Within the past 30 years photomedicine has developed from empiricism into one of the most exciting fields in biomedical research. Studies on the effects of visible and ultraviolet radiation on skin have led to a fruitful collaboration between basic scientists and clinicians. The successful use of the new ultraviolet techniques for the treatment of skin disease, along with a rapidly increasing understanding of the pathogenesis of photodermatoses, thereby markedly improving their treatment, have been the driving force for the development of a new subspecialty of photodermatology. This now encompasses the diagnosis and treatment of sunlight-induced disorders; all aspects of phototherapy, including the use of such new modalities as photodynamic therapy for skin tumors and other diseases; as well as photoprotection, which continues to evolve with the development of new generations of ultraviolet filters. In the past decade, therefore, very significant advances have occurred throughout this novel subspecialty, particularly in photoimmunology, molecular biology, and genetics. In more detail, these include better recognition and understanding of:
- Acute and chronic effects of ultraviolet radiation on the skin: in vitro studies, animal models, photoaging, and epidemiology of skin cancers;
- Clinical manifestation of photodermatoses: actinic prurigo, pin-head papule form of polymorphous light eruption, novel genetic mutations in porphyrias, and so on;
- Pathophysiology and treatment of photodermatoses: polymorphous light eruption, actinic prurigo, chronic actinic dermatitis, xeroderma pigmentatosum, photo-exacerbated dermatoses, and so on;
- The science of photoprotection: new ultraviolet filters, photoprotection by clothing, photoprotection by oral agents, and so on;
- Phototherapy: narrowband ultraviolet B, ultraviolet A1, visible light;
- Topical photodynamic therapy;
- Medical and cosmetic applications of laser and similar radiation sources; and
- New insight on the use of laser and radiation sources on people of color.
The book consists of six sections. Section I is on history and basic principles, followed by the effects of ultraviolet radiation on normal skin in Section II. Section III covers all the photodermatoses, while Section IV and V discuss photoprotection and ultraviolet and visible radiation therapy. Section VI is a practical description of testing methods used in photodermatology and guidelines of setting up a phototherapy and laser center.
Contents
Section I: History and Basic Principles
- 1. History of Human Photobiology
- 2. Basic Principles of Photobiology
- 3. Radiation Sources and Interaction with Skin
Section II: Effects of Ultraviolet Radiation on Normal Skin
- 4. The Molecular and Genetic Effects of Ultraviolet Radiation Exposure on Skin Cells
- 5. Photoimmunology
- 6. The Acute Effects of Ultraviolet Radiation on the Skin
- 7. The Chronic Effects of Ultraviolet Radiation on the Skin: Photoaging
- 8. The Chronic Effects of Ultraviolet Radiation on the Skin: Photocarcinogenesis
- 9. The Epidemiology of Skin Cancer
Section III: Photodermatoses
Part A: Basic Principles
- 10. Evaluation of the Photosensitive Patient
Part B: Immunologically-Mediated Photodermatoses
- 11. Polymorphous Light Eruption, Hydroa Vacciniforme, and Actinic Prurigo
- 12. Chronic Actinic Dermatitis
- 13. Solar Urticaria
Part C: Drug and Chemical-Induced Photosensitivity
- 14. Drug and Chemical Photosensitivity: Exogenous
- 15. Cutaneous Porphyrias
Part D: DNA Repair-Deficient Photodermatoses
- 16. Xeroderma Pigmentosum and Other DNA Repair-Deficient Photodermatoses
Part E: Photoaggravated Dermatoses
- 17. Photoaggravated Dermatoses
Section IV: Photoprotection
- 18. Photoprotection
- 19. Novel Developments in Photoprotection: Part I
- 20. Novel Developments in Photoprotection: Part II
- 21. Public Education in Photoprotection
Section V: Ultraviolet and Visible Radiation Therapy
- 22. Phototherapy with UVB: Broadband and Narrowband
- 23. Ultraviolet-A1 and Visible Light Therapy
- 24. Psoralen Photochemotherapy
- 25. Extracorporeal Photochemotherapy (Photopheresis)
- 26. Photodynamic Therapy
- 27. The Principles and Medical Applications of Lasers and Intense-Pulsed Light in Dermatology
- 28. Lasers and Energy Sources for Skin Rejuvenation and Epilation
- 29. Laser Treatment on Ethnic Skin
Section VI: Appendices
- Appendix A. Phototesting
- Appendix B. Photopatch Testing
- Appendix C. Guidelines for Setting Up a Phototherapy Referral Center or an Office-Based Phototherapy Unit
- Appendix D. Guidelines for Setting Up a Laser Center
Index
Book Details
- Hardcover: 496 pages
- Publisher: Informa Healthcare; 1 edition
- Language: English
- ISBN-10: 0849374960
- ISBN-13: 978-0849374968
- Product Dimensions: 10.1 x 7 x 1 inches
List Price: $250.00