Companion to Peripheral Neuropathy is an extension of Peripheral Neuropathy, first to fourth editions, originally published by W.B. Saunders and then by Elsevier, Inc. Peripheral Neuropathy met the need for a comprehensive review of peripheral nerve neurobiology, pathology, and clinical disorders. P.K. Thomas, a co-editor of Peripheral Neuropathy, developed an incapacitating stroke during the preparation of the fourth edition and therefore could not participate in Companion to Peripheral Neuropathy. Thomas was an internationally renowned expert on peripheral nerve. He had a breadth of information and skill in writing and editing that we miss.
There were three developments that led to production of Companion to Peripheral Neuropathy. The first was introduction of magnetic resonance imaging (MRI)–targeted fascicular nerve biopsy pioneered especially by three of the editors of this book (PJBD, KA, and RJS). The approach allows accurate anatomic localization and MRI characterization of focal nerve lesions identified by clinical and neurophysiologic studies. In appropriately chosen cases this further localization and characterization leads to surgical exposure, fascicular nerve biopsy, and pathologic identification of the pathologic process. As we demonstrate in this book, this frequently allows diagnosis not otherwise possible. However, as Jack Griffin said in discussing MRI-targeted fascicular nerve biopsy in a plenary session of the AAN, “Don't do this at home.” We infer that he saw the importance of the newly introduced approaches but warned against its misuse, recognizing that considerable harm could be done.
The second development relates to improved detection, characterization, and quantitation of autonomic and sensory dysfunction using quantitative testing approaches (i.e., qualitative autonomic testing [QAT] and quantitative sensory testing [QST]). The techniques described emphasize standard performance of tests and use of validated algorithms of testing approaches to arrive at accurate results. Also, we emphasize use of reference values based on study of large representative healthy subject cohorts with values corrected for age, gender, and anthropomorphic variables. We explain and describe the value of using sum scores of attributes of nerve conduction expressed as normal deviates from percentiles corrected for applicable variables, for example, S 5 NC nds ≥ 95th percentile or S 7 NTs nds ≥ 95th for this purpose. The third reason, and perhaps of greatest importance to some readers, is the inclusion of information on new disorders, insights, and treatments that have come to light since the publication of the fourth edition of Peripheral Neuropathy.
Chapters have been grouped under four headings: MRI–Targeted Fascicular Nerve Biopsy; Diagnostic Case Reports; Autonomic Disorders; and Scientific Reports, the latter includes new molecular genetic insights.
Key Features
- Offers new insights in clinical and electrophysiologic characterization, imaging, histopathology, and molecular genetics
- Shows you how abstract diagnosis and management principles apply in real situations
- Presents more illustrations than any competing reference so you can see disorders as they present in practice
- Offers expert clues to help you diagnose and manage patients quickly and effectively
- Provides references to the most significant literature in the field so you can stay at the forefront of this science
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Contents
SECTION ONE - MRI--Targeted Fascicular Nerve Biopsy
- 1 - MRI–Targeted Fascicular Nerve Biopsies of Proximal Nerves: Historic Reports and Illustrative Case Reports
- 2 - Techniques for Magnetic Resonance Imaging of Peripheral Nerves: Diagnosis and Guidance for Targeted Fascicular Nerve Biopsy
- 3 - Targeted Fascicular Biopsy: A Surgical Perspective
- 4 - The “Tail” of the Tibial Intraneural Ganglion
- 5 - Inflammatory Multifocal Encephalomyelopolyradiculoneuropathy Mimicking a Granulomatous or Lymphomatous Process
- 6 - Sensory Ataxia with Normal Nerve Conduction--Chronic Inflammatory Sensory Polyradiculopathy (CISP)
- 7 - Pathology May Distinguish Two Causes of Localized Motor Neuropathy: Multifocal Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy
- 8 - Coexisting Inherited and Acquired Neuropathy in the Same Patient (Charcot-Marie-Tooth Type 1 and Castleman's Disease)
- 9 - Median Mononeuropathy -- Glomangioma
- 10 - Clinical and Neuropathological Characteristics of Peripheral Nerve Lymphoma
- 11 - Neurolymphomatosis Presenting with Asymmetric Polyradiculoneuropathy and Multiple Cranial Neuropathies
- 12 - Malignant Peripheral Nerve Sheath Tumor
- CHAPTER 13 - An Unusual Case of Pia-Arachnoiditis due to Metastatic Breast Carcinoma
- CHAPTER 14 - Painful Enlargement of the Lumbosacral Plexus -- Prostate Cancer with Perineural Spread
- CHAPTER 15 - Granulocytic Sarcoma Presenting as a Recurrent, Multifocal Radiculoplexopathy
- CHAPTER 16 - 42-Year-Old Man with Biphasic Synovial Sarcoma
SECTION TWO - Diagnostic Case Reports
- 17 - Acute Paraplegia -- Saddle Embolism of Abdominal Aorta
- 18 - Evaluation of Radial Neuropathy: Conduction Block as a Marker of Acute Compressive Injury
- 19 - Painful Injury Neuroma from Surgical Suture Granuloma
- 20 - Unilateral Leg Pain and Footdrop: Synovial Cyst Revealed by Ultrasound
- 21 - Disseminated Sporotrichosis with Multiple Granulomatous Mononeuropathies
- CHAPTER 22 - Hot and Cold Feet -- Sensory Neuropathy Associated with Human Immunodeficiency Virus
- 23 - Borrelia Neuropathy with Necrotizing Vasculitis
- 24 - A Possible Case of Ciguatoxin Exposure
- 25 - Stepwise Facial and Upper Limb Weakness and Small Fiber Sensory Loss -- Tangier Disease
- 26 - Adrenomyeloneuropathy Masquerading as Charcot-Marie-Tooth Disease
- 27 - "Small-Fiber" Neuropathy, Angiokeratoma, and Heat Intolerance -- Fabry's Disease
- 28 - A Distinct Neuropathy with Hypotonia, Kinky Hair, and Axonal Spheroids -- Giant Axonal Neuropathy
- 29 - Gait Imbalance, Urinary Urgency, and Mild Cognitive Dysfunction - A Case of Adult Polyglucosan Body Disease
- CHAPTER 30 - Late-Onset Transthyretin Val30Met Familial Amyloid Polyneuropathy Unrelated to Endemic Foci
- 31 - Neurologic Improvement After Cervical Decompression in Wild Type Transthyretin Amyloidosis
- 32 - A Gentleman with Deteriorating Golf Handicap -- Transthyretin Amyloid Polyneuropathy
- 33 - Asymmetrical Rapidly Progressing Sensorimotor Neuropathy in an Old Man -- Transthyretin Amyloidosis
- 34 - Corneal Lattice Dystrophy, Facial Weakness and Sensorimotor Polyneuropathy--Gelsolin Amyloidosis
- 35 - Chronic Inflammatory Demyelinating Polyradiculoneuropathy -- Like Neuropathy with Gastrointestinal Dysmotility, Ophthalmoplegia, and Leukoencephalopathy -- Mitochondrial Neurogastrointestinal Encephalopathy
- 36 - Neurogastrointestinal Encephalomyopathy: A Demyelinating Disorder of Nerves
- 37 - Focal Mononeuropathy Onset of Amyotrophic Lateral Sclerosis
- 38 - Late Sporadic CMT4C -- A New KIAA1985 Mutation
- 39 - Charcot-Marie-Tooth 4C Associated with a Novel Homozygous Mutation
- 40 - Chronically Tardy: Hereditary Liability to Pressure Palsy Presenting with Ulnar Neuropathy at the Elbow
- 41 - Peroneal Mononeuropathy from Sarcoidosis
- 42 - Postsurgical Inflammatory Lumbosacral Plexopathy
- 43 - Inflammatory Polyradiculoneuropathy, Likely Related to Pork Processing Occupation
- 44 - Multifocal Motor Neuropathy: Recovery After 107 Six-Weekly Infusions of High Dose Immunoglobulin
- 45 - A Case of Guillain-Barre Syndrome Associated with Anti-GD1b Immunoglobulin G Antibodies
- 46 - A Weak, and Numb Patient with Tremor -- Antimyelin-Associated Glycoprotein Polyneuropathy
- 47 - Chronic Immune Sensory Polyneuropathy Responding to Immunotherapy
- 48 - Multifocal Motor Neuropathy Without Overt Conduction Block
- 49 - A Chronic Neuropathy with Tremor and Paraproteinemia
- 50 - Sarcoid Polyradiculoneuropathy Unresponsive to Corticosteroids
- 51 - Copper Deficiency Myeloneuropathy
- 52 - Severe Sensorimotor Radiculoplexus Neuropathy Following Bariatric Surgery
- 53 - Hemorrhagic Quadriplegic Polyneuropathy
- 54 - Reversible Upper and Lower Motor Neuron Disease Persisting Long After Infliximab Therapy
- 55 - Predominant Peripheral Nerve Involvement in AL Amyloidosis
- 56 - Meningeal Enhancement in POEMS Syndrome: Another Clinical Sign of Vascular Endothelial Growth Factor Overactivity?
- 57 - POEMS Syndrome
- 58 - Multiple Mononeuropathy and B-Cell Lymphoma: Hepatitis C Polyneuropathy
- 59 - Chronic Lymphocytic Leukemia Causing Multiple Mononeuropathies
- 60 - Asymmetric Peripheral Neuropathy and Visual Loss -- Intraneural Perineurioma and Optic-Nerve-Sheath Meningioma
SECTION THREE - Autonomic Disorders
- 61 - A Case of Dopamine-Beta-Hydroxylase Deficiency, a Limited Adrenergic Neuropathy: Treatment with L-DOPS
- 62 - Subacute Immune Sensory and Autonomic Neuropathy Following a Cytomegalovirus Infection
- 63 - Immune Trigeminal Sensory Neuropathy with Esophageal Dysmotility
- 64 - A Case of Autoimmune Autonomic Ganglionopathy
- 65 - Autoimmune Autonomic Ganglionopathy: Response to Immunomodulatory Therapy
- 66 - Autoimmune Autonomic Ganglionopathy -- a Case Refractory to First-Line Symptomatic Treatment
- 67 - The Case of the Red, Hot, Painful Feet -- Erythromelalgia
- 68 - Characteristic Sudomotor Abnormalities in Lepromatous Leprosy
- 69 - Bilateral Phrenic Nerve Injury Following Radiofrequency Catheter Ablation for Atrial Fibrillation
- 70 - Radiation-Induced Baroreflex Failure
SECTION FOUR - Scientific Reports
- 71 - How Far Have We Come in Prevention and Treatment of Peripheral Neuropathy?
- 72 - Length-Related Axonal Loss in Neuropathy
- 73 - Schwann Cell Investment of Unmyelinated Nerve Fiber
- 74 - The AAN Case Definition for Distal Symmetric Polyneuropathy
- 75 - Evaluation of Diabetic Polyneuropathy: Design of the Neurologic Examination Versus Clinical Neurophysiology Tests Trial
- 76 - Testing of Touch-Pressure Sensation: Introduction of the Touch-Pressure Sensogram
- 77 - Thermal Disk Quantitative Sensation Testing of Cooling Discrimination
- 78 - Genes and Inherited Neuropathies
- 79 - Role of High-Resolution Imaging in Patients with Painful Lumbosacral Plexopathy
- 80 - Amyloidosis Typing Based on Laser Microdissection and Mass Spectrometry of Paraffin-Embedded Tissue Biopsies
About the Editors
- Peter J. Dyck, MD, Professor of Neurology, Roy E. and Merle Meyer Professor of Neuroscience, Mayo Clinic College of Medicine, Head of the Peripheral Nerve Research Laboratory, Consultant in Neurology, Department of Neurology, Mayo Clinic, Rochester, Minnesota.
- P. James B. Dyck, MD, Associate Professor of Neurology, Head of the Peripheral Nerve Laboratory and Peripheral Nerve Section, Department of Neurology, Mayo Clinic, Rochester, Minnesota.
- JaNean K. Engelstad, HT, Peripheral Nerve Research Laboratory, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota.
- Phillip A. Low, MD, Robert D. and Patricia E. Kern Professor of Neurology, Mayo Clinic College of Medicine, Consultant Department of Neurology, Mayo Clinic, Rochester, Minnesota.
- Kimberly K. Amrami, MD, Professor of Radiology, Department of Radiology, Mayo Clinic College of Medicine, Consultant in Radiology and Neurologic Surgery, Chair, Division of Body MRI, Mayo Clinic, Rochester, Minnesota.
- Robert J. Spinner, MD, Professor Departments of Neurological Surgery, Orthopedics, and Anatomy, Mayo Clinic, Rochester, Minnesota.
- Christopher J. Klein, MD, Associate Professor of Neurology, Department of Neurology, Mayo Clinic, Rochester, Minnesota.
Product Details
- Hardcover: 432 pages
- Publisher: Saunders; 1 Har/Psc edition (2011)
- Language: English
- ISBN-10: 1437700012
- ISBN-13: 978-1437700015
- Product Dimensions: 11.1 x 8.7 x 0.8 inches
List Price: $174.00