Lecture Notes: Conditions associated with elevated chromogranin A







Gastroenteropancreatic neuroendocrine tumors
  • Carcinoid tumors
  • Islet cell tumors (eg, gastrinomas, VIPomas, somatostatinomas, glucagonomas)
Endocrine disease
  • Hyperparathyroidism
  • Hyperthyroidism
  • Pheochromocytoma
  • Pituitary tumors
  • Medullary thyroid carcinoma
Gastrointestinal disorders
  • Chronic atrophic gastritis
  • Chronic hepatitis
  • Colon cancer
  • Hepatocellular carcinoma
  • Inflammatory bowel disease
  • Irritable bowel syndrome
  • Liver cirrhosis
  • Pancreatic adenocarcinoma
  • Pancreatitis
Cardiovascular disease
  • Acute coronary syndrome
  • Arterial hypertension
  • Cardiac insufficiency/failure
  • Essential hypertension
  • Giant cell arteritis
Drugs
  • Histamine-2 receptor antagonists
  • Proton pump inhibitors
Inflammatory disease
  • Airway obstruction in smokers
  • Chronic bronchitis
  • Systemic rheumatoid arthritis
  • Systemic inflammatory response syndrome
Renal disorders
  • Renal insufficiency / failure
Non-gastrointestinal cancers
  • Breast cancer
  • Ovarian cancer
  • Prostate cancer
  • Small cell lung cancer 
 

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