This interesting volume on advanced perioperative protection during cardiac surgery is an excellent compilation of past, present and future science of this very important and fundamental topic for every cardiac surgeon.
The idea for this book was conceived by Bruno Podesser in 2006, after realizing that there had been no comprehensive summary of myocardial protection during cardiac surgery since a book edited by HM Piper and CJ Preusse in 1993 (Ischemia Reperfusion in Cardiac Surgery).
The Editors, Dr. Chambers and Podesser have assembled an all star cast of excellent clinicians and scientists, experts in the general fields of basic cardiac research, cardioplegia research and clinical outcomes research. After an initial excellent historical chapter the various authors present much of the basic science of myocyte physiology, myocardial protection, subjects that have not been well understood. These basic concepts have been summarized beautifully in this book for clinicians and basic science investigators alike. The next section discusses much of what is currently known about the clinical and physiological effect of cardioplegia on the beating and arrested heart, the optimal protection for the transplanted heart, specific recommendations for right heart protection and a variety of modalities to achieve optimal protection in these situations.
Finally, there are several chapters about the potential future of improved protective cardiac strategies during surgery for an increasing number of patients, particularly the elderly, who will require cardiac surgery over the next decades. The authors have done an excellent job in putting together the best of science and clinical practice of a subject which is critical to successful cardiac surgery and which was put into effect only 30 years ago with the institution of hyperkalemic cardioplegia. Cardioplegia has become a scientific and clinical requirement for excellence in heart surgery.
Therefore, this update in advanced perioperative protection is urgently needed. The results and strategies presented in this book will expand our knowledge on injury and protection of the heart and thereby can improve the outcome of our daily work.
Contents
Part I Introduction
- 1 The Changing Population: The Surgeon’s Challenge
Part II Fundamentals
- 2 Fundamentals of the Past: Cardioplegia: The First Period Revisited
- 3 Sites of Injury: Myocyte
- 4 Sites of Injury: The Endothelium
Part III Special Focus
- 5 Intraoperative Protection of the Myocardium: Effects of Age and Gender
- 6 Protection of the Right Heart
- 7 Protection of the Failing Heart
- 8 Protection During Heart Transplantation
Part IV New Approaches and Technologies
- 9 The Endothelium As Target for Interventions
- 10 Vascular Effects of Cardioplegic Arrest and Cardiopulmonary Bypass
- 11 Oxygen Radical Scavengers
- 12 New Approaches to Cardioplegia: Alternatives to Hyperkalemia
- 13 Myocardial Protection via the Coronary Venous Route
- 14 Donor Heart Preservation by Continuous Perfusion
- 15 Visualization of Cardioplegia Delivery
Author Index
Subject Index
About the Editors
Book Details
- Hardcover: 303 pages
- Publisher: Springer; 1st edition (January 19, 2011)
- Language: English
- ISBN-10: 3211855475
- ISBN-13: 978-3211855478
- Product Dimensions: 9.4 x 6.3 x 0.7 inches
List Price: $209.00