascular Complications Including Atherosclerosis in Diabetes (Riccardo Candido, Mark E. Cooper & Karin A.M. Jandeleit-Dahm).
• 40 Cardiovascular Risk Factors: Hypertension (Peter M. Nilsson) and Dyslipidemia: Diabetes Lipid Therapies (Adie Viljoen & Anthony S. Wierzbicki).
• 41 Congestive Heart Failure (Inga S. Thrainsdottir & Lars Rydén).
• 42 Cerebrovascular Disease (Colum F. Amory & Jesse Weinberger).
• 43 Peripheral Vascular Disease (Henrik H. Sillesen).

Part 9 Other Complications of Diabetes.

• 44 Foot Problems in Patients with Diabetes (Andrew J.M. Boulton).
• 45 Sexual Function in Men and Woman with Diabetes (David Price).
• 46 Gastrointestinal Manifestations of Diabetes (Adil E. Bharucha & Michael Camilleri).
• 47 The Skin in Diabetes (Graham R. Sharpe & Paul D. Yesudian).
• 48 Bone and Rheumatic Disorders in Diabetes (Andrew Grey & Nicola Dalbeth).
• 49 Psychologic Factors and Diabetes (Christopher M. Ryan).
• 50 Diabetes and Infections (Clive S. Cockram & Nelson Lee).

Part 10 Diabetes in Special Groups.

• 51 Diabetes in Childhood (Christine Chan & Marian Rewers).
• 52 Diabetes in Adolescence and Transitional Care (Debbie Kralik & Maria Kambourakis).
• 53 Diabetes in Pregnancy (Anne Dornhorst & Anita Banerjee).
• 54 Diabetes in Old Age (Alan J. Sinclair).
• 55 Psychiatric Disorders and Diabetes (Robert C. Peveler & Richard I.G. Holt).

Part 11 Delivery and Organization of Diabetes Care.

• 56 The Role of Community and Specialist Services (Jane Overland, Margaret McGill & Dennis K. Yue).
• 57 The Role of the Multidisciplinary Team (Wing-Yee So & Juliana C.N. Chan).
• 58 Models of Diabetes Care Across Different Resource Settings (Naomi S. Levitt, Bob Mash, Nigel Unwin, Jean Claude Mbanya, Jae-Hyoung Cho & Kun-Ho Yoon).

Part 12 Future Directions.

• 59 Future Drug Treatment for Type 1 Diabetes (Helena Elding Larsson, Ahmed J. Delli, Sten-A. Ivarsson & Åke Lernmark).
• 60 Future Drug Treatments for Type 2 Diabetes (Clifford J. Bailey).
• 61 Other Future Directions.
• Stem Cell Therapy in Diabetes (Shuibing Chen, Jayaraj Rajagopal, Qiao Zhou & Douglas A. Melton).
• Islet Transplantation (Angela Koh, Peter Senior & A.M. James Shapiro).
• Gene Therapy (Andreea R. Barbu & Nils Welsh).
• 62 Future Models of Diabetes Care (Robert A. Gabbay & Alan M. Adelman).

Index.

About the Authors 

• Richard I.G. Holt, MA, MB BChir, PhD, FRCP, FHEA, Professor in Diabetes & Endocrinology, Developmental Origins of Health and Disease Division, University of Southampton School of Medicine, Southampton, UK
• Clive S. Cockram, MB BS, BSc, MD (Lond), FRCP, FRACP, FHKAM (Med), Emeritus Professor of Medicine, Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China
• Allan Flyvbjerg, MD, DMSc, Professor of Clinical Endocrinology and Chair, Department of Endocrinology and Internal Medicine, The Medical Research Laboratories, Aarhus University Hospital - Aarhus University, Aarhus, Denmark
• Barry J. Goldstein, MD, PhD, FACP, FACE, Therapeutic Area Head, Diabetes and Obesity, Vice President, Clinical Research, Metabolism, Merck Research Laboratories, Rahway, NJ, USA

Book Reviews 

• "This sizeable book has been condensed into one volume with 12 sections and 62 chapters, each clearly laid out with colour diagrams, tables and a very useful summary of key points." (Diabetes Update, 1 April 2011) 
• "Overall, the 4th edition of Textbook of Diabetes is likely to be most useful to health-care providers who are involved in diabetes disease state management. The evidence-based Clinical Practice Recommendations, developed by the American Diabetes Association and revised to include up-to-date research findings on an annual basis, are additional relevant and important resources for health-care providers and will complement the use of this textbook." (The Annals of Pharmacotherapy, January 2011) 
• "A companion website (access included) contains all the content as well as multiple choice questions for each chapter, reference lists with external links, and figures from the book for downloading." (Book News, September 2010) 
• "The 4th edition of the 'Textbook of Diabetes' is a complete reference guide to all aspects of diabetes care and a worthy successor to the previous editions. It will be an invaluable addition to any medical library or diabetes centre." (Practical Diabetes International, November 2010) 
• "In common with previous editions there is an exceptional list of expert international contributors who have written chapters that are all well researched, easy to read and comprehensively referenced with the key points neatly summarised in bullet points at the beginning of each chapter. The book is also beautifully illustrated with numerous full colour figures and photographs." (Practical Diabetes International, November 2010)

Product Details

• Hardcover: 1144 pages
• Publisher: Wiley-Blackwell; 4 edition (2011)
• Language: English
• ISBN-10: 1405191813 
• ISBN-13: 978-1405191814
• Product Dimensions: 11.1 x 8.9 x 2.2 inches

List Price: $299.95 

 

Raine: Practical Endocrinology and Diabetes in Children 3rd Edition

Practical Endocrinology and Diabetes in Children is the ideal bench-side companion for the practising paediatrician and endocrinologist, bridging the gap between large reference books and short reviews of aspects of endocrinology. 

 
This third edition contains a variety of new features such as key web links, guidelines, case studies illustrating diagnostic difficulties which will help all those studying for postgraduate examinations such as the MRCPCH.
The book provides a highly clinical, concise and up-to-date account of paediatric endocrinology and diabetes in a clear and user friendly format. There are sections on how to deal with emergencies, as well as information on potential pitfalls, controversial areas and future developments.
 
Practical Endocrinology and Diabetes in Children is an essential guide for trainee paediatricians, paediatric endocrinologists and diabetologists as well as diabetes and endocrinology nurse specialists.

Contents

• Preface.
• Acknowledgements.
• Abbreviations.
• 1 Diabetes Mellitus.
• 2 Hypoglycaemia.
• 3 Short Stature.
• 4 Tall Stature.
• 5 Puberty.
• 6 Thyroid Disorders.
• 7 Disorders of Sex Development and Common Genital Anomalies.
• 8; Adrenal disorders.
• 9 Salt and water balance.
• 10 Calcium and bone.
• 11 Obesity.
• 12 Endocrine effects of cancer treatment.
• Appendix 1 Growth and BMI charts.
• Appendix 2 CAH therapy card.
• Index.

About the Authors 

• Joseph E. Raine, MD, FRCPCH, DCH, Consultant Paediatrician, Whittington Hospital, London, UK.
• Malcolm D. C. Donaldson, MD, FRCP, DCH, Senior Lecturer in Child Health and Honorary Consultant Paediatric Endocrinologist, Royal Hospital for Sick Children, Glasgow, UK.
• John W. Gregory, MBChB, MD, FRCP, DCH, FRCPCH, Professor of Paediatric Endocrinology, Cardiff University, Cardiff, UK.
• Guy Van Vliet, Professor of Paediatrics and Chief of Endocrinology, Sainte-Justine Hospital, Montreal, Canada. 

Product Details

• Hardcover: 272 pages
• Publisher: Wiley-Blackwell; 3 edition (2011)
• Language: English
• ISBN-10: 1405196343
• ISBN-13: 978-1405196345
• Product Dimensions: 9.8 x 7.5 x 0.8 inches

List Price: $99.95 

 

Byrne: The Metabolic Syndrome 2nd edition

The Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. This book explains the aetiology, pathogenesis and clinical treatment of all risk factors as well as the relationship with diabetes, non alcoholic fatty liver disease, polycystic ovary syndrome and coronary heart disease.

 

The Metabolic Syndrome  has been further improved from the 1^st edition that was highly commended in 2006 Annual British Medical Association medical books competition.  All chapters from the first edition are fully updated and this new edition contains an increase in international contributions and five new chapters on:

• Childhood obesity and metabolic syndrome
• Bariatric surgery for obesity
• Fitness
• Brain insulin resistance and appetite
• The nature of the insulin resistance seen in metabolic syndrome.

 

This brand new edition of The Metabolic Syndrome will be an indispensable resource for all clinical researchers, physicians and scientists requiring detailed up-to-date information on the metabolic syndrome to further their own research or to treat and manage the syndrome and its complications. Specifically, the text will be of particular relevance to those involved and working in the fields of diabetes, endocrinology, obesity, cardiology, vascular disease and hepatology.

About the Authors

• Christopher Byrne trained as a physician and clinical scientist at Cardiff, Cambridge and Stanford Universities. After Medical Research Council clinical science fellowships he was appointed Professor of Endocrinology & Metabolism at Southampton University Hospitals Trust, UK. He is an academic diabetologist with clinical and molecular research interests in the pathogenesis of the metabolic syndrome, and the mechanisms linking metabolic syndrome with type 2 diabetes and cardiovascular disease. His publications span a range of disciplines from epidemiological to gene expression studies. He has had 112 articles published.
• Sarah Wild trained in medicine in London and Cambridge and subsequently received training in epidemiology at Stanford University and the London School of Hygiene and Tropical Medicine. She is currently senior lecturer in epidemiology at the University of Edinburgh. Her research interests include the global burden of diabetes and metabolic syndrome and cardiovascular epidemiology.She has had 31 articles published.

Product Details

• Hardcover: 384 pages
• Publisher: Wiley-Blackwell; 2 edition (August 23, 2011)
• Language: English
• ISBN-10: 1444336584
• ISBN-13: 978-1444336580
• Product Dimensions: 9.8 x 7.6 x 1 inches

List Price: $116.95