Hoffbrand: Color Atlas of Clinical Hematology 4th edition

Since the previous edition was published in 2000, major advances have occurred in the understanding of the molecular basis of hematological diseases. The World Health Organization (2008) Classification of Hematological Malignancies has incorporated this new knowledge to define many of these diseases and to add new entities. Molecular genetics are also now used more widely to classify benign disorders such as the thalassemias, inherited bone marrow failure syndromes, iron refractory iron deficiency anemia, hemochromatosis, and inherited coagulation disorders. We have attempted to fully illustrate this new knowledge in the fourth edition of the Color Atlas of Clinical Hematology. Scientific diagrams, images of cytogenetics, fluorescent in-situ hybridization (FISH), and gene arrays are included throughout. Fluorescent-activated cell sorting (FACS) and new imaging techniques, including FDG-PET, widely used in the diagnosis of Hodgkin and non-Hodgkin lymphoma, are also extensively included.
The two original authors have been joined for this edition by Dr. Paresh Vyas from the Weatherall Institute of Molecular Medicine; Dr. Vyas has taken responsibility for the first three chapters, which deal with the basic science of blood formation, including cell machinery, cellular aspects of hematopoiesis, and growth factors. We give only brief descriptions of therapy and have omitted the section from the previous edition on fine needle aspirate (FNA) appearances in nonhematological disease since FNA has now largely been replaced by tru-cut biopsy in hematological practice.
We thank the many colleagues throughout the world who have generously provided images. They are acknowledged on the individual figures. We particularly thank Dr. Elisabeth Nacheva and Dr. Wendy Erber for many cytogenetic, FISH, FACS, and hematopathology images, without which the book would have been incomplete. Professor Elias Campo came to our rescue when we needed many additional figures to comprehensively illustrate the new WHO 2008 classification of lymphomas, and we thank him and Professor Elaine Jaffe for giving us access to the provisional 2008 WHO classification prior to its publication. Professor Peter Isaacson and Dr. Alan Ramsay have also generously given many immunohistological images. We are sad that Professor David Mason, an outstanding hematopathologist and colleague, who was a major contributor to the Atlas in the third edition, died in 2008.
We are grateful to our Publishers and particularly Dolores Meloni, Michael Troy, Joan Sinclair, and John Ormiston for their unstinting help in assembling this vast amount of complex material into its final form. We are grateful to Jane Fallows for her expert scientific diagrams and the Department of Medical Illustration, Royal Free Hospital for expertise in assembling many electronic images into a publishable form. They have all been remarkably patient during our multiple additions and updating. We are also grateful to Avril van der Loo, who expertly typed and retyped the majority of the chapters.
We hope this book in its printed and electronic versions will be used as a comprehensive, up-to-date illustrated encyclopedia of blood diseases. We would be grateful to receive offers of new images for future editions and also advice if any errors or omissions have occurred in what has been an immense task.

A. Victor Hoffbrand, John E. Pettit

Key Features

• Helps you solve difficult diagnostic challenges using highly illustrated, full-color guidance to the recognition of signs in blood cells.
• Shows complex principles more clearly with explanatory illustrations and tables.
• Explores the pathogenesis, clinical, morphologic, and investigational aspects of blood disease with extensive coverage of the pathologic anatomy of common clinical entities.
• Provides quick and easy reference of key diagnostic issues in a comprehensive yet concise format.

Website Features

• Consult the book from any computer at home, in your office, or at any practice location.
• Instantly locate the answers to your clinical questions via a simple search query.
• Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
• Images: Browse a Library of all book images. Easily select, organize, and download your images into a presentation.

Contents 

• Chapter 1 - Cell Machinery
• Chapter 2 - Cellular Basis of Hematopoiesis
• Chapter 3 - Growth Factors
• Chapter 4 - Maturation of Blood Cells and Their Examination in Peripheral Blood and Bone Marrow
• Chapter 5 - Hypochromic Anemias
• Chapter 6 - The Porphyrias and Iron Overload
• Chapter 7 - Megaloblastic Anemias
• Chapter 8 - Hemolytic Anemias
• Chapter 9 - Genetic Disorders of Hemoglobin
• Chapter 10 - Benign Disorders of Phagocytes
• Chapter 11 - Benign Disorders of Lymphocytes
• Chapter 12 - Acute Leukemias
• Chapter 13 - Chronic Myeloid (Myelogenous) Leukemias and Myelodysplastc/Myeloproliferative Neoplasms
• Chapter 14 - Myelodysplastic Syndromes
• Chapter 15 - Myeloproliferative Disorders
• Chapter 16 - Histiocytic Disorders
• Chapter 17 - Aplastic and Dyserythropoietic Anemias
• Chapter 18 - Chronic Lymphoid Leukemias
• Chapter 19 - Non-Hodgkin Lymphomas: Mature B-Cell Neoplasms
• Chapter 20 - Peripheral T-Cell Disorders
• Chapter 21 - Hodgkin Lymphoma
• Chapter 22 - Myeloma and Related Conditions
• Chapter 23 - Tissue Typing and Stem Cell Transplantation
• Chapter 24 - Vascular and Platelet Bleeding Disorders
• Chapter 25 - The Inherited and Acquired Coagulation Disorders
• Chapter 26 - Thrombosis
• Chapter 27 - Secondary Anemia and Bone Marrow in Nonhematopoietic Disorders
• Chapter 28 - Parasitic Disorders
• Chapter 29 - Blood Transfusion 

Product Details 

• Hardcover: 544 pages
• Publisher: Mosby; 4 edition (August 25, 2009)
• Language: English
• ISBN-10: 0323044530
• ISBN-13: 978-0323044530
• Product Dimensions: 12.2 x 9.2 x 1.1 inches

List Price: $262.00