Physiologic Factors that Influence the Oral Absorption of Medications in Neonate, Infant & Child






PARAMETER NEONATE INFANT CHILD
Gastric acid secretion Reduced Normal Normal
Gastric emptying time Decreased Increased Increased
Intestinal motility Reduced Normal Normal
Biliary function Reduced Normal Normal
Microbial flora Acquiring Adult pattern Adult pattern

Reference:
Nelson Textbook of Pediatrics 18th Edition
 

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