Pediatric Allergy: Principles and Practice is aimed at updating the reader on the pathophysiology of allergic responses and the atopic triad (asthma, allergic rhinitis, and atopic dermatitis), the mechanisms underlying specific allergic and immunologic diseases, and their socioeconomic impact and new treatment approaches that take advantage of emerging concepts of the pathobiology of these diseases. An outstanding group of authors who are acknowledged leaders in their fields has been assembled because of their personal knowledge, expertise, and involvement with their subject matter in children. Every effort has been made to achieve prompt publication of this book, thus ensuring that the content of each chapter is 'state of the art.'
Section A presents general concepts critical to an understanding of the impact and causes of allergic diseases. These include reviews of the epidemiology and natural history of allergic disease, genetics of allergic disease and asthma, biology of inflammatory-effector cells, regulation of IgE synthesis, and the developing immune system and allergy.
Section B reviews an approach to the child with recurrent infection and specific immunodeficiency and autoimmune diseases that pediatricians frequently encounter.
Section C updates the reader on a number of important and emerging immune-directed therapies including immunoglobulin therapy, bone marrow transplantation, immunizations, gene therapy, and stem cell therapy.
Section D examines the diagnosis and treatment of allergic disease. The remainder of the book is devoted to the management and treatment of asthma and a number of specific allergic diseases such as upper airway disease, food allergy, allergic skin and eye diseases, drug allergy, latex allergy, insect hypersensitivity, and anaphylaxis.
In each chapter, the disease is discussed in the context of its differential diagnoses, key concepts, evaluations, environmental triggers, and concepts of emerging and established treatments.
Section A presents general concepts critical to an understanding of the impact and causes of allergic diseases. These include reviews of the epidemiology and natural history of allergic disease, genetics of allergic disease and asthma, biology of inflammatory-effector cells, regulation of IgE synthesis, and the developing immune system and allergy.
Section B reviews an approach to the child with recurrent infection and specific immunodeficiency and autoimmune diseases that pediatricians frequently encounter.
Section C updates the reader on a number of important and emerging immune-directed therapies including immunoglobulin therapy, bone marrow transplantation, immunizations, gene therapy, and stem cell therapy.
Section D examines the diagnosis and treatment of allergic disease. The remainder of the book is devoted to the management and treatment of asthma and a number of specific allergic diseases such as upper airway disease, food allergy, allergic skin and eye diseases, drug allergy, latex allergy, insect hypersensitivity, and anaphylaxis.
In each chapter, the disease is discussed in the context of its differential diagnoses, key concepts, evaluations, environmental triggers, and concepts of emerging and established treatments.
Major advances in this second edition include updates on new genetic advances in allergic diseases, inflammatory conditions and immunodeficiencies, new biomarkers to monitor allergic diseases, recent revisions in asthma guidelines emphasizing a step-care approach to control asthma, appropriate evaluation of drug allergy and a better understanding of drug cross-reactivity to eliminate the difficulty prescribing antibiotics in the pediatric population, the role of new biologics and immunomodulatory therapy in the treatment of inflammatory diseases and emerging evidence that barrier dysfunction can drive allergic disease.
Book Features
- Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians.
- Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches.
- Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases.
New in this edition
- Access the fully searchable contents online at expertconsult.com, where you'll also find a downloadable image bank.
- Apply the newest diagnostic tests available-for asthma, upper respiratory allergy, and more-and know their benefits and contraindications.
- Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases.
- Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals.
- Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease.
- Effectively control asthma and monitor its progression using the new step-by-step approach.
- Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.
Sect. A General Concepts
- 1 Epidemiology of Allergic Diseases
- 2 Natural History of Allergic Diseases and Asthma
- 3 The Genetics of Allergic Disease and Asthma
- 4 Regulation and Biology of Immunoglobulin E
- 5 Inflammatory Effector Cells/Cell Migration
- 6 The Developing Immune System and Allergy
Sect. B Immunologic Diseases
- 7 Approach to the Child with Recurrent Infections
- 8 Antibody Deficiency
- 9 T Cell Immunodeficiencies
- 10 Pediatric Human Immunodeficiency Virus Infection
- 11 Complement Deficiencies
- 12 White Blood Cell Defects
- 13 Rheumatic Diseases of Childhood: Therapeutic Principles
- 14 Autoimmune Diseases
- 15 Autoimmune Lymphoproliferative Syndrome
- 16 Epstein-Barr Virus Infections
Sect. C Immune-Directed Therapies
- 17 Intravenous Immune Serum Globulin Therapy
- 18 Bone Marrow Transplantation
- 19 Immunizations
- 20 Gene Therapy and Allergy
- 21 Stem Cell Therapeutics: An Overview
Sect. D Diagnosis and Treatment of Allergic Disease
- 22 Laboratory (In Vitro) Analyses
- 23 In Vivo Testing for Immunoglobulin E-Mediated Sensitivity
- 24 Outdoor Allergens
- 25 Indoor Allergens
- 26 Environmental Control
- 27 Immunotherapy for Allergic Disease
Sect. E Upper Airway Disease
- 28 Allergic Rhinitis
- 29 Otitis Media
- 30 Sinusitis
- 31 Chronic Cough
Sect. F Asthma
- 32 Immunology of the Asthmatic Response
- 33 Guidelines for Treatment of Asthma
- 34 Functional Assessment of Asthma
- 35 Infections and Asthma
- 36 Special Considerations for Infants and Young Children
- 37 Inner City Asthma
- 38 Asthma in Older Children
- 39 Asthma Education Programs for Children
- 40 Asthma and the Athlete
- 41 Refractory Childhood Asthma: New Insight into the Pathogenesis, Diagnosis, and Management
- 42 Promoting Adherence and Effective Self-Management in Patients with Asthma
- 43 New Directions in Asthma Management
Sect. G Food Allergy
- 44 Mucosal Immunity: An Overview
- 45 Evaluation of Food Allergy
- 46 Approach to Feeding Problems in the Infant and Young Child
- 47 Prevention and Natural History of Food Allergy
- 48 Enterocolitis, Proctocolitis, and Enteropathy
- 49 Eosinophilic Esophagitis, Gastroenteritis, and Proctocolitis
- 50 Food Allergy, Respiratory Disease, and Anaphylaxis
- 51 Atopic Dermatitis and Food Hypersensitivity
- 52 Management of Food Allergy
Sect. H Allergic Skin and Eye Diseases
- 53 Atopic Dermatitis
- 54 Urticaria and Angioedema
- 55 Contact Dermatitis
- 56 Allergic and Immunologic Eye Disease
Sect. I Drug Allergy and Anaphylaxis
- 57 Drug Allergy
- 58 Latex Allergy
- 59 Insect Sting Anaphylaxis
- 60 General Treatment of Anaphylaxis
App. I Clinical Immunology Laboratory Values
App. II Food Allergy
Index
Product Details
- Hardcover: 704 pages
- Publisher: Saunders; 2 edition (October 13, 2010)
- Language: English
- ISBN-10: 1437702716
- ISBN-13: 978-1437702712
- Product Dimensions: 11.1 x 8.9 x 1.3 inches
List Price: $125.00