Hosenpud: Congestive Heart Failure 3rd Edition

Congestive Heart Failure is a comprehensive, state-of-the-art reference on all basic and clinical aspects of heart failure.

Having first decided to organize and edit a book on heart failure in 1992 (with a 1994 publication date), we have been astounded at the changes in the field over a relatively brief 14-year period. It is with some amusement that we now look back at our first edition and note a combined chapter of beta agonists and antagonists, a separate chapter on phosphodiesterase inhibitors, and an extensive discussion of antiarrhythmic therapy in congestive heart failure (CHF) with only a brief mention of implantable defibrillators. On the other hand, it is somewhat disheartening to see that the majority of our advances over this period have come from very generic approaches to CHF, with much less progress in interfering with underlying etiologies. Nonetheless, we continue to move forward on a broad front with an expanded view of the genetics of primary cardiac muscle disease, better imaging techniques, routine screening blood testing, and standardization of medical management. We have the addition of new agents to the therapeutic armamentarium, widespread use of prophylactic defibrillators, and several novel approaches, including biventricular pacing, continuous flow ventricular assist technology, and cellular transplantation.

The fact that both our understanding and treatment of heart failure continue to evolve at a rapid rate is the real motivation that led us to move forward with the third edition of Congestive Heart Failure. As with the first two editions, the aim is to provide a comprehensive overview of heart failure and to point out areas where future advances are likely. Again, the text is geared to both the scientist and clinician with the hope that each will find the broad base of information valuable in some way in their respective daily activities.

We would like to acknowledge the excellent contributions of our authors, who not only supplied these chapters in a timely fashion but who were so responsive to editorial comments and revisions. Their professionalism, inquisitiveness, and enthusiasm made our role a joy rather than a burden. Finally, the loving support and encouragement of our families in this and all our other professional endeavors has been instrumental in whatever success we have achieved.

Jeffrey D. Hosenpud MD and Barry H. Greenberg MD

Congestive Heart Failure features up-to-date chapters on:

• Impact and treatment of comorbidities
• Prevention of sudden cardiac death
• Rationale for use of anticoagulants
• Ultrafiltration
• Use of mechanical devices
• Gene and cell therapy

Contents
Section I Epidemiology and Pathophysiology of Heart Failure

• Epidemiology of Heart Failure
• Cellular and Molecular Abnormalitites in Failing Cardiac Myocytes
• Determinants of Cardiac Remodeling and Progression to Heart Failure
• Cytoskeletal Abnormalities in Cardiocytes During Heart Failure
• Abnormalities in Calcium Cycling in Heart Failure
• Abnormalities in Cardiac Contraction: Systolic Dysfunction
• Heart Failure with Normal Ejection Fraction
• Cellular, Molecular, and Structural Changes During Cardiac Remodeling
• Remodeling of the Cardiac Interstitium in Heart Failure
• The Renin-Angiotensin System
• Sympathetic Nervous System in Heart Failure
• Other Neurohormonal Systems
• Cytolines as Mediators of Disease Progression in the Failing Heart
• The Peripheral Circulation in Heart Failure
• The Kidney in the Heart Failure

Section II Differential Diagnosis of Congestive Heart Failure

• Risk Factors for Heart Failure
• Heart Failure Secondary to Coronary Artery Disease
• The Cardiomyopathic and Inflammatory Diseases
• Congestive Heart Failure as a Consequence of Valvular Heart Disease
• Congestive Heart Failure Secondary to Congenital Heart Disease
• Right Heart Failure
• Heart Failure in Cardiac Tamponade, Constrictive Pericarditis, and Restrictive Cardiomyopathy

Section III Pharmacologic Therapy of Heart Failure

• Clinical Pharmacokinetics in Congestive Heart Failure
• Traditional Diuretics and Other Diuresing Agents
• Digital Glycosides
• Inhibition of the Renin-Angiotensin-Aldostrone System in Chronic Heart Failure: Rationale, Results, and Current Recommendations
• Vasodilators
• Beta-Blocker Therapy for Heart Failure
• Inotropic Agents

Section IV Clinical Approach to Acute and Chronic Heart Failure

• Primary Prevention of Heart Failure
• Physical Examination in Heart Failure
• Natriuretic Peptides as Biomakers to Detect, Risk-Stratify, and Manage Patients with Heart Failure
• Noninvasive Imaging Techniques for the Assessment of the Patient with Heart Failure
• Management of Acute and Decompensated Heart Failure
• The Medical Management of Chronic Heart Failure in Patients with Systolic Dysfuction
• Biventricular Pacing in Congestive Heart Failure
• The Heart Failure Clinic
• Exercise and Rehabilitation in Congestive Heart Failure
• Impact and Treatment of Comorbidities in Heart Failure
• Management fo Supraventricular Arrhythmias in Patients with Heart Failure
• Prevention of Sudden Death in Heart Failure
• Pathogenesis and Therapy of Thrombosis in Patients with Congestive Heart Failure
• Ultrafilitration Therapies for Congestive Heart Failure
• Surgical Approaches to Patients with Chronic Congestive Heart Failure
• Use of Mechanical Devices in Treating Heart Failure
• Cardiac Transplantation
• Strategies for Gene and Cell Therapy in Heart Failure
• End-of-Life Considerations
• Future Directions

Product Details

Hardcover: 845 pages

Publisher: Lippincott Williams & Wilkins; Third edition (2007)

Language: English

ISBN: 0781762855 / 978-0781762854  

List Price: $184.00