It has been 5 years since the publication of the second edition of Cytology: Diagnostic Principles and Clinical Correlates. Since then, cytology has continued to grow and evolve as a subspecialty devoted to the diagnosis of cellular tissue obtained by minimally invasive methods (scraping, brushing, aspiration, etc.), and thus the need for this updated edition. But we have retained many of the qualities of the prior editions. As did the first two, this edition aims to be concise yet comprehensive. We have emphasized brevity and clarity. The text is grounded firmly in an understanding of surgical pathology and current diagnostic terminology. Where relevant, we have illustrated the value of established ancillary studies (e.g., flow cytometry and immunohistochemistry) as well as evolving techniques such as cytogenetics, which can be helpful in the diagnosis of certain lymphomas, soft tissue tumors, renal neoplasms, and mesothelioma.
Although the book is multi-authored, the chapters follow a similar format: indications, sample collection and preparation methods, recommended terminology for reporting results, accuracy (including common pitfalls that lead to false-negative and false-positive diagnoses), a description of normal elements, and finally, a how-to guide for the diagnosis of benign and malignant lesions, with an emphasis on differential diagnosis. We have retained the bulleted “capsule summaries,” particularly for summarizing cytomorphologic features and differential diagnoses. We have continued to emphasize clinical correlation (hence the title). For example, Chapter 1 includes the recently revised algorithms of the American Society for Colposcopy and Cervical Pathology for managing women with abnormal cervical cytologic diagnoses. Good cytologists are those who understand the clinical implications of their interpretations.
Once again, we hope we have succeeded in conveying the beauty, strength, and challenge of cytology. With this book we have tried to take some of the mystery out of cytology. But mysteries remain; their solutions still obscure. If this text inspires the reader to explore and even solve some of them, we will consider ourselves doubly rewarded.
Key Features
- Offers comprehensive coverage of everyday diagnostic work in a concise format for a practical benchside manual.
- Covers every type of cytology---gynecology, non-gynecology, and FNA.
- Presents an in-depth differential diagnosis discussion for all major entities.
- Examines the role of special techniques such as immunohistochemistry, flow cytometry, and molecular biology in resolving difficulties in interpretation and diagnosis.
- Provides an in-depth analysis of common diagnostic pitfalls to assist with daily signing out and reporting.
- Features coverage of patient management in discussions of pertinent clinical features.
- Uses capsule summaries featuring easy-to-read bulleted text that provide a quick review of key differential diagnoses, diagnostic pitfalls, cytomorphologic features, and tissue acquisition protocols for specific entities.
- Includes over 700 full-color illustrations that provide you with a real-life perspective of a full range of cytologic findings.
Website Features
- Consult the book from any computer at home, in your office, or at any practice location.
- Instantly locate the answers to your clinical questions via a simple search query.
- Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
- Images: Browse a Library of all book images. Easily select, organize, and download your images into a presentation.
Contents
Chapter 1 - Cervical and Vaginal Cytology
- The History Of The Pap Test
- Sampling And Preparation Methods
- Automated Screening
- Accuracy And Reproducibility
- Diagnostic Terminology And Reporting Systems
- The Bethesda System
- The Normal Pap
- Organisms And Infections
- Benign And Reactive Changes
- Vaginal Specimens In “des Daughters”
- Squamous Abnormalities
- Glandular Abnormalities
- Other Malignant Neoplasms
- Endometrial Cells In Women Older Than 40 Years Of Age
Chapter 2 - Respiratory Tract
- Normal Anatomy, Histology, And Cytology Of The Respiratory Tract
- Sampling Techniques, Preparation Methods, Reporting Terminology, And Accuracy
- Benign Cellular Change
- Noncellular Elements And Specimen Contaminants
- Infections
- Non-Neoplastic, Noninfectious Pulmonary Diseases
- Benign Neoplasms Of The Lung
- Preneoplastic Changes Of The Respiratory Epithelium
- Lung Cancer
- Uncommon Pulmonary Tumors
- Metastatic Cancers To The Lung
Chapter 3 - Urine And Bladder Washings
- Specimen Collection
- Processing
- Reporting Terminology And Adequacy Criteria
- Accuracy
- Normal Elements
- Benign Lesions
- Urothelial Neoplasms
- Other Malignant Lesions
- Diagnosing Difficult Or Borderline Specimens: Common Patterns
- Ancillary Techniques
- Summary
Chapter 4 - Pleural, Pericardial, And Peritoneal Fluids
- Specimen Collection, Preparation, And Reporting Terminology
- Accuracy
- Benign Elements
- Non-Neoplastic Conditions
- Malignant Effusions
Chapter 5 - Peritoneal Washings
- Specimen Collection, Preparation, And Reporting Terminology
- Accuracy
- The Normal Peritoneal Washing
- Benign Conditions
- Malignant Tumors
- Monitoring Response To Treatment (“second-Look Procedures”)
Chapter 6 - Cerebrospinal Fluid
- Anatomy And Physiology
- Obtaining And Preparing The Specimen
- Reporting Terminology
- Accuracy
- Normal Elements
- Abnormal Inflammatory Cells
- Non-Neoplastic Disorders
- Neoplasms
Chapter 7 - Gastrointestinal Tract
- Clinical Indications
- Sample Collection And Processing
- Accuracy
- Review Of Morphologic Findings
- Esophagus
- Stomach
- Duodenum
- Colon
- The Anal Pap Test
Chapter 8 - Breast
- Specimen Types
- Reporting Terminology
- Evaluation Of The Specimen
- The Normal Breast
- Benign Conditions
- Papillary Neoplasms
- Phyllodes Tumor
- Breast Cancer
- Uncommon Breast Tumors
- Metastatic Tumors
Chapter 9 - Thyroid
- Aspiration Technique And Slide Preparation
- Terminology For Reporting Results
- Accuracy
- Evaluation Of The Specimen
- Benign Conditions
- Atypical Cells Of Undetermined Significance
- Suspicious For A Follicular Neoplasm
- Suspicious For A Hurthle Cell Neoplasm
- Malignant Conditions
- Parathyroid Tumors
Chapter 10 - Salivary Gland
- Rationale, Indications, And Technical Considerations
- Diagnostic Overview
- The Normal Aspirate
- Non-Neoplastic Conditions
- Benign Neoplasms
- Carcinomas Of Salivary Gland Origin
- Rare Malignant Neoplasms
- Other Malignancies
- Miscellaneous
Chapter 11 - Lymph Nodes
- Technical Aspects
- Reporting Terminology And Accuracy
- Ancillary Studies
- Non-Neoplastic Lesions
- Neoplasms
- Nonlymphoid Neoplasms
Chapter 12 - Liver
- Normal Liver
- Infections
- Benign Lesions
- Malignant Tumors
Chapter 13 - Pancreas And Biliary Tree
- Indications
- Sampling Techniques
- Accuracy And Complications
- Sample Preparation And Reporting Technology
- Cyst Fluid Analysis
- Normal Pancreas And Bile Duct
- Pancreatitis And Reactive Changes
- Pseudocyst And Other Non-Neoplastic Cysts
- Ductal Adenocarcinoma
- Variants Of Ductal Adenocarcinoma
- Acinar Cell Carcinoma
- Solid-Pseudopapillary Neoplasm
- Pancreatic Endocrine Neoplasms
- Serous Cystadenoma
- Mucinous Cystic Neoplasm And Intraductal Papillary Mucinous Neoplasm
- Secondary Pancreatic Neoplasms
Chapter 14 - Kidney And Adrenal Gland
The Kidney
- Specimen Collection and Preparation
- Accuracy
- Adequacy
- Normal Elements
- Benign Lesions
- Renal Cell Carcinoma
- Urothelial Carcinoma
- Metastatic Tumors
The Adrenal Gland
- Specimen Collection, Preparation, and Accuracy
- Myelolipoma
- Adrenal Cortical Neoplasms
- Pheochromocytoma
- Metastatic Tumors
Chapter 15 - Ovary
- Obtaining The Specimen
- Preparing The Specimen And Reporting Results
- Accuracy
- Benign Tumor-Like Lesions Of The Ovary
- Benign Surface Epithelial-Stromal Tumors
- Malignant Surface Epithelial-Stromal Tumors
- Germ Cell Tumors
- Sex Cord-Stromal Tumors
- Uncommon Primary Ovarian Tumors
- Metastatic Tumors
Chapter 16 - Soft Tissue
- Specimen Collection And Preparation
- Ancillary Studies
- Reporting Terminology
- Adipocytic Or Lipogenic Neoplasms
- Myxoid Neoplasms
- Spindle Cell Neoplasms
- Fibrohistiocytic Neoplasms
- Round Cell Neoplasms
- Epithelioid Neoplasms
- Pleomorphic Neoplasms
- Non-Neoplastic Soft Tissue Lesions
Chapter 17 - Laboratory Management
- Agencies And Organizations
- Regulations
- Laboratory Personnel
- Policy And Procedure Manuals
- Workflow
- Billing
- Quality Control And Quality Assurance
- Proficiency Testing
- Performance Evaluation
- Safety
About the Authors
- Edmund S. Cibas, MD, Associate Professor, Department of Pathology, Harvard Medical School Director, Division of Cytopathology, Brigham and Women's Hospital, Boston, Massachusetts.
- Barbara S. Ducatman, MD, Professor and Chair, Department of Pathology, Associate Dean for Faculty Services Director, West Virginia University National Center of Excellence in Women's Health, West Virginia University School of Medicine, Morgantown, West Virginia.
Product Details
- Hardcover: 552 pages
- Publisher: Saunders; 3 edition (2010)
- Language: English
- ISBN-10: 1416053298
- ISBN-13: 978-1416053293
- Product Dimensions: 11 x 8.8 x 1 inches
List Price: $199.00