The European Society for Medical Oncology (ESMO) is to be complimented for having decided to dedicate an issue of its “Handbook” series to geriatric oncology. The International Society for Geriatric Oncology (SIOG) has been happy to help in the task of developing this volume, which was initiated by Dirk Schrijvers, Branko Zakotnik, Riccardo Audisio, Hendrik van Halteren, Arti Hurria, and the undersigned. This handbook is not only for Europeans. Cancer is a disease related to ageing, and the proportion of senior patients increases worldwide. While the proportion of persons beyond age 70 is still small in developing countries, their numerous population means that there are more “elderlies” in India than in Europe.
The authors have done a major effort in providing in record time chapters that truly reflect the state of the art in the management of senior adults with cancer. Many questions in this advancing field need considerable work before adequate guidelines can be provided. Nevertheless, progress is being made and is reflected by the contributions.
Some diseases have not been discussed and interesting topics have not been addressed. This gap is filled by more comprehensive books, and today’s electronic communications allow one to explore any area of interest easily.
The treatment of any patient requires a careful evaluation of the person who is in need of such treatment. This is even truer for the seniors, who have less reserves to cope with cancer and its treatment. Therefore, this handbook leaves ample space for chapters that help in the delicate decisionmaking process, which should lead to the best therapy, adapted not only to the disease but also to the person who suffers from it. Annals of Oncology, the official journal of ESMO, and the soon-to-belaunched Journal of Geriatric Oncology, official journal of SIOG, will keep us updated, as will all major medical journals.
Chapter 1 Introduction
- Defining the Elderly
- Biology of Aging and Changes in Organ Function
- Changes in Cognition
- Cancer and Aging
- Clinical Aspects
- Introduction
- Population Demographics
- Cancer Demographics
- Society-Related Problems
- Introduction
- Short Screening Tools
- The Vulnerable Elders Survey
- MGA Packages
- Frailty in the Elderly
- The Impact of Frailty on Cancer
- Assessment of Frailty
- Conclusion
- Further Reading
- Introduction
- Indications for Surgery
- Patients Selection
- Outcomes
- Survival
- Palliation
- Side Effects
- Indications for Radiotherapy in the Elderly
- Side Effects of Radiotherapy in the Elderly (Acute and Late)
- Efficacy and Outcome of Radiotherapy in the Aging
- Palliative Setting: Toxicity and Efficacy Ratio
- Curative Setting: Combinations of Chemotherapy and Radiotherapy
- Selection Criteria for Radiotherapy in the Elderly
- Introduction
- Breast Cancer
- Prostate Cancer
- Introduction
- Chemotherapy in Senior Adults
- Targeted Therapies in Senior Adults
- Further Reading
- Introduction
- Diagnosis and Prognosis
- Treatment
- Diagnosis and Classification of Myeloproliferative Disorders
- Treatment Strategies of MPD in the Senior Patient
- The Relevance of Myelodysplastic Syndromes in the Elderly
- Classification and Risk Scoring in MDS
- Age-Adjusted Models and Assessment in Elderly MDS Patients
- Treatment Options in Elderly MDS Patients
- Future Perspectives
- Introduction
- Early Breast Cancer
- Metastatic Breast Cancer
- Introduction
- Early Non–Small Cell Lung Cancer in the Elderly
- Advanced Non–Small Cell Lung Cancer in the Elderly
- Small Cell Lung Cancer in the Elderly
- Palliative Treatment in Elderly Lung Cancer Patients
- Introduction
- Adjuvant Chemotherapy
- Metastatic Disease
- Introduction and General Background
- Treatment of Localized Prostate Cancer in Senior Adult Patients
- Treatment of Metastatic Prostate Cancer in Senior Adult Patients
- Incidence and Mortality
- Etiology and Risk Factors
- Pathology
- Natural History and Tumor Biology
- Signs and Symptoms
- Imaging, Cystoscopy, and Urinary Cytopathology
- Staging
- Treatment of NMIBC
- Surgical Treatment
- Radiotherapy
- Organ-Sparing Treatments
- Systemic Chemotherapy
- Prognosis of BC
- Follow-Up
- Introduction
- Cervical Cancer
- Uterine Cancer
- Special Types of Endometrial Malignancy
- Vaginal Cancer
- Vulvar Cancer
- Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
- Introduction
- Surgery
- Radiotherapy
- Chemotherapy
- Targeted Therapies
- Introduction
- Surgery in the Senior Cancer Patient
- Systemic Therapy of Metastatic Renal Cell Carcinoma in the Senior Cancer Patient
- Patient-Focused Approach
- Introduction
- Depression
- Anxiety
- Introduction
- Respect
- Admiration
- Attention
- Information
- Protection
- Diagnosis
- Care
- Time
- Caution
- Freedom
- Introduction
- The Assessment of Age
- Polypharmacy
- Management of the Caregiver
- Function of the Team
Product Details
- Authors: Dirk Schrijvers, Matti Aapro, Branko Zakotnik and Riccardo Audisio
- Paperback: 168 pages
- Publisher: Informa Healthcare; 1 edition (May 15, 2010)
- Language: English
- ISBN-10: 1841847097
- ISBN-13: 978-1841847092
- Product Dimensions: 7.2 x 4.8 x 0.5 inches