Koda-Kimble: Applied Therapeutics: The Clinical Use of Drugs 9th Edition

It has been nearly 35 years since the first edition of Applied Therapeutics: The Clinical Use of Drugs was published. The use of case studies served as a founding principle for this innovative text and remains integral to the current edition. Our authors present patient cases that stimulate the reader to integrate and apply therapeutic principles in the context of specific clinical situations. We also strive to provide students and practitioners with a glimpse into the minds of clinicians who are assessing and solving therapeutic problems so that they too can develop and refine their own problem-solving skills. All chapters in this edition have been revised and updated to reflect our changing knowledge of drugs and the application of this knowledge to the therapy of patients.
Today, it is more critical than ever that health care providers make informed decisions regarding the clinical use of drugs. As our population ages, more people carry the burden of multiple chronic diseases. New knowledge about pathophysiology and drug targets has expanded our approaches to drug therapy and, in many cases, polypharmacy has become the standard of care. This, in turn, increases patient exposure to adverse medication events. Meanwhile, we observe a health care system under considerable stress. Shortages of nurses, pharmacists, physicians, and other health care providers interface with remarkable new technologies, increased costs, and decreased access to care. Ironically, the number of disadvantaged and underserved populations continue to increase at a time of remarkable economic growth. This underscores the importance of finding better approaches to managing escalating costs while enhancing the quality of care provided. Systems and approaches to care that guarantee freedom from medical errors (including medication errors) are urgently needed.
The authors have drawn much information from the literature, current standards, and their clinical experiences to share how one might think about making sound and thoughtful therapeutic decisions. However, it remains the responsibility of every practitioner to evaluate the appropriateness of a particular opinion in the context of the actual clinical situation, keeping in mind any new developments in the field. We strongly urge students and practitioners to consult several appropriate information sources when working with new and unfamiliar drugs.

Brian K. Alldredge

Robin L. Corelli

B. Joseph Guglielmo

Mary Anne Koda-Kimble

Wayne A. Kradjan

Lloyd Yee Young

Bradley R. Williams

Book Features 

• New chapter (Chapter 6) entitled "Pharmacogenomics"
• New chapter (Chapter 103) entitled "Osteoporosis" which was previously covered with other material
• Culturally competent care issues are now incorporated into many chapters
• Coverage of Transplantation now broken into two chapters (35 and 36) in order to adequately cover the topic
• Case studies integrated into each chapter illustrate key concepts and principles of therapeutics and give students practice in developing their own evidence-based therapeutic plans. Students learn the basics of the disease and then learn how to think as clinicians in approaching the drug treatment of the disease.
• All chapters completely updated and revised to incorporate the latest drug treatments and therapeutic practices and guidelines.
• Over 850 tables provide quick access to comparative drug information, pharmacokinetic properties, treatment options, dosing guidelines, risk factors, and disease and diagnosis information.
• Contributors are all leading clinicians with many years of evidence-based care; the case studies reflect their experiences.  

Contents 

01 Assessment of Therapy and Pharmaceutical Care
02 Interpretation of Clinical Laboratory Tests
03 Herbs and Nutritional Supplements
04 Anaphylaxis and Drug Allergies
05 Managing Acute Drug Toxicity
06 Pharmacogenomics
07 End-of-Life Care
08 Nausea and Vomiting
09 Pain and its Management
10 Perioperative Care
11 Acid-Base Disorders
12 Fluid and Electrolyte Disorders
13 Dyslipidemias, Atherosclerosis, and Coronary Heart Disease
14 Essential Hypertension
15 Peripheral Vascular Disorders
16 Thrombosis
17 Ischemic Heart Disease: Anginal Syndromes
18 Myocardial Infarction
19 Heart Failure
20 Cardiac Arrhythmias
21 Hypertensive Emergencies
22 Shock
23 Asthma
24 Chronic Obstructive Pulmonary Disease
25 Acute and Chronic Rhinitis
26 Drug-Induced Pulmonary Disorders
27 Upper Gastrointestinal Disorders
28 Lower Gastrointestinal Disorders
29 Alcoholic Cirrhosis
30 Adverse Effects of Drugs on the Liver
31 Acute Renal Failure
32 Chronic Renal Failure
33 Renal Dialysis
34 Dosing of Drugs in Renal Failure
35 Kidney, Liver, and Pancreas Transplantation
36 Heart and Lung Transplantation
37 Adult Enteral Nutrition
38 Adult Parenteral Nutrition
39 Dermatotherapy and Drug Induced Skin Disorders
40 Acne
41 Psoriasis
42 Photosensitivity and Burns
43 Gout and Hyperuricemia
44 Rheumatic Disororders
45 Connective Tissue Disorders: The Clinical Use of Corticosteroids
46 Contraception
47 Obstetric Drug Therapy
48 Treatment of Menstrual and Menstrual-Related Disorders
49 Climacteric and Postmenopause
50 Thyroid Disorders
51 Diabetes Mellitus
52 Eye Disorders
53 Headache
54 Parkinson's Disease & Other Movement Disorders
55 Seizure Disorders
56 Cerebrovascular Disorders
57 Principles of Infectious Diseases
58 Antimocrobial Prophylaxis for Surgical Procedures
59 Central Nervous System Infections
60 Endocarditis
61 Repiratory Tract Infections
62 Tuberculosis
63 Infectious Diarrhea
64 Intra-Abdominal Infections
65 Urinary Tract Infections
66 Sexually Transmitted Diseases
67 Osteomyelitis and Septic Arthritis
68 Traumatic Skin and Soft Tissue Infections
69 Prevention and Treatment of Infections in Neutropenic Cancer Patients
70 Pharmacotherapy of Human Immunodeficiency Virus Infection
71 Opportunistic Infections in HIV-Infected Patients
72 Fungal Infections
73 Viral Infections
74 Viral Hepatitis
75 Parasitic Infections
76 Tick-Borne Disease
77 Anxiety Disorders
78 Sleep Disorders
79 Schizophrenia
80 Mood Disorders I: Major Depressive Disorders
81 Mood Disorders II: Bipolar Disorders
82 Psychiatric Disorders in Children and Adolescents
83 Eating Disorders
84 Drug Abuse
85 Alcohol Abuse
86 Tobacco Use and Dependence
87 Anemias
88 Drug-induced Blood Disorders
89 Neoplastic Disorders and Their Treatment: General Principles
90 Adverse Effects of Chemotherapy
91 Hematological Malignancies
92 Solid Tumors
93 Hematopoietic Cell Transplantation
94 Pediatric Considerations
95 Neonatal Therapy
96 Pediatric Immunizations
97 Pediatric Infectious Diseases
98 Pediatric Nutrition
99 Cystic Fibrosis
100 Geriatric Drug Use
101 Geriatric Dementias
102 Geriatric Urological Disorders
103 Osteoporosis

Product Details

• Hardcover: 3040 pages
• Publisher: Lippincott Williams & Wilkins; Ninth edition (August 20, 2008)
• Language: English
• ISBN-10: 0781765552
• ISBN-13: 978-0781765558
• Product Dimensions: 10.9 x 8.7 x 3 inches

List Price: $190.95