Rosenthal: Medical Biochemistry: Human Metabolism in Health and Disease

Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.
Medical Biochemistry enables readers to master the essentials of human metabolism by explaining how metabolic pathways and reactions are connected to human health and disease. Rather than cover all the reactions that human cells and tissues are capable of executing, this text better enables readers to learn core concepts by emphasizing select examples that illustrate the physiologic and pathophysiologic significance of the major metabolic pathways. Designed for medical, dental, and allied health students and professionals, the text emphasizes clinically relevant information, helping readers understand the interrelationships between metabolic pathways and the links between metabolism and the causes, preventions, and cures for human diseases.
A separate chapter is dedicated to each of the key metabolic pathways that constitute human metabolism. Each chapter features a six-part structure that facilitates a clear understanding of the metabolic processes:

• Major function(s) of the pathway.
• Tissues in which the pathway is active.
• Physiological conditions under which the pathway is most active.
• Reactions that comprise the pathway.
• Regulation of the pathway.
• Examples of human diseases related to the pathway.

Throughout the text, simple figures help readers understand how metabolic pathways and reactions work.
This text's concise, easy-to-follow approach helps readers understand and appreciate the functions, constituent reactions, and regulatory aspects of the core pathways that constitute human metabolism and are responsible for maintaining homeostasis and well-being in humans.

Contents

1. Introduction to Metabolism
2. Enzymes
3. Digestion and Absorption
4.  Glycolysis
5. Pyruvate Dehydrogenase and The Tricarboxylic Acid Cycle
6. Electron Transport and Oxidative Phosphorylation
7. The Pentose Phosphate Pathway
8. Glycogen
9. Gluconeogenesis
10. Fatty Acid Oxidation and Ketones
11. Fatty Acid Synthesis
12. Triacylglycerol Transport and Metabolism
13. Ethanol
14. Phospholipids and Sphingolipids
15. Eicosanoids
16. Glycolipids and Glycoproteins
17. Cholesterol Synthesis and Transport
18. Steroids And Bile Acids
19. Nitrogen Homeostasis
20. Amino Acids
21. Sulfur Amino Acid Metabolism
22. Folate and Vitamin B12 In One-Carbon Metabolism
23. Purines and Pyrimidines
24. Heme and Iron
25. Integration of Metabolism
26. Index 

About the Author

• Miriam D. Rosenthal, PhD, is Professor of Biochemistry and Course Director for Medical Biochemistry at Eastern Virginia Medical School. Dr. Rosenthal has extensive experience teaching and developing curricula for both medical and allied health students.
• Robert H. Glew, PhD, is Emeritus Professor of Biochemistry and Molecular Biology at the University of New Mexico Medical School. Dr. Glew has taught medical biochemistry at three medical schools in the United States and a medical school in West Africa.

Product Details

• Paperback: 440 pages
• Publisher: Wiley; 1 edition (March 30, 2009)
• Language: English
• ISBN-10: 0470122374
• ISBN-13: 978-0470122372
• Product Dimensions: 9.1 x 6.1 x 0.9 inches 

List Price: $74.95