Gravlee: Cardiopulmonary Bypass: Principles and Practice 3rd Edition

Before embarking upon this third edition of Cardiopulmonary Bypass: Principles and Practice, the editors considered the shrinking clinical volumes of coronary artery bypass graft procedures, recent developments in percutaneous valve surgery, and the trend toward performing coronary artery bypass grafting (CABG) procedures without cardiopulmonary bypass (CPB). Did the need for a current and comprehensive reference source on CPB still exist? Obviously, we decided that CPB is alive and well, and that the timing is appropriate to craft the third edition of our textbook. Although certain surgical applications for CPB may have diminished, a variety of other developments and trends serve as growth areas for CPB and other circulatory support interventions. The increasing prevalence of congestive heart failure has stimulated interest in surgical procedures to reshape the heart and in longer-term applications of ventricular assist devices. As our population ages, the prevalence of aortic and mitral valve disease increases, and surgical repair or replacement remains the gold standard for these diseased valves. And at the opposite end of the age spectrum pediatric cardiac surgical teams are pushing the frontiers of correction of congenital heart malformations. In so doing they require ever more sophisticated applications of CPB. Minimally invasive cardiac surgical techniques offer promise for shorter hospitalization and faster return to normal activities. Many of these techniques require CPB, often with major technological refinements and miniaturization. Such changes have substantially reduced the physiologic trespass incurred by CPB since the first edition of this book was published in 1993. Yet the increasing age and risk profile of our patient population offsets these gains and creates a demand for continued fast-paced advancement of the disciplines engaged in CPB.
Ross Ungerleider and Al Stammers are new editors for the third edition. Both individuals bring substantial experience, expertise, and creativity to this edition. These editors represent the surgical and cardiovascular perfusion communities, respectively, thereby perpetuating the philosophy that this book should reflect the multidisciplinary nature of the clinical practice of CPB. Consequently, the editors and the chapter authors constitute a diverse mix of anesthesiologists, surgeons, cardiovascular perfusionists, and basic scientists.
This edition features a number of changes in content and organization. Rather than a single chapter, there is now an entire section with five chapters devoted to neonates, infants, and children. This makes sense, because the procedures, equipment, and complications for these patients often differ strikingly from those for adults. Two chapters have been added to specifically address patient safety and teamwork in CPB because both topics are so critical to improving patient outcomes. The hematology section has been reorganized and expanded, incorporating new chapters on coagulation testing and on pharmacologic prophylaxis for post-CPB bleeding. Since the second edition was published, the topic of minimally invasive extracorporeal circuitry has expanded beyond a single vendor and extracorporeal circuit, so Chapter 8 reflects these expanded options and applications.
As in the first and second editions, our mission is to provide a comprehensive source of clinical information about extracorporeal circulation as well as its underlying basic science principles. Practitioners and students of anesthesiology, surgery, and cardiovascular perfusion will most directly benefit from this book, but it should also appeal to neonatologists, cardiologists, and intensive care specialists.
Glenn P. Gravlee, Richard F. Davis, Alfred H. Stammers, Ross M. Ungerleider

New in this edition

• New section on pediatric applications.
• Discussions of outcomes data for on-pump and off-pump surgeries.
• New chapter on circulatory support for minimally invasive cardiac surgery.
• New material on low-volume circuits and other new equipment.

Contents
SECTION 1:HISTORY

• Historical Development of Cardiopulmonary Bypass in Minnesota
• The Birth of an Idea and the Development of Cardiopulmonary Bypass

SECTION II EQUIPMENT

• Blood Pumps in Cardiopulmonary Bypass
• Principles of Oxygenator Function: Gas Exchange, Heat transfer, and Operation
• Circuitry and Cannulation Techniques
• Ultrafiltration and Dialysis
• Mechanical Circulatory Support Devices
• Cardiopulmonary Bypass for Minimally Invasive Cardiac Surgery

SECTION III:PHYSIOLOGY AND PATHOLOGY

• Temperature Management in Cardiac Surgery
• Myocardial Protection
• Changes in the Pharmacokinetics and Pharmacodynamics of Drugs Administered During Cardiopulmonary Bypass
• Embolic Events
• Endocrine, Metabolic, and Electrolyte Responses
• Cardiopulmonary Bypass and the Lung
• Immune System and Inflammatory Responses to Cardiopulmonary Bypass
• Kidney Function and Cardiopulmonary Bypass
• Splanchnic Visceral, Metabolic, and Glucoregulatory Effects of Cardiopulmonary Bypass
• Neurologic Effects of Cardiopulmonary Bypass

SECTIION IV. HEMATOLOGY

• Hemodilution and Priming Solutions
• The Blood-Surface Interface
• Hematologic Effects and Coagulopathy
• Coagulation Testing
• Anticoagulation
• Heparin Neutralization
• Pharmacologic Prophylaxis Against Post-Cardiopulmonary Bypass Coagulopathy

SECTIN V: CLINICAL APPLICATIONS

• Conduct of Cardiopulmonary Bypass
• Teamwork: A Systems-Based Practice
• Primum Non Nocere: Patient Safety in Cardiopulmonary Bypass
• Unusual Problems in Cardiopulmonary Bypass
• Termination of Cardiopulmonary Bypass
• ECMO for Respiratory Support in Adults
• Perfusion for Thoracic Aortic Surgery
• Noncardiac Surgical Applications of Cardiopulmonary Bypass

SECTION VI. NEONATES, INFANTS, AND CHILDREN

• Pediatric Cardiopulmonary Bypass Overview:State of the Art and Future
• Myocardial Protection and Preservation for Neonates and Infants
• Brain Injury Following Infant Cardiac Surgery and Neuroprotective Strategies
• ECMO for Infants and Children
• Circulatory Assist Devices for Infants and Children

INDEX 

Product Details

• Hardcover: 816 pages
• Publisher: Lippincott Williams & Wilkins; Third edition (2008)
• Language: English
• ISBN-10: 0781768152
• ISBN-13: 978-0781768153
• Product Dimensions: 11.2 x 8.7 x 1.8 inches

List Price: $221.50