On publishing this Fourth Edition of Pediatric Critical Care, we are struck by how much the milieu of pediatric critical care medicine and the content of this textbook have changed over the last 2 decades. The first edition of Pediatric Critical Care appeared in 1992, only 5 years after the first Pediatric Critical Care Medicine certification examination. In fact, the first table of contents for Pediatric Critical Care was constructed to encompass the American Board of Pediatrics’ original content specifications for pediatric critical care medicine. Since then, most of the authors and editors of Pediatric Critical Care have survived recertification and are now actively engaged in “Maintenance of Certification.” However, the value of a comprehensive textbook such as Pediatric Critical Care remains constant; it continues to provide a comprehensive overview of pediatric critical care medicine for those working in the field.
That noted, the content of Pediatric Critical Care has certainly evolved through these four editions. Cardiopulmonary physiology still represents comfort food for most intensivists. Those concepts remain as fundamental as ever. However, the virtual explosion of molecular biology has fueled the expectation of personalized medicine. When the first edition of Pediatric Critical Care appeared, the Human Genome Project was just getting underway. Today, whole genome mapping is common in research, and, in the near future, it will probably become an element of the medical record.
Reanimation was once a comic book fantasy. Today, extracorporeal life support has become an integral component of cardiopulmonary resuscitation in many hospitals. Since the first systemic pulmonary shunt was performed in 1943, the advances in pediatric cardiac surgery and postoperative care have been nothing less than spectacular, including the growth of pediatric cardiac intensive care as a new focused subspecialty. A parallel pattern of subspecialization seems to be appearing in pediatric neurocritical care. Similarly, pediatric critical care medicine has clearly played a role in improved survival of hematology/oncology and hematopoietic progenitor cell transplantation patients.
At the time of the first edition of Pediatric Critical Care, family-centered care was merely an interesting and controversial concept. Now parents routinely contribute information during rounds to help inform the daily care plan. Pulmonary artery catheters were once in common use, often placed by cut-down vascular access. Today, a pediatric critical care medicine fellow is more likely to encounter a pulmonary artery catheter in a simulation laboratory, yet is skilled in vascular ultrasonography and echocardiography, techniques that facilitate placement of vascular catheters on the first pass and provide three-dimensional visualization of complex cardiac anatomy. Before the new millennium, pediatric and adult patients with hypoxemic respiratory failure were commonly supported by using tidal volumes of 10 to 15 mL/kg. Chest tube insertion equipment and draining systems were typically ordered to the bedside on initiation of mechanical ventilation because pneumothorax was an anticipated and frequent complication. Similarly, catheter-associated bloodstream infections were a troublesome and not unexpected complication of central venous catheterization. Meanwhile, over the past 20 years, there has been a remarkable decline in deaths from sudden infant death syndrome, and infants of ever-greater prematurity have survived.
Two publications, “To Err is Human: Building a Safer System” and “Crossing the Quality Chasm” would not appear until the twenty-first century and have ushered in a new hospital paradigm of continuous quality improvement. Although there have been huge advances in knowledge of the molecular pathophysiology of sepsis since the first edition of Pediatric Critical Care, basic critical care principles remain paramount: early detection; early, vigorous hemodynamic resuscitation; and early antibiotics—simple concepts that clearly save lives. Success in the field of pediatric critical care medicine has allowed a change in outcome focus of interventional clinical trials from death to long-term morbidity. Particularly over the last decade, pediatric critical care medicine has seen the emergence of clinical research networks that will continue to foster translation of important basic research into practice.
With the publication of the Fourth Edition of Pediatric Critical Care, the editors note that new challenges continue to emerge for practitioners, particularly in a field that is now overtly international in scope. Worldwide, roughly 25 children still die of sepsis every minute. Obesity now complicates the neurogenic-inflammatory-endocrine stress response to critical illness. A growing population of children with acquired immunodeficiency increasingly find their way into the pediatric intensive care unit, as do an increasing number of children with chronic complex conditions.
As in the past, although in debt to many, we remain particularity grateful to our families, friends, and colleagues who have been patiently supportive through three revisions of this textbook. We thank our new section editors as well as the hundreds of authors who have contributed to the success of this and former editions of the textbook. Lastly, we thank the members of the multidisciplinary teams who make pediatric critical care medicine work and the patients and families who allow us into their lives at a time when they are most vulnerable. Being a pediatric intensivist remains an amazing, challenging, rewarding, humbling, and privileged occupation.
We hope this Fourth Edition of Pediatric Critical Care will help nurture our evolving specialty.
Bradley P. Fuhrman and Jerry J. Zimmerman
Key Features
- Focus on the development, function, and treatment of a wide range of disease entities with the text's clear, logical, organ-system approach.
- Keep all members of the pediatric ICU team up to date with coverage of topics particularly relevant to their responsibilities.
Website Features
- Consult the book from any computer at home, in your office, or at any practice location.
- Instantly locate the answers to your clinical questions via a simple search query.
- Quickly find out more about any bibliographical citation by linking to its MEDLINE abstract.
- Self Assessment Questions: Review questions categorized by chapter.
Contents
Section I - Pediatric Critical Care: The Discipline
- Chapter 1 - History of Pediatric Critical Care
- Chapter 2 - The Intensivist in the New Hospital Environment: Patient Care and Stewardship of Hospital Resources
- Chapter 3 - The Nurse in Pediatric Critical Care
- Chapter 4 - Research in Pediatric Critical Care
- Chapter 5 - Proving the Point: Evidence-Based Medicine in Pediatric Critical Care
- Chapter 6 - Outcomes in Pediatric Critical Care Medicine: Implications for Health Services Research and Patient Care
- Chapter 7 - Safety and Quality Assessment in the Pediatric Intensive Care Unit
- Chapter 8 - Information Technology in Critical Care
- Chapter 9 - Family-Centered Care in the Pediatric Intensive Care Unit
- Chapter 10 - Ethics in Pediatric Intensive Care
- Chapter 11 - Ethical Issues in Death and Dying
- Chapter 12 - Palliative Care
- Chapter 13 - The Process of Organ Donation and Pediatric Donor Management
- Chapter 14 - Pediatric Transport: Shifting the Paradigm to Improve Patient Outcome
- Chapter 15 - Pediatric Vascular Access and Centeses
- Chapter 16 - Pediatric Intensive Care in Developing Countries
- Chapter 17 - Educating the Intensivist
Section II - Cardiovascular System
- Chapter 18 - Critical Care in Public Health Emergencies
- Chapter 19 - Structure and Function of the Heart
- Chapter 20 - Regional Circulation
- Chapter 21 - Principles of Invasive Monitoring
- Chapter 22 - Assessment of Cardiovascular Function
- Chapter 23 - Echocardiography and Noninvasive Diagnosis
- Chapter 24 - Diagnostic and Therapeutic Cardiac Catheterization
- Chapter 25 - Pharmacology of the Cardiovascular System
- Chapter 26 - Cardiopulmonary Interactions
- Chapter 27 - Myocardial Dysfunction, Ventricular Assist Devices, and Extracorporeal Life Support
- Chapter 28 - Disorders of Cardiac Rhythm
- Chapter 29 - Shock States
- Chapter 30 - Cardiac Bypass for Repair of Congenital Heart Disease in Infants and Children
- Chapter 31 - Critical Care After Surgery for Congenital Cardiac Disease
- Chapter 32 - Cardiac Transplantation
- Chapter 33 - Physiologic Foundations of Cardiopulmonary Resuscitation
- Chapter 34 - Performance of Cardiopulmonary Resuscitation in Infants and Children
Section III - Respiratory System
- Chapter 35 - Structure and Development of the Upper Respiratory System in Infants and Children
- Chapter 36 - Structure of the Respiratory System: Lower Respiratory Tract
- Chapter 37 - Physiology of the Respiratory System
- Chapter 38 - Control of Breathing and Acute Respiratory Failure
- Chapter 39 - Assessment and Monitoring of Respiratory Function
- Chapter 40 - Overview of Breathing Failure
- Chapter 41 - Ventilation/Perfusion Inequality
- Chapter 42 - Mechanical Dysfunction of the Respiratory System
- Chapter 43 - Noninvasive Monitoring in Children
- Chapter 44 - Specific Diseases of the Respiratory System: Upper Airway
- Chapter 45 - Asthma
- Chapter 46 - Neonatal Respiratory Disease
- Chapter 47 - Pneumonitis and Interstitial Disease
- Chapter 48 - Diseases of Pulmonary Circulation
- Chapter 49 - Mechanical Ventilation and Respiratory Care
- Chapter 50 - Noninvasive Ventilation: Concepts and Practice
- Chapter 51 - Ventilator-Induced Lung Injury
- Chapter 52 - Acute Respiratory Distress Syndrome in Children
- Chapter 53 - Extracorporeal Life Support
Section IV - Central Nervous System
- Chapter 54 - Pediatric Neurocritical Care
- Chapter 55 - Pediatric Neurologic Assessment and Monitoring
- Chapter 56 - Neuroimaging
- Chapter 57 - Structure, Function, and Development of the Nervous System
- Chapter 58 - Coma and Depressed Sensorium
- Chapter 59 - Intracranial Hypertension and Brain Monitoring
- Chapter 60 - Status Epilepticus
- Chapter 61 - Severe Traumatic Brain Injury in Infants and Children
- Chapter 62 - Hypoxic-Ischemic Encephalopathy: Pathobiology and Therapy of the Post-Resuscitation Syndrome in Children
- Chapter 63 - Stroke and Intracerebral Hemorrhage
- Chapter 64 - Acute Neuromuscular Diseases and Disorders
- Chapter 65 - Central Nervous System Infections Presenting to the Pediatric Intensive Care Unit
Section V - Renal, Endocrine, and Gastrointestinal Systems
- Chapter 66 - Renal Structure and Function
- Chapter 67 - Fluid and Electrolyte Issues in Pediatric Critical Illness
- Chapter 68 - Acid-Base Balance and Disorders
- Chapter 69 - Tests of Kidney Function in Children
- Chapter 70 - Renal Pharmacology
- Chapter 71 - Glomerulotubular Dysfunction and Acute Kidney Injury
- Chapter 72 - Pediatric Renal Replacement Therapy in the Intensive Care Unit
- Chapter 73 - Hypertension in the Pediatric Intensive Care Unit
- Chapter 74 - Cellular Respiration
- Chapter 75 - Nutrient Metabolism and Nutrition Therapy During Critical Illness
- Chapter 76 - Inborn Errors of Metabolism
- Chapter 77 - Common Endocrinopathies in the Pediatric Intensive Care Unit
- Chapter 78 - Diabetic Ketoacidosis
- Chapter 79 - Structure and Function of Hematopoietic Organs
- Chapter 80 - Thrombosis in Pediatric Intensive Care
- Chapter 81 - Hematology and Oncology Problems in the Intensive Care Unit
- Chapter 82 - Transfusion Medicine
- Chapter 83 - Critical Illness Involving Children Undergoing Hematopoietic Progenitor Cell Transplantation
- Chapter 84 - Hemoglobinopathies
- Chapter 85 - Gastrointestinal Structure and Function
- Chapter 86 - Disorders and Diseases of the Gastrointestinal Tract and Liver
- Chapter 87 - Gastrointestinal Pharmacology
- Chapter 88 - Acute Liver Failure, Liver Transplantation, and Extracorporeal Liver Support
- Chapter 89 - Acute Abdomen
Section VI - Immunity and Infection
- Chapter 90 - The Innate Immune System
- Chapter 91 - Infection and Host Response
- Chapter 92 - Congenital Immunodeficiencies
- Chapter 93 - Acquired Immune Dysfunction
- Chapter 94 - Bacterial Infection, Antimicrobial Use, and Antibiotic-Resistant Organisms in the Pediatric Intensive Care Unit
- Chapter 95 - Life-Threatening Viral Diseases and Their Treatment
- Chapter 96 - Infectious Syndromes in the Pediatric Intensive Care Unit
- Chapter 97 - Health Care–Associated Infection in the Pediatric Intensive Care Unit: Epidemiology and Control—Keeping Patients Safe
- Chapter 98 - Autoimmune Diseases: Diagnosis, Treatment, and Life-Threatening Complications
- Chapter 99 - Genomic and Proteomic Medicine in Critical Care
- Chapter 100 - Molecular Foundations of Cellular Injury: Necrosis, Apoptosis, and Autophagy
- Chapter 101 - Endotheliopathy
- Chapter 102 - Neuroendocrine–Immune Mediator Coordination and Disarray in Critical Illness
- Chapter 103 - Sepsis
- Chapter 104 - Inflammation and Immunity: Systemic Inflammatory Response Syndrome, Sepsis, Acute Lung Injury, and Multiple Organ Failure
Section VII - Environmental Hazards, Trauma, Pharmacology, and Anesthesia
- Chapter 105 - Principles of Toxin Assessment and Screening
- Chapter 106 - Toxidromes and Their Treatment
- Chapter 107 - Bites and Stings
- Chapter 108 - Heat Injury
- Chapter 109 - Accidental Hypothermia
- Chapter 110 - Drowning
- Chapter 111 - Burn and Inhalation Injuries
- Chapter 112 - Evaluation, Stabilization, and Initial Management After Multiple Trauma
- Chapter 113 - Child Abuse and Neglect
- Chapter 114 - Thoracic Injuries in Children
- Chapter 115 - Abdominal Trauma in Pediatric Critical Care
- Chapter 116 - Principles of Drug Disposition in the Critically Ill Child
- Chapter 117 - Molecular Mechanisms of Drug Actions: From Receptors to Effectors
- Chapter 118 - Adverse Drug Reactions and Drug-Drug Interactions
- Chapter 119 - Airway Management
- Chapter 120 - Organ System Considerations that Affect Anesthetic Management
- Chapter 121 - Anesthesia Principles and Operating Room Anesthesia Regimens
- Chapter 122 - Neuromuscular Blocking Agents
- Chapter 123 - Sedation and Analgesia
- Chapter 124 - Malignant Hyperthermia
Product Details
- Hardcover: 1776 pages
- Publisher: Mosby; 4 edition (April 14, 2011)
- Language: English
- ISBN-10: 0323073077
- ISBN-13: 978-0323073073
- Product Dimensions: 11.1 x 8.9 x 2.2 inches
List Price: $279.00