In the Molecular Pathology Library series, basic science and technology are integrated with the medical perspective and clinical application. Each book in the series is divided according to neoplastic and nonneoplastic diseases for each of the organ systems traditionally associated with medical subspecialties.
Each book in the series is organized to provide:
- (1) a succinct background of the essential terminology, concepts, and technology of molecular biology;
- (2) an overview of the broad application of molecular biology principles to disease; and
- (3) specific application of molecular pathology to the pathogenesis, diagnosis, and treatment of neoplastic and nonneoplastic diseases specific to each organ system.
These broad section topics are divided into succinct chapters, averaging about 15–20 pages each, to cover a very specific disease entity. The chapters are written by established authorities on the specific topic from academic centers around the world. In one book, diverse subjects are included that the reader would have to pursue from multiple sources to have a clear understanding of the molecular pathogenesis, diagnosis, and treatment of specific diseases. Attempting to hunt for the full information from basic concept to specific applications for a disease from the varied sources is time consuming and frustrating. By providing this quick and user-friendly reference, understanding and application of this rapidly growing field are made more accessible to both expert and generalist alike.
As books that bridge the gap between basic science and clinical understanding and practice, the Molecular Pathology Series serves the basic scientist, the clinical researcher, and the practicing physician or other health care provider who require more understanding of the application of basic research to patient care, that is, from “bench to bedside.” This series is unique and an invaluable resource to those who need to know about molecular pathology from a clinical, disease-oriented perspective. These books will be indispensable to physicians and health care providers in multiple disciplines, as already noted, to residents and fellows in these multiple disciplines as well as their teaching institutions, and to researchers who increasingly must justify the clinical implications of their research.
- Chapter 1 Genes, Gene Products, and Transcription Factors
- Chapter 2 Receptors, Signaling Pathways, Cell Cycle, and DNA Damage Repair
- Chapter 3 Cell Adhesion Molecules
- Chapter 4 Apoptosis and Cell Death
- Chapter 5 The Role of Mutation and Epimutation in the Development of Human Disease
- Chapter 6 Bioinformatics and Omics
- Chapter 7 General Approach to Molecular Pathology
- Chapter 8 Applications in Anatomic Pathology
- Chapter 9 Polymerase Chain Reaction and Reverse Transcription-Polymerase Chain Reaction
- Chapter 10 Array Comparative Genomic Hybridization in Pathology
- Chapter 11 Loss of Heterozygosity
- Chapter 12 In Situ Hybridization: Principles and Applications
- Chapter 13 Proteomics
- Chapter 14 Immunohistochemistry of Biomarkers
- Chapter 15 Basic Principles of Flow Cytometry
- Chapter 16 Stem Cells
- Chapter 17 Animal Models of Lung Disease
- Chapter 18 Tissue Culture Models
- Index
Book Details
- Paperback: 224 pages
- Publisher: Springer; 1 edition (June 25, 2009)
- Language: English
- ISBN-10: 0387896252
- ISBN-13: 978-0387896250
- Product Dimensions: 10.9 x 8.2 x 0.5 inches