Welcome to the twelfth edition of Williams Textbook of Endocrinology. Robert Williams inaugurated this enduring textbook more than 50 years ago, and the goals have remained essentially unchanged (i.e., to publish “a condensed and authoritative discussion of the management of clinical endocrinopathies based upon the application of fundamental information obtained from chemical and physiological investigation”). Of course, today we would add results of cellular and genomic investigation, as well as the wealth of clinical trial data, as aids in clinical management. The immense and often overwhelming body of new information from multiple disciplines, in fact, makes this synthetic endeavor more relevant than ever to help guide endocrinologists in the care of their patients. To encourage the goal of both highest quality scientific rigor and knowledge synthesis, we continue to ask the most distinguished authors to synthesize entire areas of clinical endocrine science. The mandate for concise yet authoritative and comprehensive presentations acknowledges both the time pressures on today's physicians and the desire to make the text affordable and easily navigated.
This edition has involved extensive revisions of the previous text, and 22 new authors have joined our expert faculty. A uniform style facilitates identification and ready use of clinical algorithms.
We express our deep gratitude to the co-workers in our offices: Anita Nichols, Lynn Moulton, Grace Labrado, Louise Ishibashi, and Sherri Turner, whose energetic efforts have made this work possible. We also thank our colleagues at Elsevier—Joan Ryan, Pamela Hetherington, and Dolores Meloni—who skillfully navigated the dynamic world of medical publishing while assuring achievement of our goals. Their efforts have been essential in ensuring the successful publication of this high-quality textbook, which has become the classic text for all professionals engaged in caring for patients with endocrine disorders.
Finally, we would like to recognize and congratulate Dr. Melvin Grumbach for his outstanding contributions to Williams Textbook of Endocrinology, beginning with the fourth edition that was published in 1968.
- Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, Henry M. Kronenberg
The latest edition of Williams Textbook of Endocrinology edited by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, helps you diagnose and treat your patients effectively with up-to-the minute, practical know-how on all endocrine system disorders. Comprehensive yet accessible, this extensively revised 12th Edition updates you on diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more so you can provide your patients with the most successful treatments. Find scientific insight and clinical data interwoven in every chapter, reflecting advances in both areas of this constantly changing discipline, and presented in a truly accessible format. You'll also access valuable contributions from a dynamic list of expert authors and nearly 2.000 full-color images to help you with every diagnosis.
Along with convenient online access at www.expertconsult.com, this title has everything you need to manage any and all the clinical endocrinopathies you may encounter.
Book Features
- Rely on the one reference that integrates rapidly evolving basic and clinical science in a cohesive, user-friendly format, definitively addresses every topic in the field, and has remained a standard for more than half a century.
Website Features
- Consult the book from any computer at home, in your office, or at any practice location.
- Instantly locate the answers to your clinical questions via a simple search query.
- Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
New to this edition
- Update your know-how and skills to diagnose and treat your patients most effectively with exhaustively revised content on diabetes, metabolic disease, thyroid cancer, fertility problems, testicular problems, weight issues, and much more.
- Apply reliable guidance on endocrine conditions of growing interest like hypothyroidism and testicular disorders, with dedicated new chapters that expound on the latest research findings.
- Overcome any clinical challenge with comprehensive and easy-to-use coverage of everything from hormone activity, diagnostic techniques, imaging modalities, and molecular genetics, to total care of the patient.
- Apply the latest practices with guidance from expert authors who contribute fresh perspectives on every topic.
- Search the full contents online, download all the images, and access hyperlinked references to PubMed at www.expertconsult.com.
Contents
Section I - Hormones and Hormone Action
- CHAPTER 1 - Principles of Endocrinology
- CHAPTER 2 - Clinical Endocrinology
- CHAPTER 3 - Genetic Control of Peptide Hormone Formation
- CHAPTER 4 - Mechanism of Action of Hormones That Act on Nuclear Receptors
- CHAPTER 5 - Mechanism of Action of Hormones That Act at the Cell Surface
- CHAPTER 6 - Laboratory Techniques for Recognition of Endocrine Disorders
Section II - Hypothalamus and Pituitary
- CHAPTER 7 - Neuroendocrinology
- CHAPTER 8 - Pituitary Physiology and Diagnostic Evaluation
- CHAPTER 9 - Pituitary Masses and Tumors
- CHAPTER 10 - Posterior Pituitary
Section III - Thyroid
- CHAPTER 11 - Thyroid Physiology and Diagnostic Evaluation of Patients with Thyroid Disorders
- CHAPTER 12 - Thyrotoxicosis
- CHAPTER 13 - Hypothyroidism and Thyroiditis
- CHAPTER 14 - Nontoxic Diffuse and Nodular Goiter and Thyroid Neoplasia
Section IV - Adrenal Cortex and Endocrine Hypertension
- CHAPTER 15 - The Adrenal Cortex
- CHAPTER 16 - Endocrine Hypertension
Section V - Reproduction
- CHAPTER 17 - Physiology and Pathology of the Female Reproductive Axis
- CHAPTER 18 - Hormonal Contraception
- CHAPTER 19 - Testicular Disorders
- CHAPTER 20 - Sexual Dysfunction in Men and Women
Section VI - Endocrinology and the Life Span
- CHAPTER 21 - Endocrine Changes in Pregnancy
- CHAPTER 22 - Endocrinology of Fetal Development
- CHAPTER 23 - Disorders of Sex Development
- CHAPTER 24 - Normal and Aberrant Growth
- CHAPTER 25 - Puberty
- CHAPTER 26 - Hormones and Athletic Performance
- CHAPTER 27 - Endocrinology and Aging
Section VII - Mineral Metabolism
- CHAPTER 28 - Hormones and Disorders of Mineral Metabolism
- CHAPTER 29 - Metabolic Bone Disease
- CHAPTER 30 - Kidney Stones
Section VIII - Disorders of Carbohydrate and Metabolism
- CHAPTER 31 - Type 2 Diabetes Mellitus
- CHAPTER 32 - Type 1 Diabetes Mellitus
- CHAPTER 33 - Complications of Diabetes Mellitus
- CHAPTER 34 - Hypoglycemia
Section IX - Body Fat and Lipid Metabolism
- CHAPTER 35 - Neuroendocrine Control of Energy Stores
- CHAPTER 36 - Obesity
- CHAPTER 37 - Disorders of Lipid Metabolism
- CHAPTER 38 - Endocrinology of HIV/AIDS
- CHAPTER 39 - Gastrointestinal Hormones and Gut Endocrine Tumors
Section X - Polyendocrine and Neoplastic Disorders
- CHAPTER 40 - Pathogenesis of Endocrine Tumors
- CHAPTER 41 - Multiple Endocrine Neoplasia
- CHAPTER 42 - The Immunoendocrinopathy Syndromes
- CHAPTER 43 - Endocrine Management of the Cancer Survivor
- CHAPTER 44 - Neuroendocrine Gastrointestinal and Lung Tumors (Carcinoid Tumors), Carcinoid Syndrome, and Related Disorders
Product Details
- Hardcover: 1904 pages
- Publisher: Saunders; 12 edition (June 15, 2011)
- Language: English
- ISBN-10: 1437703240
- ISBN-13: 978-1437703245
List Price: $189.00