Chronic Rhinosinusitis: Pathogenesis and Medical Management (Clinical Allergy and Immunology Series)






It was not too long ago when the treatment paradigm for chronic rhinosinusitis was a failure to respond to several courses of antibiotics, followed by surgery, which usually consisted of nasal-antral windows and/or a Caldwell-Luck procedure. Both procedures were developed many years ago and have been almost uniformly abandoned within the last 10 to 15 years. If physicians today are frustrated with the difficulty in managing chronic rhinosinusitis, they need only remember that the standards described above, although they seem to be ancient relative to our options today, were followed until very recently. 

Yet even today the symptoms of chronic rhinosinusitis are not always well defined, it is still difficult to properly examine and assess the sinus cavities, and the treatments employed are often less than spectacular. Thus, it takes a specialist physician to diagnose and treat this chronic disorder. Rhinosinusitis is an exceptionally prevalent disease, and its frequency appears to be increasing. Not only is the disease disabling in its own right, it often complicates the ability to smell, taste, and hear, causes chronic cough and headache, and is a co-morbid condition for asthma. New understanding of rhinosinusitis has improved our knowledge of its pathophysiology, classification, symptoms, and signs, and has led to more effective medical and surgical treatments. 

For these reasons, it is indeed a pleasure to welcome Chronic Rhinosinusitis as the 20th volume in the Clinical Allergy and Immunology Series. This workrepresents the combined talents of two outstanding leaders—one in the field of allergy/immunology and one in the field of otolaryngology—and their guidance has led to a wonderfully readable and important book. Thanks to Drs. Daniel Hamilos and Fuad Baroody for their creativity and hard work in bringing this fine book to publication. The authors are a “Who’s Who” of leaders in this field, and the chapters included allow the reader to better understand the pathogenesis, diagnosis, and new and novel treatments for chronic rhinosinusitis. 

The series of books that this volume joins is designed to translate basic science into clinical medicine. Chronic Rhinosinusitis continues this tradition. It should be of interest to both scientists and clinicians, and should be required reading for all physicians interested in rhinosinusitis, including those in family medicine, internal medicine, pediatrics, allergy, and otolaryngology.

Contents 
1. Chronic Rhinosinusitis Patterns of Illness
2. Impact of Chronic Rhinosinusitis on Quality of Life and Health Care Expenditure
3. Environmental and Allergic Factors in Chronic Rhinosinusitis
4. Innate and Acquired Immunity and Epithelial Cell Function in Chronic Rhinosinusitis
5. Role of Inflammatory T Cells and Eosinophils in Chronic Rhinosinusitis
6. Role of Mast Cells and Basophils in Chronic Rhinosinusitis
7. Mucociliary Transport in Chronic Rhinosinusitis
8. Chronic Rhinosinusitis with Glandular Hypertrophy
9. Bacterial Infection and Antibiotic Treatment in Chronic Rhinosinusitis
10. Staphylococcus aureus Enterotoxins as Immune Stimulants in Chronic Rhinosinusitis
11. The Role of Ubiquitous Airborne Fungi in Chronic Rhinosinusitis
12. Imaging of Paranasal Sinuses and Rhinosinusitis
13. The Role of Nasal Endoscopy in the Diagnosis and Medical Management of Chronic Rhinosinusitis
14. Role of Steroids in the Treatment of Rhinosinusitis with and Without Polyposis
15. Adjuvant Therapies in the Treatment of Acute and Chronic Rhinosinusitis
16. Allergic Fungal Sinusitis
17. Medical Management of Rhinosinusitis Comorbidities—Asthma, Aspirin Sensitivity, Gastroesophageal Reflux, Immune Deficiencies
18. Chronic Rhinosinusitis: Contrasts Between Children and Adult Patients
19. Approach to the Evaluation and Medical Management of Chronic Rhinosinusitis
20. Interfacing Medical and Surgical Management for Chronic Rhinosinusitis with and Without Nasal Polyps
Index 

Book Details

  • Hardcover: 368 pages
  • Publisher: Informa Healthcare; 1 edition
  • Language: English
  • ISBN-10: 0849340527
  • ISBN-13: 978-0849340529
  • Product Dimensions: 9.1 x 6.2 x 0.9 inches
List Price: $199.95
 

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