The management of patients with an ophthalmic tumor presents particular challenges. Ophthalmic tumors are rare and diverse so that their diagnosis can be quite complex. Treatment usually requires special expertise and equipment and in many instances is controversial. The field is advancing rapidly, because of accelerating progress in tumor biology, pharmacology, and instrumentation.
Increasingly, the care of patients with an ocular or adnexal tumor is provided by a multidisciplinary team, comprising ocular oncologists, general oncologists, radiotherapists, pathologists, psychologists, and other specialists. Such expertise may only be available far from the patient’s home, in which case the local ophthalmologist will continue to be involved in the patient’s care. For all these reasons, there was scope for a textbook of ophthalmic oncology, which would amalgamate knowledge from several different disciplines, thereby helping the various specialists to understand each other better and to cooperate more efficiently.
The purpose of Clinical Ophthalmic Oncology is to provide up-to-date information of the whole spectrum of the eyelid, conjunctival, intraocular, and orbital tumors. The first section is devoted to basic principles of chemotherapy, radiation therapy, cancer epidemiology, angiogenesis, and cancer genetics. A chapter on counseling patients with ophthalmic cancer have been also included.
Special attention has been paid to make the text easily readable. Each chapter has a similar layout with boxes that highlight the key features, tables that provide comparison, and flow diagrams that outline therapeutic approaches. Several chapters authored by radiation oncologists, medical physicists, pediatric oncologists, hematologist-oncologists, and medical geneticists have been included to provide a broader perspective.
The authors followed a tight timeline to keep the contents of the book current. All 124 authors from 18 countries were gracious to accept editorial changes so as to present a balanced view of clinical practice. As evidence-based data are sparse in the field of ophthalmic oncology, it is anticipated that Clinical Ophthalmic Oncology will act as a stimulus for further thought and investigation. Readers will find as much pleasure reading this textbook.
SECTION 1: Basic principles
- 1. Principles of clinical epidemiology
- 2. Cancer etiology
- 3. Cancer pathology and angiogenesis
- 4. Cancer immunology
- 5. Cancer genetics
- 6. Principles of cryotherapy
- 7. Principles of laser therapy
- 8. Principles of radiation therapy
- 9. Ocular complications of radiotherapy
- 10. Principles of chemotherapy
- 11. Counseling patients with cancer
SECTION 2: Eyelid tumors
- 12. Examination techniques
- 13. Classification and differential diagnosis of eyelid tumors
- 14. Benign epidermal tumors
- 15. Basal cell carcinoma
- 16. Squamous cell carcinoma
- 17. Sebaceous gland carcinoma
- 18. Melanoma of the eyelid
- 19. Eyelid adnexal tumors
- 20. Eyelid stromal tumors
- 21. Surgical techniques
- 22. Systemic associations of eyelid tumors
SECTION 3: Conjunctival and corneal tumors
- 23. Examination techniques, classifi cation,and differential diagnosis of conjunctival and corneal tumors
- 24. Benign conjunctival tumors
- 25. Ocular surface squamous neoplasia
- 26. Primary acquired melanosis
- 27. Conjunctival melanoma
- 28. Conjunctival stromal tumors
- 29. Surgical techniques
- 30. Systemic associations of conjunctival and corneal tumors
SECTION 4: Uveal tumors
- 31. Examination techniques
- 32. Diagnostic techniques
- 33. Classification of uveal tumors
- 34. Tumors of the uvea: benign melanocytic tumors
- 35: Uveal malignant melanoma: epidemiologic aspects
- 36. Uveal malignant melanoma: clinical features
- 37. Uveal malignant melanoma: differential diagnosis
- 38. Uveal malignant melanoma: histopathologic features
- 39. Management of patients with uveal melanoma
- 40. Uveal malignant melanoma: management options – thermotherapy
- 41. Uveal malignant melanoma: management options – brachytherapy
- 42. Uveal malignant melanoma: management options – proton beam radiotherapy
- 43. Uveal malignant melanoma: management options – stereotactic radiotherapy
- 44. Uveal malignant melanoma: management options – resection techniques
- 45. Uveal malignant melanoma: COMS results
- 46. Uveal malignant melanoma: prognostic factors
- 47. Uveal malignant melanoma: mortality
- 48. Uveal malignant melanoma: metastasis
- 49. Uveal vascular tumors
- 50. Uveal neural tumors
- 51. Uveal osseous tumors
- 52. Uveal myogenic, fi brous, and histiocytic tumors
- 53. Uveal lymphoproliferative tumors
- 54. Uveal metastatic tumors
- 55. Intraocular manifestations of proliferative hematopoietic disorders
- 56. Intraocular biopsy
SECTION 5: Tumors of the retina and retinal pigment epithelium
- 57. Retinal vascular tumors
- 58. Coats’ disease
- 59. Retinal astrocytic tumors
- 60. Tumors of the retinal pigment epithelium
- 61. Tumors of the ciliary pigment epithelium
- 62. Lymphoma of the retina and CNS
- 63. Ocular paraneoplastic diseases
- 64. Neuro-oculocutaneous syndromes (phakomatoses)
SECTION 6: Retinoblastoma
- 65. Retinoblastoma and cancer genetics
- 66. Cellular and genetic events in retinoblastoma tumorigenesis
- 67. Geographic and environmental factors
- 68. Retinoblastoma: an international perspective
- 69. Staging and grouping of retinoblastoma
- 70. Heritable retinoblastoma: the RB1 cancer predisposition syndrome
- 71. Non-ocular tumors
- 72. Trilateral retinoblastoma
- 73. Retinoblastoma: genetic testing and counseling
- 74. Chemotherapy for retinoblastoma: an overview
- 75. Local therapy, brachytherapy, and enucleation
- 76. Teletherapy: indications, risks, and new delivery options
- 77. Histopathologic features and prognostic factors
- 78. Orbital retinoblastoma
- 79. Metastatic retinoblastoma
- 80. Retinocytoma or retinoma
- 81. Children’s Oncology Group (COG) Trials for Retinoblastoma
- 82. Retinoblastoma: at risk pregnancies
- 83. Future directions
SECTION 7: Orbital tumors
- 84. Examination techniques
- 85. Imaging techniques
- 86. Classification of orbital tumors
- 87. Evaluation of a child with orbital tumor
- 88. Evaluation of an adult with orbital tumor
- 89. Non-specific orbital inflammation
- 90. Vascular orbital tumors
- 91. Benign tumors of the orbit
- 92. Tumors of the optic nerve
- 93. Tumors of the lacrimal gland
- 94. Tumors of the lacrimal sac
- 95. Orbital and adnexal lymphoma
- 96. Malignant tumors of the orbit
- 97. Rhabdomyosarcoma
- 98. Enucleation and orbital implants
- 99. Principles of orbital surgery
Index
Book Details
- Hardcover: 628 pages
- Publisher: Saunders (March 22, 2007)
- Language: English
- ISBN-10: 1416031677
- ISBN-13: 978-1416031673
- Product Dimensions: 10.9 x 9 x 1.6 inches
List Price: $248.00