In the fourth edition of Comprehensive Clinical Nephrology, we continue to offer a text for fellows, practicing nephrologists, and internists that covers all aspects of the clinical work of the nephrologist, including fluid and electrolytes, hypertension, diabetes, dialysis, and transplantation. We recognize that this single volume does not compete with multivolume, highly referenced texts, and it remains our goal to provide “comprehensive” coverage of clinical nephrology yet also ensure that inquiring nephrologists can find the scientific issues and pathophysiology that underlie their clinical work.
For this edition all chapters have been extensively revised and updated in response to the advice and comments that we have received from many readers and colleagues. New features of the fourth edition include a chapter on inherited causes of nephrotic syndrome, an extended section on diabetic nephropathy, a revised section on infectious diseases and the kidney, a revised and extended section on acute kidney injury, a chapter on herbal and over-the-counter medicines and the kidney, and an extended section on medical management of the kidney transplant recipient.
By popular demand we continue to offer readers access to the images from the book that we are pleased to see used in lectures and seminars in many parts of the world.
This is the first edition that features access to a companion Expert Consult website, with fully searchable text, a downloadable image library, and links to PubMed.
- Authors -
Book Features
- Make efficient, informed decisions with just the right amount of basic science and practical clinical guidance for every disorder.
- Diagnose effectively and treat confidently thanks to more than 1100 illustrations, abundant algorithms, and tables that highlight key topics and detail pathogenesis for a full range of kidney conditions and clinical management.
Website Features
- Consult the book from any computer at home, in your office, or at any practice location.
- Instantly locate the answers to your clinical questions via a simple search query.
- Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
- Images: Browse a Library of all book images. Easily select, organize, and download your images into a presentation.
New in this Edition
- Access the fully searchable text online at www.expertconsult.com, along with a downloadable image gallery.
- Get coverage of the latest developments in the field with 18 new chapters on the Management of the Diabetic Patient with Chronic Kidney Disease, Treatment of Hypertensive Emergencies, Principles of Drug Dosing and Prescribing of Chronic Kidney Disease, Herbal and Over-the-Counter Medicines and the Kidney, Neurologic Complications of the Kidney, and more.
- Tap into the experience and expertise of the world's leading authorities in the field of nephrology.
Section I - Essential Renal Anatomy and Physiology
- CHAPTER 1 - Renal Anatomy
- CHAPTER 2 - Renal Physiology
Section II - Investigation of Renal Disease
- CHAPTER 3 - Assessment of Renal Function
- CHAPTER 4 - Urinalysis
- CHAPTER 5 - Imaging
- CHAPTER 6 - Renal Biopsy
Section III - Fluid and Electrolyte Disorders
- CHAPTER 7 - Disorders of Extracellular Volume
- CHAPTER 8 - Disorders of Water Metabolism
- CHAPTER 9 - Disorders of Potassium Metabolism
- CHAPTER 10 - Disorders of Calcium, Phosphate, and Magnesium Metabolism
- CHAPTER 11 - Normal Acid-Base Balance
- CHAPTER 12 - Metabolic Acidosis
- CHAPTER 13 - Metabolic Alkalosis
- CHAPTER 14 - Respiratory Acidosis, Respiratory Alkalosis, and Mixed Disorders
Section IV - Glomerular Disease
- CHAPTER 15 - Introduction to Glomerular Disease: Clinical Presentations
- CHAPTER 16 - Introduction to Glomerular Disease: Histologic Classification and Pathogenesis
- CHAPTER 17 - Minimal Change Nephrotic Syndrome
- CHAPTER 18 - Primary and Secondary (Non-Genetic) Causes of Focal and Segmental Glomerulosclerosis
- CHAPTER 19 - Inherited Causes of Nephrotic Syndrome
- CHAPTER 20 - Membranous Nephropathy
- CHAPTER 21 - Membranoproliferative Glomerulonephritis, Dense Deposit Disease, and Cryoglobulinemic Glomerulonephritis
- CHAPTER 22 - IgA Nephropathy and Henoch-Schonlein Nephritis
- CHAPTER 23 - Antiglomerular Basement Membrane Disease and Goodpasture's Disease
- CHAPTER 24 - Renal and Systemic Vasculitis
- CHAPTER 25 - Lupus Nephritis
- CHAPTER 26 - Renal Amyloidosis and Glomerular Diseases with Monoclonal Immunoglobulin Deposition
- CHAPTER 27 - Other Glomerular Disorders and Antiphospholipid Syndrome
- CHAPTER 28 - Thrombotic Microangiopathies, Including Hemolytic Uremic Syndrome
Section V - Diabetic Nephropathy
- CHAPTER 29 - Pathogenesis, Clinical Manifestations, and Natural History of Diabetic Nephropathy
- CHAPTER 30 - Prevention and Treatment of Diabetic Nephropathy
- CHAPTER 31 - Management of the Diabetic Patient with Chronic Kidney Disease
Section VI - Hypertension
- CHAPTER 32 - Normal Blood Pressure Control and the Evaluation of Hypertension
- CHAPTER 33 - Primary Hypertension
- CHAPTER 34 - Nonpharmacologic Prevention and Treatment of Hypertension
- CHAPTER 35 - Pharmacologic Treatment of Hypertension
- CHAPTER 36 - Evaluation and Treatment of Hypertensive Urgencies and Emergencies
- CHAPTER 37 - Renovascular Hypertension and Ischemic Renal Disease
- CHAPTER 38 - Endocrine Causes of Hypertension—Aldosterone
- CHAPTER 39 - Endocrine Causes of Hypertension
- CHAPTER 40 - Neurogenic Hypertension, Including Hypertension Associated with Stroke or Spinal Cord Injury
Section VII - Pregnancy and Renal Disease
- CHAPTER 41 - Renal Physiology in Normal Pregnancy
- CHAPTER 42 - Renal Complications in Normal Pregnancy
- CHAPTER 43 - Pregnancy with Preexisting Kidney Disease
Section VIII - Hereditary and Congenital Diseases of the Kidney
- CHAPTER 44 - Autosomal Dominant Polycystic Kidney Disease
- CHAPTER 45 - Other Cystic Kidney Diseases
- CHAPTER 46 - Alport's and Other Familial Glomerular Syndromes
- CHAPTER 47 - Inherited Disorders of Sodium and Water Handling
- CHAPTER 48 - Fanconi Syndrome and Other Proximal Tubule Disorders
- CHAPTER 49 - Sickle Cell Disease
- CHAPTER 50 - Congenital Anomalies of the Kidney and Urinary Tract
Section IX - Infectious Diseases and the Kidney
- CHAPTER 51 - Urinary Tract Infections in Adults
- CHAPTER 52 - Tuberculosis of the Urinary Tract
- CHAPTER 53 - Fungal Infections of the Urinary Tract
- CHAPTER 54 - The Kidney in Schistosomiasis
- CHAPTER 55 - Glomerular Diseases Associated with Infection
- CHAPTER 56 - Human Immunodeficiency Virus Infection and the Kidney
Section X - Urologic Disorders
- CHAPTER 57 - Nephrolithiasis and Nephrocalcinosis
- CHAPTER 58 - Urinary Tract Obstruction
- CHAPTER 59 - Urologic Issues for the Nephrologist
Section XI - Tubulointerstitial and Vascular Diseases
- CHAPTER 60 - Acute Interstitial Nephritis
- CHAPTER 61 - Primary Vesicoureteral Reflux and Reflux Nephropathy
- CHAPTER 62 - Chronic Interstitial Nephritis
- CHAPTER 63 - Myeloma and the Kidney
- CHAPTER 64 - Thromboembolic Renovascular Disease
Section XII - Geriatric Nephrology
- CHAPTER 65 - Geriatric Nephrology
Section XIII - Acute Kidney Injury
- CHAPTER 66 - Pathophysiology and Etiology of Acute Kidney Injury
- CHAPTER 67 - Acute Kidney Injury in the Tropics
- CHAPTER 68 - Diagnosis and Clinical Evaluation of Acute Kidney Injury
- CHAPTER 69 - Prevention and Nondialytic Management of Acute Kidney Injury
- CHAPTER 70 - Dialytic Management of Acute Kidney Injury and Intensive Care Unit Nephrology
- CHAPTER 71 - Ultrafiltration Therapy for Refractory Heart Failure
- CHAPTER 72 - Hepatorenal Syndrome
Section XIV - Drug Therapy in Kidney Disease
- CHAPTER 73 - Principles of Drug Therapy, Dosing, and Prescribing in Chronic Kidney Disease and Renal Replacement Therapy
- CHAPTER 74 - Herbal and Over-the-Counter Medicines and the Kidney
Section XV - Chronic Kidney Disease and the Uremic Syndrome
- CHAPTER 75 - Epidemiology and Pathophysiology of Chronic Kidney Disease
- CHAPTER 76 - Retarding Progression of Kidney Disease
- CHAPTER 77 - Clinical Evaluation and Management of Chronic Kidney Disease
- CHAPTER 78 - Cardiovascular Disease in Chronic Kidney Disease
- CHAPTER 79 - Anemia in Chronic Kidney Disease
- CHAPTER 80 - Other Blood and Immune Disorders in Chronic Kidney Disease
- CHAPTER 81 - Bone and Mineral Metabolism in Chronic Kidney Disease
- CHAPTER 82 - Neurologic Complications of Chronic Kidney Disease
- CHAPTER 83 - Gastroenterology and Nutrition in Chronic Kidney Disease
- CHAPTER 84 - Dermatologic Manifestations of Chronic Kidney Disease
- CHAPTER 85 - Acquired Cystic Kidney Disease and Malignant Neoplasms
Section XVI - Dialytic Therapies
- CHAPTER 86 - Approach to Renal Replacement Therapy
- CHAPTER 87 - Vascular Access for Dialytic Therapies
- CHAPTER 88 - Diagnostic and Interventional Nephrology
- CHAPTER 89 - Hemodialysis: Principles and Techniques
- CHAPTER 90 - Hemodialysis: Outcomes and Adequacy
- CHAPTER 91 - Acute Complications During Hemodialysis
- CHAPTER 92 - Peritoneal Dialysis: Principles, Techniques, and Adequacy
- CHAPTER 93 - Complications of Peritoneal Dialysis
- CHAPTER 94 - Dialytic Therapies for Drug Overdose and Poisoning
- CHAPTER 95 - Plasma Exchange
Section XVII - Transplantation
- CHAPTER 96 - Immunologic Principles in Kidney Transplantation
- CHAPTER 97 - Immunosuppressive Medications in Kidney Transplantation
- CHAPTER 98 - Evaluation and Preoperative Management of Kidney Transplant Recipient and Donor
- CHAPTER 99 - Kidney Transplantation Surgery
- CHAPTER 100 - Prophylaxis and Treatment of Kidney Transplant Rejection
- CHAPTER 101 - Medical Management of the Kidney Transplant Recipient: Infections and Malignant Neoplasms
- CHAPTER 102 - Medical Management of the Kidney Transplant Recipient: Cardiovascular Disease and Other Issues
- CHAPTER 103 - Chronic Allograft Injury
- CHAPTER 104 - Recurrent Disease in Kidney Transplantation
- CHAPTER 105 - Outcomes of Renal Transplantation
- CHAPTER 106 - Pancreas and Islet Transplantation
- CHAPTER 107 - Kidney Disease in Liver, Cardiac, Lung, and Hematopoietic Cell Transplantation
About the Authors
- Jürgen Floege, MD, Medizinische Klinik II, RWTH University of Aachen, Aachen, Germany.
- Richard J. Johnson, MD, Professor of Medicine, Division Chief, Temple Hoyne Buell and NKF of Colorado Endowed Chair of Medicine, University of Colorado, Denver, Aurora, Colorado.
- John Feehally, DM, FRCP, Professor of Renal Medicine, The John Walls Renal Unit, Leicester General Hospital, Leicester, United Kingdom.
Product Details
- Hardcover: 1312 pages
- Publisher: Mosby; 4 edition (November 8, 2010)
- Language: English
- ISBN-10: 0323058760
- ISBN-13: 978-0323058766
- Product Dimensions: 11.1 x 8.8 x 2 inches
List Price: $219.00