The ninth edition of Sleisenger and Fordtran's Gastrointestinal and Liver Disease is the first edition for which neither of the founding editors is serving as a principal editor—Dr. Fordtran stepped down as editor after publication of the fifth edition, and for this edition, Dr. Sleisenger is serving as consulting editor. In Dr. Sleisenger's place, one of us, Dr. Lawrence J. Brandt, has become a principal editor. Given the explosion of information in gastroenterology over the past 2 decades and the incorporation of liver disease into the textbook since the sixth edition, we believe that the book is best served by three editors, rather than two. That the book continues to serve as a state-of-the-art, user-friendly source for the spectrum of gastroenterologic and hepatic disorders is a tribute to the vision and efforts of its founding editors, John Fordtran and Marvin Sleisenger. The sixth edition was dedicated to Dr. Fordtran, and this edition is dedicated with equal admiration, appreciation, and affection to Dr. Sleisenger.
As with previous editions, the editors have relied on the gracious advice of reviewers, colleagues, and trainees and have incorporated many improvements and refinements into this edition. Every effort has been made to minimize redundancies, correct deficiencies, and improve the book's flow and organization. Completing an enhancement that was begun in the seventh edition, virtually all endoscopic and histologic figures are now in full color. The color figures are fully integrated with the text in each chapter, not segregated into a separate atlas section as in many other textbooks. To be certain that all figures are of the highest quality and clarity, we were assisted by an imaging editor, Dr. Kenneth R. McQuaid, whose contribution we gratefully acknowledge. Two gastrointestinal pathologists, Drs. Pamela Jensen and Edward L. Lee, helped individual authors and editors find selected classic histologic examples of various diseases. In addition, for the eighth edition, nearly all of the diagrams and algorithms have been redrawn in a uniform and visually appealing style that complements and enhances the text.The overall organization of the book remains similar to that of previous editions, although several chapters on new topics have been added and the placement of individual chapters has been refined. Moreover, fully one third of the contributing authors are new to this edition, thereby ensuring that the information is fresh, updated, and critically assessed; each contributor was chosen because of his or her expertise in the area covered and reputation for clarity and effectiveness as a writer. Since publication of the seventh edition in 2002, there has been a remarkable amount of new information in the field of gastroenterology; for example, at least 20 new drugs, including tegaserod for constipation-predominant irritable bowel syndrome, adefovir and entecavir for hepatitis B, and oxaliplatin, bevacizumab, and cetuximab for metastatic colon cancer, have been approved by the U.S. Food and Drug Administration. Every effort has been made to ensure that the content of the book is as current as possible.
Section I contains three chapters that deal with the Biology of the Gastrointestinal Tract and Liver and provides a cogent introduction to basic science relevant to gastroenterology. Basic pathophysiology also is incorporated into the chapters on specific diseases. Section II, as in the previous two editions, presents an Approach to Patients with Symptoms and Signs and includes chapters written by new authors, including Dr. DeVault (Symptoms of Esophageal Disease), the two Drs. Malagelada (Nausea and Vomiting), and Drs. Patel and Lembo (Constipation), as well as the stalwarts from previous editions. New authors for Section III on Nutrition in Gastroenterology—Drs. Mason, DeLegge, Becker, and Look—have joined veteran Dr. Klein to produce a veritable book-within-a-book that now includes separate chapters on Eating Disorders and on Obesity; the chapter on Food Allergies by Dr. Sampson also has been moved to this section. Section IV, Topics Involving Multiple Organs, has been expanded and reorganized. A new chapter has been added on Gastrointestinal Stromal Tumors (GISTs), by Dr. Demetri, and some chapters previously covered elsewhere in the book have been placed more appropriately in this section, including chapters on Eosinophilic Disorders of the Gastrointestinal Tract by Drs. Khan and Orenstein; Gastrointestinal Carcinoid Tumors and the Carcinoid Syndrome by Drs. Anthony and Kim; Vascular Lesions of the Gastrointestinal Tract by Dr. Brandt; Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm by Drs. Fischer and Matthews; and Radiation Injury to the Gastro-intestinal Tract by Drs. Cho and Antoine. Single chapters by Drs. Jain and Thiele and by Drs. Reinus and Riely now cover Gastrointestinal and Hepatic Manifestations of Systemic Diseases and Gastrointestinal and Hepatic Disorders in the Pregnant Patient, respectively, and an expanded chapter by Drs. Jensen and Norton covers Endocrine Tumors of the Pancreas and Gastrointestinal Tract. Dr. Kimmey concludes the section with a thoughtful review of Complications of Gastrointestinal Endoscopy.
The next several sections constitute what we like to refer to as the “organ recital” of gastrointestinal and liver diseases: Sections V through X cover the Esophagus, Stomach and Duodenum, Pancreas, Biliary Tract, Liver, and Small and Large Intestine, respectively. Each section begins with a consideration of anatomy, histology, embryology, and developmental abnormalities, as well as basic function of the organ (for example, motility and sensory function of the hollow organs and biochemical function of the solid organs). The highlights and new contributors are many. Among the changes since the seventh edition are incorporation of the discussion of nonsteroidal anti-inflammatory drug–induced gastric ulceration into the chapter on Peptic Ulcer Disease by Drs. Cryer and Spechler (in addition to the chapter on Helicobacter pylori by Drs. Graham and Sung); creation of an expanded chapter on Treatment of Peptic Ulcer Disease by Drs. Chan and Lau; revision of the chapter on Acute Pancreatitis by Dr. Steinberg; updating of the chapter on Gallstone Disease by Drs. Browning and Sreenarasimhaiah and of the chapter on Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Polyps of the Gallbladder by Dr. Persley (both chapters ably written in previous editions by our friend and colleague the late Dr. Lyman Bilhartz); and revision of the chapter on Sclerosing Cholangitis and Recurrent Pyogenic Cholangitis by Drs. Tung and Kowdley. New authors in the section on the Liver include the two Drs. Roy-Chowdhury (Liver Physiology and Energy Metabolism); Drs. Ahmed and Keeffe (Liver Chemistry and Function Tests); Dr. Stevens (Vascular Diseases of the Liver); Drs. Carithers and McClain (Alcoholic Liver Disease); Dr. Reid (Nonalcoholic Fatty Liver Disease); Drs. Shah and Kamath (Portal Hypertension and Gastrointestinal Bleeding); and Dr. Fontana (Acute Liver Failure). The single comprehensive chapter on Viral Hepatitis in the seventh edition has been divided into five separate chapters, which take advantage of the expertise of Drs. Sjogren, Perrillo, Nair, Berenguer, Wright, Krawczynski, Aggarwal, Heathcote, and Feld. In addition, a separate chapter on Liver Disease Caused by Anesthetics, Toxins, and Herbal Preparations, by Dr. Lewis, has been split off from the chapter on Liver Diseases Caused by Drugs by Drs. Teoh and G. Farrell.
New authors in the section on Small and Large Intestine include Drs. Kahn and Daum (Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine); Drs. Harrell and Chang (Intestinal Water and Electrolyte Transport); Drs. O'Mahony and Shanahan (Enteric Bacterial Flora and Bacterial Overgrowth); Dr. Buchman (Short Bowel Syndrome); Dr. Giannella (Infectious Enteritis and Proctocolitis and Bacterial Food Poisoning); Drs. Kelly and Lamont (Antibiotic-Associated Diarrhea, Pseudomembranous Enterocolitis, and Clostridium difficile-Associated Diarrhea and Colitis); Drs. Su and Lichtenstein (Ulcerative Colitis); Drs. Fox and Stollman (Diverticular Disease of the Colon); Dr. Talley (Irritable Bowel Syndrome); and Dr. Camilleri (Acute and Chronic Pseudo-obstruction).
Finally, the last section of the book, on Psychosocial Factors in Gastrointestinal Disease, includes a new author, Dr. Locke (A Biopsychosocial Understanding of Gastrointestinal Illness and Disease), and new chapters on Palliative Medicine in Patients with Advanced Gastrointestinal and Hepatic Disease by Drs. Marr and Weissman and on Complementary and Alternative Medicine Therapies in Gastrointestinal and Hepatic Disease by Drs. Hass and Brandt.
As in previous editions, a mini-outline with page citations is included at the start of each chapter, and each major section contains a listing of the chapters with page citations in that section. The high-quality glossy paper for which the book is known has been retained, as have extensive cross-referencing and a comprehensive index.
The eighth edition of this classic textbook is a living tribute to its founding editors, Drs. John Fordtran and Marvin Sleisenger. True to their vision, the eighth edition presents a critical overview of the state of gastrointestinal practice and its scientific basis by eminent authorities in their respective fields. International in scope, with authors from eleven countries, the book remains the definitive resource for all who provide care for patients with gastrointestinal and liver disorders.
Mark Feldman, Lawrence S. Friedman, Lawrence J. Brandt
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Contents
Volume 1
SECTION I - Biology of the Gastrointestinal Tract
- CHAPTER 1 - Gastrointestinal Hormones and Neurotransmitters
- CHAPTER 2 - Mucosal Immunity
- CHAPTER 3 - Cellular Growth and Neoplasia
SECTION II - Nutrition in Gastroenterology
- CHAPTER 4 - Nutritional Assessment and Management of the Malnourished Patient
- CHAPTER 5 - Nutrition in Gastrointestinal Diseases
- CHAPTER 6 - Obesity
- CHAPTER 7 - Bariatric Surgery
- CHAPTER 8 - Eating Disorders
- CHAPTER 9 - Food Allergies
SECTION III - Symptoms, Signs, and Biopsychosocial Issues
- CHAPTER 10 - Acute Abdominal Pain
- CHAPTER 11 - Chronic Abdominal Pain
- CHAPTER 12 - Symptoms of Esophageal Disease
- CHAPTER 13 - Dyspepsia
- CHAPTER 14 - Nausea and Vomiting
- CHAPTER 15 - Diarrhea
- CHAPTER 16 - Intestinal Gas
- CHAPTER 17 - Fecal Incontinence
- CHAPTER 18 - Constipation
- CHAPTER 19 - Gastrointestinal Bleeding
- CHAPTER 20 - Jaundice
- CHAPTER 21 - Biopsychosocial Issues in Gastroenterology
SECTION IV - Topics Involving Multiple Organs
- CHAPTER 22 - Oral Disease and Oral-Cutaneous Manifestations of Gastrointestinal and Liver Disease
- CHAPTER 23 - Diverticula of the Pharynx, Esophagus, Stomach, and Small Intestine
- CHAPTER 24 - Abdominal Hernias and Gastric Volvulus
- CHAPTER 25 - Foreign Bodies, Bezoars, and Caustic Ingestions
- CHAPTER 26 - Abdominal Abscesses and Gastrointestinal Fistulas
- CHAPTER 27 - Eosinophilic Disorders of the Gastrointestinal Tract
- CHAPTER 28 - Protein-Losing Gastroenteropathy
- CHAPTER 29 - Gastrointestinal Lymphomas
- CHAPTER 30 - Gastrointestinal Stromal Tumors (GISTs)
- CHAPTER 31 - Gastrointestinal Carcinoid Tumors (Gastrointestinal Neuroendocrine Tumors) and the Carcinoid Syndrome
- CHAPTER 32 - Endocrine Tumors of the Pancreas and Gastrointestinal Tract
- CHAPTER 33 - Gastrointestinal Consequences of Infection with Human Immunodeficiency Virus
- CHAPTER 34 - Gastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation
- CHAPTER 35 - Gastrointestinal and Hepatic Manifestations of Systemic Diseases
- CHAPTER 36 - Vascular Lesions of the Gastrointestinal Tract
- CHAPTER 37 - Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm
- CHAPTER 38 - Gastrointestinal and Hepatic Disorders in the Pregnant Patient
- CHAPTER 39 - Radiation Injury
- CHAPTER 40 - Complications of Gastrointestinal Endoscopy
SECTION V - Esophagus
- CHAPTER 41 - Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus
- CHAPTER 42 - Esophageal Neuromuscular Function and Motility Disorders
- CHAPTER 43 - Gastroesophageal Reflux Disease
- CHAPTER 44 - Barrett's Esophagus
- CHAPTER 45 - Esophageal Disorders Caused by Medications, Trauma, and Infection
- CHAPTER 46 - Tumors of the Esophagus
SECTION VI - Stomach and Duodenum
- CHAPTER 47 - Anatomy, Histology, Embryology, and Developmental Anomalies of the Stomach and Duodenum
- CHAPTER 48 - Gastric Neuromuscular Function and Neuromuscular Disorders
- CHAPTER 49 - Gastric Secretion
- CHAPTER 50 - Helicobacter pylori
- CHAPTER 51 - Gastritis and Gastropathies
- CHAPTER 52 - Peptic Ulcer Disease
- CHAPTER 53 - Treatment of Peptic Ulcer Disease
- CHAPTER 54 - Adenocarcinoma and Other Tumors of the Stomach
SECTION VII - Pancreas
- CHAPTER 55 - Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas
- CHAPTER 56 - Pancreatic Secretion
- CHAPTER 57 - Hereditary, Familial, and Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood
- CHAPTER 58 - Acute Pancreatitis
- CHAPTER 59 - Chronic Pancreatitis
- CHAPTER 60 - Tumors of the Pancreas
- CHAPTER 61 - Endoscopic Treatment of Pancreatic Disease
SECTION VIII - Biliary Tract
- CHAPTER 62 - Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract
- CHAPTER 63 - Biliary Tract Motor Function and Dysfunction
- CHAPTER 64 - Bile Secretion and the Enterohepatic Circulation
- CHAPTER 65 - Gallstone Disease
- CHAPTER 66 - Treatment of Gallstone Disease
- CHAPTER 67 - Acalculous Biliary Pain, Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Polyps of the Gallbladder
- CHAPTER 68 - Sclerosing Cholangitis and Recurrent Pyogenic Cholangitis
- CHAPTER 69 - Tumors of the Bile Ducts, Gallbladder, and Ampulla
- CHAPTER 70 - Endoscopic and Radiologic Treatment of Biliary Disease
Volume 2
SECTION IX - Liver
- CHAPTER 71 - Embryology, Anatomy, Histology, and Developmental Anomalies of the Liver
- CHAPTER 72 - Liver Physiology and Energy Metabolism
- CHAPTER 73 - Liver Chemistry and Function Tests
- CHAPTER 74 - Hemochromatosis
- CHAPTER 75 - Wilson Disease
- CHAPTER 76 - Other Inherited Metabolic Disorders of the Liver
- CHAPTER 77 - Hepatitis A
- CHAPTER 78 - Hepatitis B and D
- CHAPTER 79 - Hepatitis C
- CHAPTER 80 - Hepatitis E
- CHAPTER 81 - Hepatitis Caused by Other Viruses
- CHAPTER 82 - Bacterial, Parasitic, and Fungal Infections of the Liver, Including Liver Abscess
- CHAPTER 83 - Vascular Diseases of the Liver
- CHAPTER 84 - Alcoholic Liver Disease
- CHAPTER 85 - Nonalcoholic Fatty Liver Disease
- CHAPTER 86 - Liver Disease Caused by Drugs
- CHAPTER 87 - Liver Disease Caused by Anesthetics, Toxins, and Herbal Preparations
- CHAPTER 88 - Autoimmune Hepatitis
- CHAPTER 89 - Primary Biliary Cirrhosis
- CHAPTER 90 - Portal Hypertension and Gastrointestinal Bleeding
- CHAPTER 91 - Ascites and Spontaneous Bacterial Peritonitis
- CHAPTER 92 - Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Systemic Complications of Liver Disease
- CHAPTER 93 - Acute Liver Failure
- CHAPTER 94 - Tumors and Cysts of the Liver
- CHAPTER 95 - Liver Transplantation
SECTION X - Small and Large Intestine
- CHAPTER 96 - Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine
- CHAPTER 97 - Small Intestinal Motor and Sensory Function and Dysfunction
- CHAPTER 98 - Colonic Motor and Sensory Function and Dysfunction
- CHAPTER 99 - Intestinal Electrolyte Absorption and Secretion
- CHAPTER 100 - Digestion and Absorption of Nutrients and Vitamins
- CHAPTER 101 - Maldigestion and Malabsorption
- CHAPTER 102 - Enteric Microbiota and Small Intestinal Bacterial Overgrowth
- CHAPTER 103 - Short Bowel Syndrome
- CHAPTER 104 - Celiac Disease and Refractory Celiac Disease
- CHAPTER 105 - Tropical Diarrhea and Malabsorption
- CHAPTER 106 - Whipple's Disease
- CHAPTER 107 - Infectious Enteritis and Proctocolitis and Bacterial Food Poisoning
- CHAPTER 108 - Antibiotic-Associated Diarrhea, Pseudomembranous Enterocolitis, and Clostridium difficile-Associated Diarrhea and Colitis
- CHAPTER 109 - Intestinal Protozoa
- CHAPTER 110 - Intestinal Infections by Parasitic Worms
- CHAPTER 111 - Crohn's Disease
- CHAPTER 112 - Ulcerative Colitis
- CHAPTER 113 - Ileostomy, Colostomy, and Pouches
- CHAPTER 114 - Intestinal Ischemia
- CHAPTER 115 - Ulcers of the Small and Large Intestine
- CHAPTER 116 - Appendicitis
- CHAPTER 117 - Diverticular Disease of the Colon
- CHAPTER 118 - Irritable Bowel Syndrome
- CHAPTER 119 - Intestinal Obstruction
- CHAPTER 120 - Ileus and Pseudo-obstruction
- CHAPTER 121 - Tumors of the Small Intestine
- CHAPTER 122 - Colonic Polyps and Polyposis Syndromes
- CHAPTER 123 - Colorectal Cancer
- CHAPTER 124 - Other Diseases of the Colon and Rectum
- CHAPTER 125 - Diseases of the Anorectum
SECTION XI - Palliative, Complementary, and Alternative Medicine
- CHAPTER 126 - Palliative Care for Patients with Gastrointestinal and Hepatic Disease
- CHAPTER 127 - Complementary and Alternative Medicine
Product Details
- Hardcover: 2480 pages
- Publisher: Saunders; 9 edition (May 3, 2010)
- Language: English
- ISBN-10: 1416061894
- ISBN-13: 978-1416061892
- Product Dimensions: 11.9 x 9.5 x 5 inches
List Price: $359.00