During the past 30 years, phototherapy has greatly influenced treatment concepts in dermatology. Consequently, photomedicine has developed from empiricism into one of the most exciting fields in biomedical research. Studies on the effects of visible and ultraviolet radiation on skin have led to a fruitful collaboration between basic scientists and clinicians. Thus, phototherapy may be regarded as a prime example of applied skin biology. UV radiation has been used for decades in the management of common skin diseases such as psoriasis and atopic dermatitis. More recently, the introduction of selective spectra in the UVB and UVA range, such as narrowband UVB and UVA-1 phototherapy, as well as the inclusion of new indications, has much stimulated the interest in photodermatology. Visible light in combination with photosensitizers is currently in use for diagnosis and treatment of selected tumours. Extracorporeal photochemotherapy has proven to be effective beyond dermatology, in particular in transplantation medicine. Most phototherapeutic regimes have been developed empirically and without knowledge about the biological mechanisms involved. Recent progress in the understanding of basic photobiological principles has made phototherapy more effective and, even more importantly, safer at the same time.
The second edition of this handbook takes this dualism into account by presenting clinical information on the background of current knowledge of photobiological principles. Besides the detailed description of photo- and photochemotherapy for selected skin diseases, this volume contains standardized test protocols for photodermatoses and the diagnosis of skin tumours.
There exists a variety of phototherapeutic modalities, and clinicians can now select the therapy of choice. A specific disease can thus be treated with the regimen that fits best the particular situation of a given patient. Therefore, the major focus of this volume is on the use of different treatment modalities for a specific disease. The clinically oriented chapters are supplemented by practical guidelines for phototherapy that have proven successful over many years. Again, the leading experts have contributed to this project. Most of the authors are not only experienced clinical photodermatologists but also internationally renowned experts in basic photobiological research. This monograph will continue to serve as the state-of-the-art reference for dermatological phototherapy and photodiagnostic methods in daily practice, clinical settings, and research.
Contents
Part I Basic Mechanisms in Photo(chemo)therapy
- 1 UV Radiation, Irradiation, and Dosimetry
Part II Photo(chemo)therapy in Daily Practice
- 2 Mechanisms of Photo(chemo)therapy
- 3 Photo(chemo)therapy for Psoriasis
- 4 Photo(chemo)therapy for Atopic Dermatitis
- 5 Phototherapy and Photochemotherapy of the Idiopathic Photodermatoses
- 6 Photo(chemo)therapy for Cutaneous T-Cell Lymphoma
- 7 Phototherapeutic Options for Vitiligo
- 8 Photo(chemo)therapy of Graft-versus-Host Disease (GvHD)
- 9 Phototherapy and Photochemotherapy: Less Common Indications for Use
- 10 Phototherapy and HIV Infection
Part III Special Phototherapeutic Modalities
- 11 Photodynamic Therapy in Dermatology
- 12 Extracorporeal Photoimmunochemotherapy
- 13 Ultraviolet A-1 Phototherapy: Indications and Mode of Action
Part IV Photoprotection in Daily Practice
- 14 Acute and Chronic Photodamage from Phototherapy, Photochemotherapy, and Solar Radiation
- 15 Photoprotection
Part V Photodiagnostic Procedures in Daily Practice
- 16 Photodiagnostic Modalities
- 17 The Photopatch Test
- 18 Fluorescence Diagnosis in Dermatology
- 19 Practical Guidelines for Broadband UVB, Narrowband UVB, UVA-1 Phototherapy, and PUVA Photochemotherapy - A Proposal
- 20 Technical Equipment
Subject Index
Product Details
- Authors: Jean Krutmann, Herbert Hönigsmann and Craig A. Elmets
- Hardcover: 464 pages
- Publisher: Springer; 2nd edition (December 16, 2008)
- Language: English
- ISBN-10: 354036692X
- ISBN-13: 978-3540366928
- Product Dimensions: 9.4 x 6.4 x 1 inches
List Price: $139.00