Lecture Notes: Pharmacology of Glucocorticosteroids








PHARMACOLOGY OF GLUCOCORTICOSTEROIDS (GCS)

Equivalent GCS dose
(mg)
Mineralocorticoid potency
(relative)
Duration of action
(hours)
Plasma half-life (minutes)
Short-acting
Cortisone 25 1.0 8–12 60
Hydrocortisone 20 0.8 8–12 90
Intermediate-acting
Prednisone 5 0.25 24–36 60
Prednisolone 5 0.25 24–36 200
Methylprednisolone 4 0 24–36 180
Triamcinolone 4 0 24–36 300
Long-acting
Dexamethasone 0.75 0 36–54 200
Betamethasone 0.6 0 36–54 200


Reference:
Bolognia's Dermatology 2nd edition 
 

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