Hemophilia A and B are lifelong inherited X-linked bleeding disorders, caused by the deficiency of factor VIII (FVIII) or IX (FIX) in plasma. The clinical hallmark of hemophilias is bleeding into the joints and muscles, which can occur spontaneously in the severe forms of the diseases (FVIII/FIX < 1 IU/dl). The joints more frequently involved are the ankles, knees, and elbows, and the recurrence of joint bleeding leads to the formation of ‘target’ joints. The final consequence of repeated hemarthroses is the development of hemophilic arthropathy, characterized by synovial hypertrophy, cartilage destruction, and bone damage with stiffness, pain, and ultimately permanent disability.
Severe hemophilia is a lifelong inherited bleeding disorder characterized by recurrent joint bleeding, which results in chronic, painful, and disabling arthropathy. Since the 1990s, the greater availability of safe and effective clotting factor concentrates has allowed satisfactory results to be achieved in hemophilia care.
Unfortunately, up to 70–80% of hemophiliacs worldwide, particularly in developing countries, still have no access to adequate replacement therapy and consequently frequently develop musculoskeletal complications with severe impairment of their quality of life. Therefore, the role of the orthopedic surgeon becomes crucial in the management of such patients.
This book aims to elucidate peri-operative and operative management of hemophiliac patients. It focuses on surgical techniques in order to give both fundamental and specialized information to those involved with hemophilia treatment worldwide, and to give useful advice to any orthopedic surgeon who is working in this challenging field.
From the Back Cover
Edited by two leading orthopedic surgeons who are specialists in the treatment of hemophilia, Orthopedic Surgery in Patients with Hemophilia shows all the surgical techniques needed for surgical treatment of musculoskeletal complications of hemophilia. A practical guide, designed for use on the ward or in the office, this book draws on the experience of numerous specialists worldwide, from developed and developing countries. As well as orthopedic surgery, it also covers research, hematology, and rehabilitation. Although of primary interest to the orthopedic surgeon, rheumatologist, and physiotherapist, this book will also be relevant to the hematologist responsible for the care of the hemophiliac patient.
Contents
- 1 Professor Henri Horozowski. In Memoriam
Section I Pathogenesis
- 2 Joint Damage as a Result of Hemarthrosis
Section II Peri-operative Management of Hemophiliac Patients
- 3 Conservative or Surgical Treatment? Motion Analysis Can Help Decide
- 4 Orthopedic Surgery in HIV-Positive Hemophiliac Patients
- 5 The Liver and Surgery
- 6 Peri-operative and Post-operative Management of Hemophiliac Patients without Inhibitors
- 7 Peri-operative and Post-operative Management of Hemophiliac Patients with Inhibitors
- 8 Postsurgical Pain
Section III Non-surgical Procedures
- 9 Arthrocentesis
- 10 Intra-articular Hyaluronic Acid Therapy
- 11 Intra-articular Corticosteroid Therapy
- 12 Rifampicin Synoviorthesis of the Ankle Joint
- 13 Radioactive Synoviorthesis of the Knee
Section IV Upper Limb
- 14 Arthroscopic Treatment of Hemophilic Arthropathy of the Shoulder
- 15 Radial Head Excision for Patients with Hemophilic Arthropathy of the Elbow
- 16 Tendon Lengthening in Volkmann´s Ischemic Contractures in Hemophilia
Section V Lower Limb
- 17 Hip Osteotomy in Hemophilia
- 18 Total Hip Arthroplasty in Patients with Hemophilia
- 19 Pitfalls in Total Hip Replacement
- 20 Management of the Hemophilic Knee
- 21 Treatment of Knee Flexion Contractures using Casts and Hinges
- 22 Arthroscopic Evaluation of the Knee
- 23 Lengthening of Hamstring Tendons in Knee Flexion Contractures
- 24 Knee Osteotomy
- 25 Supracondylar Extension Osteotomy for the Treatment of Fixed Knee Flexion Contracture in Hemophiliac Patients
- 26 Primary Total Knee Replacement
- 27 Pitfalls in Primary Total Knee Replacement
- 28 Arthroscopic Treatment of Hemophilic Arthropathy of the Ankle
- 29 Surgical Resection of Osteophyte in the Ankle Joint
- 30 Ankle Arthrodesis
Section VI Bone Defects
- 31 Percutaneous Treatment of Hemophilic Cysts using “Fibrin Glue”
- 32 Intraosseous and Subchondral Cysts
- 33 Surgical Treatment of Hemophilic Pseudotumors
- 34 Percutaneous Treatment of Hemophilic Pseudotumors
Section VII Traumatology
- 35 Treatment of Closed Fractures in Hemophiliac Patients
- 36 Treatment of Exposed Fractures in Hemophiliac Patients
- 37 Orthopedic Surgery in Hemophiliac Patients: a Physiotherapist’s Point of View
- 38 Ten Pieces of Advice for an Orthopedic Surgeon
Subject Index
About the Author
- Horacio Caviglia is Professor of Orthopaedic Surgery at Buenos Aires University, Buenos Aires, Argentina. He is also the Past President of Musculoskeletal Committee of WFH. He published several articles in journals such as Haemophilia and Clinical Orthopedics and Related Research.
- Luigi Piero Solimeno is an Orthopaedic Surgeon and Chief of Hemophilic Arthropathy Treatment Centre "Maria Grazia Gatti Randi" in Milan, Italy. He is the Vice Junior President of Musculoskeletal Committee of WFH. He also published for Haemophilia.
Book Details
- Hardcover: 284 pages
- Publisher: Springer; 1 edition (July 1, 2008)
- Language: English
- ISBN-10: 8847008530
- ISBN-13: 978-8847008533
List Price: $209.00