Gough: HbA1c in Diabetes: Case studies using IFCC units






The measurement of HbA1c is a key tool in the treatment of diabetes mellitus. For health care professionals involved in the management of diabetes in the UK there is an additional complication, between 2009 and 2011, with a change of HbA1c units. The old DCCT percentage is giving way to the internationally recognised IFCC units of mmol/mol in 2011.
To further the understanding of HbA1c measurements, the editors have summarised the important issues and then appended a number of case studies involving a wide range of patients from children to the elderly, showing the measurements in both the ‘old’ and ‘new’ units. These cover a wide range of diabetes-related conditions and describe the treatment plans and follow-up. This book will be a useful resource for all those involved in diabetes care as they come to terms with IFCC reporting.

Contents
Introduction 1
Case studies
1: Diagnosis and early management of type 1 diabetes in a young child 29
2: Management of an elderly patient, housebound and living alone 30
3: Gestational diabetes 31
4: Weight loss and improved glycaemic control 32
5: Type 2 diabetes in a child 33
6: Weight reduction 34
7: Improved glycaemic control 35
8: Risk of hypoglycaemia in a patient in a unit for the elderly mentally ill in a nursing home 36
9: Structured education for type 1 diabetes 37
10: Woman with family history of raised cholesterol and diabetes 38
11: Type 1 diabetes in a child 39
12: Poor glucose control with microvascular complications 40
13: Renal failure and cardiovascular disease in an Asian patient 41
14: Type 1 diabetes in a teenage girl concerned about weight 42
15: Glycaemic control through patient empowerment 43
16: Diagnosis and early management of type 2 diabetes in patient with acute coronary syndrome 44
17: Incretin or insulin? 45
18: Type 2 diabetes and pregnancy 46
19: Deterioration of pre-existing diabetes in a patient on low dose quetiapine 47
20: Low HbA1c and risk of hypoglycaemia 48
21: Rapid changes in glycaemic control and retinopathy 49
22: Type 1 diabetes in a young man moving from paediatric to young adult services 50
23: Monitoring glycaemic control: HbA1c or fructosamine 51
24: Prepregnancy and pregnancy in type 1 diabetes 52
25: Maturity onset diabetes of the young, subtype HNF1A (HNF1A-MODY) 53
26: ‘Overtreating’ type 2 diabetes 54
27: Diabetes and an elevated triglyceride concentration 55
28: Multiple therapies leading to bariatric surgery 56
29: Optic neuropathy 57
30: Uncertainty around the estimate of average plasma glucose from HbA1c 58
31: Antipsychotics 59
32: Abnormal liver function in a patient with type 2 diabetes 60
33: Fructosamine in diabetic nephropathy 61
34: Recurrent hypoglycaemia caused by secondary adrenal insuffi ciency 62
35: A patient with diabetes taking niacin 63
36: Tight glycaemic control leading to nocturnal hypoglycaemia 64
37: Diabetes and iron-defi ciency anaemia 65
38: Deterioration in vision after commencing insulin treatment: the early worsening phenomenon 66
39: Type 1 diabetes – worsening glycaemic control on introduction of a pump? 67
40: Monitoring glycaemic control in a patient with sickle cell trait 68
41: Balancing fear of hypoglycaemia with optimal control in pregnancy 69
42: Asian patient with high-risk feet and suboptimal glycaemic control 70
43: Type 2 diabetes and polycystic ovarian syndrome 71
44: Impact of variant haemoglobin AC on HbA1c determination 72
45: Diabetic nephropathy 73
Colour plates related to case studies 29 and 38
Thermometer relating HbA1c to the complications of type 2 diabetes
Conversion table for HbA1c from IFCC to DCCT-aligned units

Book Details

  • Paperback: 88 pages
  • Publisher: Wiley-Blackwell; 1 edition (April 6, 2010)
  • Language: English
  • ISBN-10: 1444334441
  • ISBN-13: 978-1444334449
  • Product Dimensions: 8.8 x 5.8 x 0.2 inches
List List Price: $38.95
 

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