In the decade since the previous edition of this book was published, the field of human IVF has undergone significant transformation in many diff erent ways. Further scientific knowledge gained from use of sophisticated technology is one of them; management of patients and treatment cycles has also been influenced by commercial pressures as well as legislative issues. The rapid expansion in both numbers of cycles and range of treatments off ered has introduced a need for more rigorous control and discipline in the IVF laboratory routine, and it is especially important that IVF laboratory personnel have a good basic understanding of the science that underpins our attempts to create the potential beginning of a new life.
IVF is practiced in most countries of the world, and the number of babies born is estimated to be in the order of at least 10 million; a vast and comprehensive collection of published literature covers clinical and scientific procedures and protocols, as well as information gained from modern molecular biology techniques. Many books are now available that cover every chapter (and in some cases individual paragraphs) of this edition.
Unlike 10 years ago, a wide range and variety of media, equipment and supplies is available specifically for use in human IVF, each with its own instructions and protocols for use. IVF is successfully carried out with numerous adaptations in individual labs, and specific detailed protocols are no longer appropriate. Our
aim in preparing this third edition was to try to distill large bodies of information relevant to human IVF into a comprehensive background of physiological, biochemical and physical principles that provide the scientific foundation for well-established protocols in current use.
Contents
- 1 Review of cell and molecular biology
- 2 Endocrine control of reproduction: Controlled ovarian hyperstimulation for ART
- 3 Gametes and gametogenesis
- 4 Sperm–oocyte interaction
- 5 First stages of development
- 6 Implantation and early stages of fetal development
- 7 Stem cell biology
- 8 The clinical in-vitro fertilization laboratory
- 9 Quality management in the IVF laboratory
- 10 Sperm and ART
- 11 Oocyte retrieval and embryo culture
- 12 Cryopreservation of gametes and embryos
- 13 Micromanipulation techniques
- 14 Preimplantation genetic diagnosis
- 15 Epigenetics and assisted reproduction
- Index
- The color plates
Product Details
- Paperback: 288 pages
- Publisher: Cambridge University Press; 3 edition (February 14, 2011)
- Language: English
- ISBN-10: 0521730724
- ISBN-13: 978-0521730723
- Product Dimensions: 9.6 x 7.4 x 0.7 inches
List Price: $65.00