In the last decades, investments in basic research have yielded extensive knowledge about the many and complex processes involved in the development of an organism. Since human pluripotent stem cells were first isolated, research on stem cells has received much public attention, both because of its extraordinary promise and because of relevant legal and ethical issues. Regenerative medicine is classified into cell therapy that does not require a scaffold and tissue engineering that requires a scaffold and bioactive substances such as growth factors; though both need adult stem cells. Bioengineers, life scientists, and physicians across all specialties are synergistically coupling expertise in areas such as cell culture technology, tissue transfer, cell differentiation, angiogenesis, computer modeling, and polymer chemistry to use adipose tissue as a base for regenerative medicine.
On November 2008, during a meeting of Yves-Gérard Illouz and Aris Sterodimas in Rio de Janeiro, Brazil, the idea to write a book focusing on adipose stem cells and their role in regenerative medicine was born. This book is the most up-to-date text on regenerative medicine based on adipose stem cells. There are 24 chapters by international experts with the newest techniques explained in detail. Bioengineers, life scientists, and physicians from Brazil, Canada, France, Germany, Greece, Indonesia, Israel, Italy, Korea, Japan, Switzerland, Turkey, United Arabic Emirates, UK, and USA joined forces in order to ensure the reader is provided information both about the basic biology of adipose stem cells, and their therapeutic potential. This book contains chapters focused on the applications of adipose stem cells on specific fields, like cardiology, orthopedic surgery, neurology, urology, otolaryngology, plastic and reconstructive surgery, organ transplantation, and dentistry. Also included are chapters on adipose stem cells as therapeutic delivery tools for gene therapy, in the field of pharmacology and obesity. The science represented in this book focuses exclusively on scientific publications, paying extreme attention to the safety and ethics considerations for developing adipose stem cell-based therapies.
The compilation of this book on the latest advances in the field of adipose stem cell research required the participation of many individuals. We wish to sincerely thank all the authors for contributing to this book. We would like to acknowledge, in particular, the contribution of Mrs. Mahalakshmi and the Springer team for the meticulous type-editing of the chapter in this book and Mrs. Ellen Blasig from Springer-Verlag for her continuous support since we embarked on this project in January 2010.
- The Editors -
Contents
- 1 Cellular and Molecular Aspects of Adipose Tissue
- 2 Isolation of Stem Cells from Human Adipose Tissue: Technique, Problems, and Pearls
- 3 Principles of Liposuction
- 4 Clinical Applications of Liposuction
- 5 Principles of Autologous Fat Transplantation
- 6 Clinical Applications of Autologous Fat Transplantation
- 7 Adipose Stem Cells: From Liposuction to Adipose Tissue Engineering
- 8 Storage of Adipose Stem Cells
- 9 Engineered Scaffolds and Matrices: Tailored Biomaterials for Adipose Stem Cell Engineering
- 10 Fundamentals and Principles of Biomolecules in Adipose Stem Cell Engineering
- 11 Gene Therapy Used for Adipose Stem Cell Engineering Applications
- 12 Stem Cells from Human Adipose Tissue: A New Tool for Pharmacological Studies and for Clinical Applications
- 13 Role of Adipose Stem Cells Therapy in Obesity
- 14 Stem Cell Based Cardioregeneration and Adipose Tissue
- 15 Adipose Stem Cell Engineering: Characterization and Current Application in Neurological Tissue Repair
- 16 Adipose Stem Cell Engineering: Clinical Applications in Plastic and Reconstructive Surgery
- 17 Orthopedic Use of Adipose-Derived Stem Cells
- 18 Adipose-Derived Stem Cells: Characterization and Application in Urology
- 19 Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology
- 20 Adipose Stem Cell Technologies for Tissue Regeneration in Dentistry
- 21 Adipose Stem Cells, Tissue Engineering, and Solid Organ Transplantation and Regeneration
- 22 Industrial Approaches to Adipose Stem Cells Engineering
- 23 Future Research in Adipose Stem Cell Engineering
- 24 Conclusions and Future Directions
- Index
About the Editors
- Prof. Yves-Gérard Illouz, Plastic Surgery, Department, Saint Louis Hospital, Avenue Claude-Vellefaux, Paris, France.
- Prof. Aris Sterodimas, Plastic and Reconstructive Surgery, Department, IASO General Hospital, 264 Mesogeion Avenue, Athens, Greece.
Foreword
It has been said that man is entering a new era of discoveries, the truly first revolution since the discovery and harnessing of fire. In a word: biotechnology. This vast and growing field of knowledge presents to us, on a daily basis, inventions that only a few years ago would have seemed to be taken out of a story by Jules Verne. The correlated sciences that surround biotechnology stretch from engineering to computers, from biology to nanotechnology. As physicians, we are challenged with new concepts and terminology that already are part of our lexicon. It is in this spirit that my fellow plastic surgeons, Drs. Illouz and Sterodimas, present to the medical reader the book Adipose Stem Cells and Regenerative Medicine.
Dr. Illouz is recognized as a pioneer in liposuction, and it is natural that, with his curious mind, he follows his interest in adipose tissues, immersing into the everexpanding discipline of cell culture and derivation. The promise of perpetuating and renovating whole tissues is leading us into a new era of medical practice, called regenerative medicine. Together with Dr. Sterodimas, a younger colleague, recently graduated from our school, Dr. Illouz stimulates our intellect, opening new vistas to an unknown future.
The authors are to be congratulated for this pioneering publication.
- By Ivo Pitanguy -
Product Details
- Hardcover: 290 pages
- Publisher: Springer; 1st Edition (October 28, 2011)
- Language: English
- ISBN-10: 3642200117
- ISBN-13: 978-3642200113
- Product Dimensions: 10.3 x 7.7 x 0.7 inches
List Price: $189.00