Focusing on the scientific basis of skin moisturization, this expanded Second Edition of Skin Moisturization explores a wide range of topics, from the biological aspects of the skin to the formulation of the active ingredients in skin moisturizers. Ideal for dermatologists, cosmetic scientists, and clinical scientists interested in the treatment of xerotic skin conditions, the text discusses the latest technology and trends in the ever-growing and expanding cosmetic industry.
Key features in the Second Edition:
- chapters that review the relevant research and recent clinical findings in the field of skin moisturization.
- an overview of clinical and consumer testing approaches and ex vivo evaluation procedures, including evaluation methodology, and regulatory and safety aspects of skin moisturizers.
- action efficacy and formulation of various moisturizing ingredients that include emollients, humectants, ceramides and other barrier lipids, alphahydroxyacids, and enzymes.
Part I Stratum Corneum and Epidermal Biology
- 1 The Keys to Epidermal Differentiation
- 2 Lipid Organization of the Skin Barrier
- 3 Untangling the Role of Keratin in Stratum Corneum
- 4 The Role of Filaggrin in Skin Diseases
- 5 Peptidylarginine Deiminases in Skin Biology
- 6 Cornified Envelope
- 7 Corneodesmosomal Proteins
- 8 Kallikrein-Related Peptidases: An Emerging Family of Pivotal Players in Epidermal Desquamation and Barrier Function
- 9 Aquaporins and Tight Junctions
- 10 Epidermal pH
Part II Xerotic Skin Conditions and SC Properties
- 11 The Molecular Aspects of Dry, Flaky Skin Conditions
- 12 Xerotic Skin Conditions and SC Properties: Diabetic Dry Skin
- 13 Skin Barrier Dysfunction in Atopic Dermatitis
- 14 Self-Perceived Sensitive Skin: A New Understanding Based on Epidermal Nerves
- 15 Psychological Stress and Skin
- 16 Stratum Corneum Biomechanics
Part III Efficacy of Moisturizers & Moisturizing Ingredients
- 17 Glycerol as Humectant in Cosmetic Formulations
- 18 Lanolin and the Skin
- 19 Moisturization Mechanisms: Internal Occlusion by Orthorhombic Lipid Phase Stabilizers - A Novel Mechanism of Action of Skin Moisturization
- 20 The Effects of Niacinamide-Containing Moisturizers
- 21 Urea As a Moisturizing and Barrier-Enhancing Ingredient
- 22 Hydroxyacids and Salicylic Acid
- 23 Stratum Corneum Serine Proteases and Effect of Inhibitors on Dry Skin
- 24 Cannabinoids and Pruritus
- 25 Microdermabrasion: Clinical, Histologic, and Molecular Effects
- 26 Cosmetic Benefits Derived from the Topical Application of Acid Proteases
- 27 Skin Moisturization by Dermonutrition
Part IV Novel Evaluation Methodologies
- 28 Capacitance Imaging for Viewing and Measuring Skin Surface Hydration
- 29 Vibrational Imaging and Microspectroscopy of Natural Moisturizing Factor Concentration in Human Corneocytes
- 30 Measuring Water Gradients Using Confocal Raman Microspectroscopy
- 31 New Developments in Skin Barrier Measurements
Index
Product Details
- Hardcover: 560 pages
- Publisher: Informa Healthcare; 2 edition (March 23, 2009)
- Language: English
- ISBN-10: 1420070940
- ISBN-13: 978-1420070941
- Product Dimensions: 9.1 x 6.2 x 1.2 inches
List Price: $300.00