Category A
Consists of one or more of the conditions listed below in an adolescent or adult (>13 years) with documented HIV infection. Conditions listed in categories B and C must not have occurred.
- Asymptomatic HIV infection.
- Persistent generalized lymphadenopathy.
- Acute (primary) HIV infection with accompanying illness or history of acute HIV infection.
Category B
Consists of symptomatic conditions in an HIV-infected adolescent or adult that are not included among conditions listed in clinical category C and that meet at least one of the following criteria:
- The conditions are attributed to HIV infection or are indicative of a defect in cell-mediated immunity; or
- The conditions are considered by physicians to have a clinical course or to require management that is complicated by HIV infection.
Examples include, but are not limited to, the following:
- Bacillary angiomatosis.
- Candidiasis, oropharyngeal (thrush).
- Candidiasis, vulvovaginal; persistent, frequent, or poorly responsive to therapy.
- Cervical dysplasia (moderate or severe)/cervical carcinoma in situ.
- Constitutional symptoms, such as fever (38.5°C) or diarrhea lasting >1 month.
- Hairy leukoplakia, oral.
- Herpes zoster (shingles), involving at least two distinct episodes or more than one dermatome.
- Idiopathic thrombocytopenic purpura.
- Listeriosis.
- Pelvic inflammatory disease, particularly if complicated by tuboovarian abscess.
- Peripheral neuropathy.
Category C
Conditions listed in the AIDS surveillance case definition.
- Candidiasis of bronchi, trachea, or lungs.
- Candidiasis, esophageal.
- Cervical cancer, invasivea.
- Coccidioidomycosis, disseminated or extrapulmonary.
- Cryptococcosis, extrapulmonary.
- Cryptosporidiosis, chronic intestinal (>1 month's duration).
- Cytomegalovirus disease (other than liver, spleen, or nodes).
- Cytomegalovirus retinitis (with loss of vision).
- Encephalopathy, HIV-related.
- Herpes simplex: chronic ulcer(s) (>1 month's duration); or bronchitis, pneumonia, or esophagitis.
- Histoplasmosis, disseminated or extrapulmonary.
- Isosporiasis, chronic intestinal (>1 month's duration).
- Kaposi's sarcoma.
- Lymphoma, Burkitt's (or equivalent term).
- Lymphoma, primary, of brain.
- Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary.
- Mycobacterium tuberculosis, any site (pulmonarya or extrapulmonary).
- Mycobacterium, other species or unidentified species, disseminated or extrapulmonary.
- Pneumocystis jiroveci pneumonia.
- Pneumonia, recurrenta.
- Progressive multifocal leukoencephalopathy.
- Salmonella septicemia, recurrent.
- Toxoplasmosis of brain.
- Wasting syndrome due to HIV.