In the 12 years since the publication of the first edition of Urologie Surgical Pathology, great strides have been made in our understanding of urologic diseases. Many clinically important new histopathologic entities have been described or more fully defined in virtually every genitourinary organ. Numerous clinically important diagnostic and prognostic markers have entered routine practice, including alpha-methylacyl-CoA racemase, the most widely discussed biomarker in surgical pathology in this century. Genetic testing for the early detection of bladder and prostate cancer and the molecular classification of renal cell carcinomas has become increasingly important. This is an age of enlightenment in urologic surgical pathology, and we have attempted to capture the sense of excitement herein.
Our specialty of surgical pathology continues to evolve. The emergence of personalized medicine has created a paradigm shift in diagnostic and prognostic biomarker analysis. Diagnostic tests are now linked to individualized treatments. The dream of digital imaging is slowly being realized; high resolution images are now routinely captured and transmitted across the internet for multiple purposes. Central pathology review of clinical trial cases has become common practice, and central review protocols will likely be standardized in the near future. The accuracy of predictive outcome models for individual patients continues to be improved. New algorithms, nomograms, neural networks, and other models emerge virtually every month. Further, evidence-based practice with an emphasis on levels of scientific evidence is replacing the ‘intuitive’ practice of medicine, resulting in more consistent outcomes.
Throughout this renaissance in the classification and diagnosis of urologic diseases and in the prediction of individual patient outcome, the histopathologic examination of tissue and cells remains the gold standard. Today's surgical pathologist in any part of the world finds urologic specimens to be an increasingly important part of everyday sign-out. The expectation for excellence in diagnosis remains very high. It is with this understanding that we have produced our second edition.
This book is intended chiefly for use by surgical pathologists in their daily practice. The numerous comments and suggestions from readers of the first edition have been carefully considered and incorporated into the current effort. The text has expanded more than 30%, and the number of fullcolor illustrations now exceeds 1200. Two new chapters have been added (Urine Cytology and Fine Needle Aspiration of the Kidney) to reflect increasing emphasis on cellular diagnosis in urologic pathology. We have remained true to our purpose of providing a framework for comparison, evaluation, and integration into clinical practice of the evolving urologic diagnosis. The emphasis remains on the practical aspects of diagnostic pathology.
We are exceedingly grateful to our contributing colleagues for sharing their knowledge and experience. We continue to solicit constructive criticism to ensure greater usability in future editions.
David G. Bostwick, and Liang Cheng
Book Features
- Presents the practice-proven experience of today's authorities to enable you to diagnose with confidence.
- Limits coverage of general mechanisms of disease and anatomy to the most relevant information needed to fully comprehend the clinical picture.
- Includes boxed lists of types and causes of diseases, differential diagnosis, characteristic features of diseases, complications, classifications, and staging that help you quickly locate the specific information you need.
Website Features
- Consult the book from any computer at home, in your office, or at any practice location.
- Instantly locate the answers to your clinical questions via a simple search query.
- Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
- Images Browse a Library of all book images. Easily select, organize, and download your images into a presentation.
- Path Consult DDX Fundamentals Maximize clinical efficiency and productivity with Path Consult, an easy-to-use online resource that will help you quickly and easily confirm diagnoses.
New in this edition
- Includes access to a companion web site offering the complete contents of the book-fully searchable-for rapid consultation from anyplace with an Internet connection.
- Features a downloadable Online Image Collection that you can use to enhance your presentations.
- Presents two brand-new chapters covering urinary cytology and fine needle aspiration to keep you up to date.
- Covers newly described entities and application of ancillary study for precise diagnosis.
- Features integration of new molecular techniques and immunohistochemical analysis for differential diagnosis.
- Equips you with the latest recommended diagnostic approaches help you make the most informed decisions.
- Provides you with a critical review of the current classifications of cancer and disease.
- Features more than 1500 high-quality illustrations-in full color-providing a complete visual perspective of the conditions encountered in pathology.
Contents CHAPTER 1 - Non-neoplastic diseases of the kidney
- Embryologic development and normal structure
- Parenchymal maldevelopment and cystic diseases
- Vascular diseases
- Tubulointerstitial diseases
- Metabolic abnormalities and tubulointerstitial diseases
- Renal transplantation
- Ciclosporin and FK 506 nephrotoxicity
- Miscellaneous conditions
CHAPTER 2 - Neoplasms of the kidney
RENAL CELL TUMORS
- Papillary adenoma
- Oncocytoma
- Renal cell carcinoma
- Prognostic factors in renal cell carcinoma
- Metanephric tumors
- Nephroblastic tumors
- Mesenchymal tumors occurring mainly in children
- Mesenchymal tumors occurring mainly in adults
- Mixed mesenchymal and epithelial tumors
- Neuroendocrine tumors
- Hematopoietic and lymphoid tumors
- Germ cell tumors
- Metastatic tumors
CHAPTER 3 - Renal pelvis and ureter
- Development
- Anatomy
- Congenital malformations
- Non-neoplastic proliferative, metaplastic, and inflammatory lesions
- Neoplasms
CHAPTER 4 - Fine needle aspiration of the kidney
- Background to renal fine needle aspiration
- Normal elements
- Benign lesions
- Malignant lesions
- Future trends
CHAPTER 5 - Non-neoplastic disorders of the urinary bladder
- Embryology and anatomy
- Epithelial abnormalities
- Inflammation and infection
- Polyps and other mass lesions
- Mullerian lesions
- Malformations
CHAPTER 6 - Neoplasms of the urinary bladder
- Benign urothelial (transitional cell) neoplasms
- Flat intraepithelial lesions
- Urothelial (transitional cell) carcinoma
- Glandular neoplasms
- Squamous cell neoplasms
- Neural and neuroendocrine tumors
- Sarcomatoid carcinoma
- Soft tissue tumors
- Malignant melanoma
- Germ cell tumors
- Hematologic malignancies
- Metastatic tumors and secondary extension
CHAPTER 7 - Urine cytology
- Utility of urine cytology
- Normal components of urinary sediment
- Non-cellular components of urinary sediment
- Diagnostic criteria
- Urine cytology in renal transplant recipients
- Other benign conditions
- Cytologic diagnosis of urothelial tumors
- Correlation of urine cytology and biopsy findings (diagnostic accuracy)
- Other types of carcinoma
- Other malignant tumors
- Major diagnostic pitfalls
- Special aspects of anatomic sites other than the urinary bladder
- Secondary tumors
- Ancillary studies
- The problem of hematuria
CHAPTER 8 - Non-neoplastic diseases of the prostate
- Embryology and fetal–prepubertal history
- Anatomy and histology of the prostate
- Immunohistochemistry
- Prostate sampling techniques
- Prostatic inflammation
- Pathologic changes following needle biopsy
- Non-neoplastic metaplasia
- Hyperplasia and nodular hyperplasia
- Benign non-neoplastic conditions
- Treatment-associated changes
CHAPTER 9 - Neoplasms of the prostate
- Epithelial neoplasms
- Soft tissue neoplasms
- Other neoplasms and tumor-like proliferations
- Other rare tumors and tumor-like conditions
CHAPTER 10 - Seminal vesicles
- Embryology and anatomy
- Congenital and acquired malformations
- Non-neoplastic abnormalities
- Neoplasms
CHAPTER 11 - Urethra
- Embryologic development and normal anatomy
- Congenital anomalies
- Non-neoplastic diseases
- Neoplastic diseases
CHAPTER 12 - Non-neoplastic diseases of the testis
- Embryology and anatomy of the testis
- Congenital anomalies of the testis
- Infertility
- Inflammation and infection
- Other testicular and epididymal lesions
- Other testicular diseases
CHAPTER 13 - Neoplasms of the testis
- Staging
- Patterns of metastasis
- Gross examination
- Germ cell tumors
- Sex cord–stromal tumors
- Mixed germ cell and sex cord–stromal tumors
- Ovarian-type epithelial tumors
- Neoplasms and tumor-like lesions of the rete testis
- Neoplasms of lymphoid and hematopoietic cells
- Miscellaneous lesions
- Diagnostic approach to testicular tumors
CHAPTER 14 - Spermatic cord and testicular adnexae
- Embryology and normal anatomy
- Congenital anomalies
- Non-neoplastic diseases of the spermatic cord and testicular adnexae
- Neoplasms
CHAPTER 15 - Penis and scrotum
PENIS
- Normal anatomy and histology
- Congenital abnormalities
- Non-neoplastic diseases
- Tumor-like conditions
- Neoplastic diseases
SCROTUM
- Normal anatomy and histology
- Non-neoplastic diseases
- Neoplastic diseases
CHAPTER 16 - The adrenal glands
- Embryology and normal gross anatomy
- Microscopic anatomy
- Congenital abnormalities
- Non-neoplastic diseases
- Adrenal neoplasms
- Neuroblastic tumors: neuroblastoma, ganglioneuroblastoma, and ganglioneuroma
- Other adrenal tumors
- Tumors metastatic to the adrenal glands
About the Authors
- David G. Bostwick, MD, MBA, Chief Medical Officer, Bostwick Laboratories, Glen Allen, VA, USA.
- Liang Cheng, MD, Professor of Pathology and Urology, Chief of Genitourinary Pathology Division; Director of Molecular Pathology Laboratory, Department of Pathology and Laboratory Medicine and Clarian Pathology Laboratory, Indiana University School of Medicine, Indianapolis, IN, USA.
Product Details
- Hardcover: 1024 pages
- Publisher: Mosby; 2 edition (June 26, 2008)
- Language: English
- ISBN-10: 0323019706
- ISBN-13: 978-0323019705
- Product Dimensions: 11 x 8.9 x 1.9 inches
List Price: $311.00