The prevention or attenuation of the severity of disease necessitates early detection. In recent years this has been a focus relative to kidney disease. Biomarkers in Kidney Disease edited by Charles Edelstein summarizes advances in early detection and assessment of severity in an array of important kidney diseases. State of the art techniques, including metabolomics and proteomics, are discussed in areas of acute kidney injury, kidney transplantation, renal cancer, diabetic nephropathy and other glomerular diseases, as well as in preeclampsia.
Biomarkers in Kidney Disease is a seminal book, because nephrology has lagged behind other subspecialties in performing interventional trials which can improve the lives of their patients. A major reason is because the tools to detect kidney disease at the early stage have heretofore not been available. As in all diseases, prevention and attenuation of severity necessitates early intervention. The emergence of sensitive biomarkers of early kidney disease now has the potential to allow early detection and intervention.With this book there is now a source which provides up to date and important information by distinguished authors about biomarkers available to detect early kidney disease.
Biomarkers of Kidney Disease offers a thorough examination of the latest findings in the field for both the practicing physician as well as the biomedical researcher. Coverage includes biomarkers of acute kidney injury, chronic kidney disease, kidney transplant rejection, delayed kidney allograft function, renal cell cancer, glomerular disease, diabetic nephropathy, and preeclampsia. This book is the most comprehensive reference yet published on the topic of biomarkers of kidney diseases.
Contents
- Chapter 1 Characteristics of an Ideal Biomarker of Kidney Diseases
- Chapter 2 Statistical Considerations in Analysis and Interpretation of Biomarker Studies
- Chapter 3 The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools
- Chapter 4 Statistical Considerations in Analysis and Interpretation of Biomarker Studies
- Chapter 5 Biomarkers in Acute Kidney Injury
- Chapter 6 Biomarkers in Kidney Transplantation
- Chapter 7 Cystatin C as a Biomarker in Kidney Disease
- Chapter 8 Biomarkers of Renal Cancer
- Chapter 9 Urinary Proteomics and Candidate Biomarker Discovery for Diabetic Nephropathy
- Chapter 10 Biomarkers in Glomerular Disease
- Chapter 11 Biomarkers in Preeclampsia
- Index
Book Reviews
"The emergence of biomarkers to aid diagnosis, guide treatment, and provide prognosis remains one of the hot topics in nephrology. In this new book edited by Charles Edelstein, experts present the state of the art information on the current development and use of biomarkers for a wide range of kidney diseases, including acute kidney injury, glomerulonephritis and nephrotic syndrome, chronic kidney disease, and preeclampsia. I found this book well written and informative, and I would recommend this textbook to anyone interested in new approaches for diagnosing and managing subjects with kidney disease. While many of the tests are still at the level of investigation, it is heartwarming to see how much has already been done to develop quicker and more accurate ways to diagnose various kidney diseases."
By Richard J. Johnson, M.D., Temple Hoyne Buell and NKF of Colorado Endowed Professor of Medicine, Chief, Division of Renal Diseases and Hypertension, University of Colorado, Denver, USA.
"Biomarkers of Kidney Disease, edited by Charles Edelstein, is an excellent state-of-the-art summary which also includes a comprehensive account of newer biomarker discover strategies, such as metabolomics and proteomics, all illustrated by clear examples. There are timely accounts of both acute and chronic kidney diseases and the topics of cancer, diabetic nephropathy, other glomerular diseases, and pre-ecclampsia all receive careful attention. This book will be a very useful reference for both scientists and nephrologists alike."
By Professor Zoltán H. Endre, Head, Department of Medicine, University of Otago-Christchurch; Consultant Nephrologist, Christchurch Hospital; Honorary Professor of Medicine University of Queensland & Adjunct Professor University of Canterbury, New Zealand.
"Biomarkers of Kidney Disease explores both the practical and conceptual steps performed in the discovery of biomarkers in kidney disease. I highly recommend this book for anyone who wants to learn and gain insight into kidney proteomics and biomarker discovery. It will be most useful for those researchers and clinicians who study and treat kidney disease but students of biomarkers in general will also gain useful insights into this interesting field. The book covers a lot of basics and even experts will pick up a thing or two."
By Prof. Dr. Hassan Dihazi, Director Clinical Proteomics Laboratories, Nephrology & Rheumatology, University Medical Centre, Georg-August University Goettingen, Germany.
Product Details
- Hardcover: 454 pages
- Publisher: Academic Press; 1 edition (September 27, 2010)
- Language: English
- ISBN-10: 0123756723
- ISBN-13: 978-0123756725
- Product Dimensions: 9.1 x 6 x 1.1 inches
List Price: $99.95