Dietary Modulation of Cell Signaling Pathways by Young-Joon Surh






The fine-tuning of cellular signaling pathways is pivotal for maintaining homeostasis in the living organism. Therefore, disruption of any of the signal transduction pathways can lead to severe cellular dysfunction. Current research continues to increase its attention on the role of nutrition and diet in modifying oxidative and inflammatory damage in the progression of disease. Dietary Modulation of Cell Signaling Pathways reviews some of the latest research findings, focusing on nutrient–gene interactions with particular emphasis on the intracellular signaling network. This volume will contribute to the developments in this rapidly expanding and highly important area of biomedical research.

Contents
Chapter 1 Intracellular Signaling Molecules as Targets of Selected Dietary Chemopreventive Agents
Chapter 2 Modulation of Cell Signal Transduction by Tea and Ginger
Chapter 3 Modulation of MAPK Pathways by Food Phytochemicals: Risks and Benefits
Chapter 4 Turmeric as Cure-Cumin: Promises, Problems, and Solutions
Chapter 5 Flavanols and NF-?B Activation: Relevance for Infl ammation and Associated Diseases
Chapter 6 Regulation of Infl ammation, Redox, and Glucocorticoid Signaling by Dietary Polyphenols
Chapter 7 Dietary Factors in Food: Induction of Nrf2-Mediated Defense Genes in Normal Cells versus Inhibition of Cell Growth Genes in Tumor Cells
Chapter 8 The Isothiocyanate Sulforaphane Induces the Phase 2 Response by Signaling of the Keap1–Nrf2–ARE Pathway: Implications for Dietary Protection against Cancer
Chapter 9 Nutritional Redox Homeostasis and Cellular Stress Response: Differential Role of Homocysteine and Acetylcarnitine
Chapter 10 Dietary Factors in the Regulation of Selenoprotein Biosynthesis
Chapter 11 Regulation of Signaling Pathways by Selenium in Cancer
Chapter 12 Modulation of Gene Expression by Dietary Carotenoids and Retinoids: Role in Cancer Prevention
Chapter 13 Targeting the Epigenome with Dietary Agents
Chapter 14 Effects of Astaxanthin on Microarray Profiling of Gene Expression Patterns of Glomerular Cells in Diabetic Mice
Chapter 15 Insulin Resistance and Inflammatory Signaling Pathways Modulated by High-Fat Diet
Chapter 16 Molecular Effect of Complex Food Matrices on Endothelial Functions—A Complex Issue to Study: The Case of Wine
Chapter 17 Role of Oxidative Stress in ß-Thalassemia and the Antioxidative Effect of Fermented Papaya Preparation
Chapter 18 Ginkgo Biloba Leaf Extract (EGb 761) Modulates Cell Signaling Associated with Amyloid Beta Oligomers in Alzheimer’s Disease
Index

Book Details 
  • Hardcover: 504 pages
  • Publisher: CRC Press; 1 edition (September 26, 2008)
  • Language: English
  • ISBN-10: 0849381487
  • ISBN-13: 978-0849381485
  • Product Dimensions: 9.1 x 6.1 x 1.2 inches
List Price: $162.95
 

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